APHON Chemo Certification Exam
1. How many people ages 0-21 are diagnosed with 15,000 - 16,000
cancer each year?
2. What are the top 2 pediatric oncology diagnoses 1. Leukemia - 29%
+ the % 2. Brain / CNS - 26%
3. What is the 5 yr survival rate for all peds onc All Dx: > 80%
diagnoses? ALL: 90%
For ALL? AML: 65%
For AML?
4. Natural cell death Apoptosis
5. Cell death from an insult that leads to rupture of Necrosis
the cell membrane and spilling of cell contents
6. Regulates normal cell growth and repair Proto-oncogenes
7. Blood cell production Hematopoiesis
8. Period of time when the pt's WBCs are the low- Nadir
est, from day 7-10
9. What time is when a pt is at the greatest risk for During Nadir
infection
10. Goal of chemo Stop cell cycle/growth from occur-
ring and coming back
11. Why are multiple chemo agents used? Resistance to a single chemo agent
can occur
12. Chemo cells OUT of bone marrow and in the Blasts
peripheral system
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1. How many people ages 0-21 are diagnosed with 15,000 - 16,000
cancer each year?
2. What are the top 2 pediatric oncology diagnoses 1. Leukemia - 29%
+ the % 2. Brain / CNS - 26%
3. What is the 5 yr survival rate for all peds onc All Dx: > 80%
diagnoses? ALL: 90%
For ALL? AML: 65%
For AML?
4. Natural cell death Apoptosis
5. Cell death from an insult that leads to rupture of Necrosis
the cell membrane and spilling of cell contents
6. Regulates normal cell growth and repair Proto-oncogenes
7. Blood cell production Hematopoiesis
8. Period of time when the pt's WBCs are the low- Nadir
est, from day 7-10
9. What time is when a pt is at the greatest risk for During Nadir
infection
10. Goal of chemo Stop cell cycle/growth from occur-
ring and coming back
11. Why are multiple chemo agents used? Resistance to a single chemo agent
can occur
12. Chemo cells OUT of bone marrow and in the Blasts
peripheral system
1/4
