Test Bank for Abrams’ Clinical Drug Therapy: Rationales for Nursing Practice, 12th Edition by Geralyn Frandsen | Complete Chapters 1–16 | Verified A+ Study Resource | 2025/2026

ABRAM’S CLINICAL DRUG THERAPY RATIONALES FOR
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NURSING PRACTICE 13th EDITION GERALYN FRANDSEN’S
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o TESTBANK/COMPLETE GUIDE 2024-2025/ALL CHAPTERS 1-61
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,Chapter 1: The Foundation of Pharmacology: Quality and Safety
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1. Apatientdiagnosed with obsessive–compulsive disorder has been prescribed oral
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paroxetine hydrochloride. What is the expected effect for this prescription?
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A. Curative effect on symptoms o o o




B. Systemic effect onsymptoms o o o




C. Localeffect on symptoms o o o




D. Parenteraleffect on symptoms o o o




ACCURATE ANSWER:-B o




REASONING:->>>Pharmaceutical drug that produce systemic effects are taken into the o o o o o o o o o




body, circulated through the bloodstream to their sites of action in various body tissues, and
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eventually eliminated from the body. Curative agents are given to cure a disease process. Inthis
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case, paroxetine hydrochloride will control the symptoms but not curethe disorder.
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Pharmaceutical drug with local effects, such as sunscreen and local anesthetics, act mainly at the o o o o o o o o o o o o o o




site of application. Paroxetine hydrochloride is not administered parenterally. Parenteral
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agentsare administered subcutaneously, intramuscularly, or intravenously.
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POINTS: 1 REFERENCE: p. 3, Introduction o o OBJ: 1
NAT: Hospital client Needs: Physiological Integrity: Pharmacological and Parenteral
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TherapiesTOP:
o Chapter: 1: The Foundation of Pharmacology: Quality and Safety
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KEY: Integrated Process: Nursing Process
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BLM: Cognitive Level: Understand oNOT: Multiple Choice o o o o




2. A hospital client has been prescribed an antibiotic. This pharmaceutical drug is a
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naturally occurringsubstance that has been cheG
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haOt Mis another name o o o o o oo o oo o




for this type of pharmaceutical drug?
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A. Synthetic drug o




B. Semisynthetic drug o




C. Biotechnology drug o




D. Prototypedrug o




ACCURATE ANSWER:-B o




REASONING:->>>Semisynthetic pharmaceutical drug (e.g., many antibiotics) are naturally o o o o o o o




occurring substances that have been chemically modified. Synthetic pharmaceutical drug are
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more standardized in their chemical characteristics, more consistent in their effects, and less
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likely to produce allergic reactions. Biotechnology pharmaceutical drug involve
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manipulating DNAand RNA and recombining genes into hybrid molecules that can be
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inserted into living organisms. Prototype pharmaceutical drug are the first drug of a particular
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group to be developed.
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POINTS: 1 REFERENCE: p. 3, Drug Sources o o o OBJ: 1
NAT: Hospital client Needs: Physiological Integrity: Pharmacological and Parenteral
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TherapiesTOP:
o Chapter: 1: The Foundation of Pharmacology: Quality and Safety
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KEY: Integrated Process: Nursing Process
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BLM: Cognitive Level: Understand oNOT: Multiple Choice o o o o




3. Whichclassification applies to morphine? o o o o




A. Centralnervous system depressant o o o




B. Centralnervous system stimulant o o o

, C. Anti-inflammatory
D. Antihypertensive
ACCURATE ANSWER:-A o




REASONING:->>>Pharmaceutical drug are classified according to their effects on particular o o o o o o o o o




body systems, their therapeutic uses, and their chemical characteristics. Morphine is classified
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as a central nervous system depressant and will produce this effect in the hospital client. A
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central nervous system stimulant increases attention and raises mood. An anti-inflammatory
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agent decreases inflammation at the site of tissue or joint inflammation. An antihypertensive
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agent reduces blood pressure.
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POINTS: 1 REFERENCE: p. 3,Drug o o




Classifications and PrototypesOBJ: 1
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NAT: Hospital client Needs: Physiological Integrity: Pharmacological and Parenteral
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TherapiesTOP:
o Chapter: 1: The Foundation of Pharmacology: Quality and Safety
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KEY: Integrated Process: Nursing Process
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BLM: Cognitive Level: Remember o NOT: Multiple Choice o o o o




4. A hospital client is administered amoxicillin. The generic name of this pharmaceutical drug
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belongs to whichdrug group?
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A. Selective serotonin reuptake inhibitors o o o




B. Diuretics
C. Penicillins
D. ACE inhibitors o




ACCURATE ANSWER:-C o




REASONING:->>>The generic name often indicates the drug group (e.g., pharmaceutical drug
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with generic names ending in “cillin” are penicillins). Selective serotonin reuptake
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inhibitors are pharmaceutical drugs
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that have antidepressant effects; SSRI is a broad classification, not a generic name. Diureticsare
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pharmaceutical drugs that increase urine output; diuretic is a broad classification, not a generic
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name. ACE inhibitor is the broad classification for the angiotensin receptor blockers, not the
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generic name.
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POINTS: 1 REFERENCE: p. 3, Drug Names o o o OBJ: 2
NAT: Hospital client Needs: Physiological Integrity: Pharmacological and Parenteral
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TherapiesTOP:
o Chapter: 1: The Foundation of Pharmacology: Quality and Safety
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KEY: Integrated Process: Nursing Process
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BLM: Cognitive Level: Understand o NOT: Multiple Choice o o o o




5. Theadministration ofdiphenhydramine is regulated by which U.S. government agency?
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A. PublicHealthService o o




B. Federal Trade Commission o o




C. Occupational Safetyand Health Administration o o o o




D. Food and Drug o o




Administration
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ACCURATE ANSWER:-D o

, REASONING:->>>The Food and Drug Administration approves pharmaceutical drug for o o o o o o o o




over- the-counter availability, including the transfer of pharmaceutical drug from prescription
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to OTC status, and mayrequire clinical trials to determine the safety and effectiveness of OTC
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use.The Public Health Service is regulated by the state to maintain the health of individual
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citizens of the state. The Federal Trade Commission regulates imports and exports throughout
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the nation. TheOccupational Safety and Health Administration regulates safetywithin the
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workplace.
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POINTS: 1 REFERENCE: p. 4,Prescriptionand Nonprescription o o o o




Pharmaceutical drug OBJ: 4 o o




NAT: Hospital client Needs: Physiological Integrity: Pharmacological and Parenteral
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TherapiesTOP:
o Chapter: 1: The Foundation of Pharmacology: Quality and Safety
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KEY: Integrated Process: Nursing Process
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BLM: Cognitive Level: Understand o NOT: Multiple Choice o o o o




6. In the U.S., the administration ofanabolic steroids is regulated bywhich law?
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A. TheFood, Drug, and Cosmetic Act of 1938 o o o o o o o




B. The Comprehensive Drug Abuse Prevention and Control Act
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C. TheHarrison Narcotic Act o o o




D. TheSherley Amendment o o




ACCURATE ANSWER:-B o




REASONING:->>>The Comprehensive Drug Abuse Prevention and Control Act regulates o o o o o o o o




the manufacture and distribution of narcotics, stimulants, depressants, hallucinogens, and
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anabolic steroids. The Food, Drug, and Cosmetic Act of 1938 revised and broadened FDA
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powers and responsibilities, giving the FDA control over drug safety. The Harrison Narcotic Act
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restricted the importation, manufacture, sale, and use ofopium,cocaine, marijuana, and other
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pharmaceuticaldrugthat the act defi GneRd AaDs E
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.T erley Amendment of1912
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prohibitedfraudulent claims of drug effectiveness.
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POINTS: 1 REFERENCE: p. 4,Prescriptionand Nonprescription o o o o




Pharmaceutical drug OBJ: 3 o o




NAT: Hospital client Needs: Physiological Integrity: Pharmacological and Parenteral
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TherapiesTOP:
o Chapter: 1: The Foundation of Pharmacology: Quality and Safety
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KEY: Integrated Process: Nursing Process
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BLM: Cognitive Level: Remember o NOT: Multiple Choice o o o o




7. A nursing attendant is responsible for maintaining an accurate count and record of the
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controlled substances on the nursing division. This nursing action is regulated bywhich
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U.S. law or agency? o o o




A. TheFood, Drug, and Cosmetic Act of 1938 o o o o o o o




B. ThePublic Health Service o o o




C. TheDrug Enforcement Administration o o o




D. TheSherleyAmendment o o




ACCURATE ANSWER:-C
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