NURSE PRACTITIONER EXAM PRACTICE-QUESTION AND COLLECT
ANSWERS (VERIFIED ANSWERS) PLUS RATIONALES 2025/2026 Q&A
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1. Which of the following findings is most consistent with community-acquired pneumonia?
A. Fever, productive cough, and rales
B. Non-productive cough with clear lungs
C. No fever and normal chest X-ray
D. Hematuria and flank pain
Answer: A. Fever, productive cough, and rales
Rationale: Classic pneumonia presents with fever, cough, purulent sputum, and
abnormal lung sounds.
2. Which antihypertensive is contraindicated in pregnancy?
A. Methyldopa
B. Labetalol
C. ACE inhibitors
D. Hydralazine
Answer: C. ACE inhibitors
Rationale: ACE inhibitors are teratogenic and contraindicated in pregnancy; methyldopa
and labetalol are safer.
3. A patient with type 2 diabetes presents with foot ulcer. What is the priority exam?
A. Measure ankle-brachial index
B. Check capillary refill only
C. Perform chest X-ray
D. Complete blood count
Answer: A. Measure ankle-brachial index
Rationale: Assessing vascular supply is critical for wound healing and risk of ischemia.
4. First-line treatment for generalized anxiety disorder is:
A. Benzodiazepines
B. SSRIs
C. Beta-blockers
D. MAOIs
Answer: B. SSRIs
, Rationale: SSRIs are the first-line pharmacologic therapy for GAD; benzodiazepines are
for short-term use.
5. Which vaccine is recommended for adults ≥65 years old?
A. Varicella
B. HPV
C. Pneumococcal
D. Rotavirus
Answer: C. Pneumococcal
Rationale: Pneumococcal vaccination reduces risk of pneumonia and sepsis in older
adults.
6. Which condition is a contraindication to beta-blocker therapy?
A. Hypertension
B. Angina
C. Asthma
D. Migraine prophylaxis
Answer: C. Asthma
Rationale: Beta-blockers can cause bronchospasm in asthma patients.
7. A 72-year-old male presents with BPH. Which medication is most appropriate?
A. Finasteride
B. Tamoxifen
C. Levothyroxine
D. Insulin
Answer: A. Finasteride
Rationale: Finasteride (5-alpha reductase inhibitor) reduces prostate size and symptoms.
8. Which of the following is most characteristic of iron deficiency anemia?
A. Macrocytic anemia
B. Normocytic anemia
C. Microcytic hypochromic anemia
D. Pancytopenia
Answer: C. Microcytic hypochromic anemia
, Rationale: Low iron causes small, pale red blood cells.
9. Which medication is first-line for acute asthma exacerbation?
A. Salmeterol
B. Albuterol
C. Prednisone (oral)
D. Montelukast
Answer: B. Albuterol
Rationale: Short-acting beta-agonists (SABA) provide rapid bronchodilation.
10. A 60-year-old smoker presents with painless hematuria. Most concerning diagnosis?
A. UTI
B. Kidney stones
C. Bladder cancer
D. BPH
Answer: C. Bladder cancer
Rationale: Painless hematuria in smokers is highly suspicious for bladder cancer.
11. Which lab is most useful for monitoring long-term diabetes control?
A. Random glucose
B. Hemoglobin A1C
C. Fasting insulin
D. C-peptide
Answer: B. Hemoglobin A1C
Rationale: HbA1C reflects average glucose over 2–3 months.
12. Which heart sound is associated with heart failure?
A. S1
B. S2 split
C. S3
D. Murmur
Answer: C. S3
Rationale: S3 gallop indicates fluid overload and poor ventricular compliance.
ANSWERS (VERIFIED ANSWERS) PLUS RATIONALES 2025/2026 Q&A
|INSTANT DOWNLOAD PDF
1. Which of the following findings is most consistent with community-acquired pneumonia?
A. Fever, productive cough, and rales
B. Non-productive cough with clear lungs
C. No fever and normal chest X-ray
D. Hematuria and flank pain
Answer: A. Fever, productive cough, and rales
Rationale: Classic pneumonia presents with fever, cough, purulent sputum, and
abnormal lung sounds.
2. Which antihypertensive is contraindicated in pregnancy?
A. Methyldopa
B. Labetalol
C. ACE inhibitors
D. Hydralazine
Answer: C. ACE inhibitors
Rationale: ACE inhibitors are teratogenic and contraindicated in pregnancy; methyldopa
and labetalol are safer.
3. A patient with type 2 diabetes presents with foot ulcer. What is the priority exam?
A. Measure ankle-brachial index
B. Check capillary refill only
C. Perform chest X-ray
D. Complete blood count
Answer: A. Measure ankle-brachial index
Rationale: Assessing vascular supply is critical for wound healing and risk of ischemia.
4. First-line treatment for generalized anxiety disorder is:
A. Benzodiazepines
B. SSRIs
C. Beta-blockers
D. MAOIs
Answer: B. SSRIs
, Rationale: SSRIs are the first-line pharmacologic therapy for GAD; benzodiazepines are
for short-term use.
5. Which vaccine is recommended for adults ≥65 years old?
A. Varicella
B. HPV
C. Pneumococcal
D. Rotavirus
Answer: C. Pneumococcal
Rationale: Pneumococcal vaccination reduces risk of pneumonia and sepsis in older
adults.
6. Which condition is a contraindication to beta-blocker therapy?
A. Hypertension
B. Angina
C. Asthma
D. Migraine prophylaxis
Answer: C. Asthma
Rationale: Beta-blockers can cause bronchospasm in asthma patients.
7. A 72-year-old male presents with BPH. Which medication is most appropriate?
A. Finasteride
B. Tamoxifen
C. Levothyroxine
D. Insulin
Answer: A. Finasteride
Rationale: Finasteride (5-alpha reductase inhibitor) reduces prostate size and symptoms.
8. Which of the following is most characteristic of iron deficiency anemia?
A. Macrocytic anemia
B. Normocytic anemia
C. Microcytic hypochromic anemia
D. Pancytopenia
Answer: C. Microcytic hypochromic anemia
, Rationale: Low iron causes small, pale red blood cells.
9. Which medication is first-line for acute asthma exacerbation?
A. Salmeterol
B. Albuterol
C. Prednisone (oral)
D. Montelukast
Answer: B. Albuterol
Rationale: Short-acting beta-agonists (SABA) provide rapid bronchodilation.
10. A 60-year-old smoker presents with painless hematuria. Most concerning diagnosis?
A. UTI
B. Kidney stones
C. Bladder cancer
D. BPH
Answer: C. Bladder cancer
Rationale: Painless hematuria in smokers is highly suspicious for bladder cancer.
11. Which lab is most useful for monitoring long-term diabetes control?
A. Random glucose
B. Hemoglobin A1C
C. Fasting insulin
D. C-peptide
Answer: B. Hemoglobin A1C
Rationale: HbA1C reflects average glucose over 2–3 months.
12. Which heart sound is associated with heart failure?
A. S1
B. S2 split
C. S3
D. Murmur
Answer: C. S3
Rationale: S3 gallop indicates fluid overload and poor ventricular compliance.
