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Nuclear Medicine – NMTCB Practice Exam 2025/2026 | 150 Questions with Answers | Radiopharmaceuticals, Dose Calibrator, Quality Control – Radiology

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This fully solved practice exam includes 150 expertly structured multiple-choice questions with precise answers, designed specifically for candidates preparing for the NMTCB (Nuclear Medicine Technology Certification Board) Exam 2025/2026. The document comprehensively covers topics essential for certification in nuclear medicine, providing both theoretical understanding and clinical context. Key focus areas include radiopharmaceutical preparation and labeling (e.g., Tc99m kits, sulfur colloid, MAA, MAG3), radionuclidic and radiochemical purity, dose calibrator operation and QC (constancy, linearity, geometry), radiation physics, image artifacts, decay calculations, SPECT/PET imaging techniques, renal and hepatobiliary studies, GI bleed detection, lung scans, thyroid imaging, radiation protection protocols (NRC, DOT), and advanced clinical applications such as cardiac studies and oncology imaging. The document is rich in scenario-based questions and calculations, helping students strengthen both recall and applied problem-solving skills. It's presented in a clean, accessible Q&A format ideal for study sessions, mock exams, or quick revision. This resource is particularly useful for students enrolled in: – Nuclear Medicine Technology programs – Radiologic Technology with NM specialization – Medical Imaging and Radiopharmacy programs – CT, PET/CT, or hybrid modality certification prep It is applicable across U.S. universities, accredited radiologic science programs, and medical imaging institutions preparing future technologists for board-level competency. Keywords: NMTCB exam prep, nuclear medicine questions, radiopharmaceuticals, Tc99m kits, dose calibrator QC, SPECT imaging, PET/CT protocols, NRC regulations, MAA particle calculation, renal scan radiotracers, gamma camera QC, radiologic physics, thyroid imaging, radiation safety, radionuclidic purity, radiology board review

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NMTCB Practice Exam 2025/2026 Exam
Questions and Answers | 100% Solved



In which RP is Tc99m left in the valence state of +7

a. sulfur colloid

b. MAA

c. MAG3


d. sestamibi - 🧠 ANSWER ✔✔A. Sulfur colloid


a tech receives a request for a patient to receive Sm153 for palliation of

pain from bone mets. the patient has a WBC count of 3500 and 40000

platelets. what should happen next?

a. the order should be changed to Sr89

b. the tx should be delayed until the platelet ct is at least 60,000

,c. the tx should be delayed until the WBC is below 2400


d. the Sm153 should be ordered - 🧠 ANSWER ✔✔B. the tx should be

delayed until the platelet ct is at least 60,000

a SC kit requires the addition of 1-3 ml containing no more than 500mCi of

TcO4-. in addition, 1.5 ml of solution A must be added before boiling, and

1.5 ml of Solution B must be added after cooling. If the kit is correctly

prepared, what is the max concentration of Tc99m it could contain?

a. 83 mCi/ml

b. 125 mCi/ml

c. 167 mCi/ml


d. 500 mCi/ml - 🧠 ANSWER ✔✔B. 125 mCi/ml




max. 1 ml TcO4- containing 500 mCi

500/(1.5+1.5+1) = 125 mCi/ml

A hine-duley phantom is useful for testing the spatial resolution and spatial

linearity with only one image.

a. true

,b. false - 🧠 ANSWER ✔✔B. false


the advantage of a lung ventilation scan performed with Xenon is

a. the ability to match perfusion and vent positioning

b. the ability to detect delayed washout

c. the ability to perform the exam at the patient's bedside

d. the ability to perform perfusion before ventilation without increasing the

dose given for the vent study - 🧠 ANSWER ✔✔B. the ability to detect

delayed washout

A diphosphonate kit contian 180 mCi of Tc99m in 30 ml when it is prepared

at 8am. Immediately, a 20 mCi dose is withdrawn for a bone scan. if the

patient arrives late at 9:30 and half the volume is accidentally discharged,

how much volume from the kit must now be added to the syringe to correct

the dose to 20 mCi? (no other doses have been withdrawn meanwhile, and

the decay factor for 1.5 hrs is 0.841)

a. 1.5 ml

b. 2.0 ml

c. 2.3 ml



COPYRIGHT©PROFFKERRYMARTIN 2025/2026. YEAR PUBLISHED 2025. COMPANY REGISTRATION NUMBER: 619652435. TERMS OF USE.
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, d. 2.5 ml


e. 2.7 ml - 🧠 ANSWER ✔✔C. 2.3 mL




lots of math, sorry :(

a WBS bone scan film shows a good posterior image, but the anterior view

appears diffuse with greater soft tissue activity. what is the probable

cause?

a. wrong collimator used for anterior

b. increased patient to detector distance on the ant relative to the post

c. low tagging efficiency of the RP

d. patient was not sufficiently hydrated


e. none of the above - 🧠 ANSWER ✔✔b. increased patient to detector

distance on the ant relative to the post

Which of the following will not reduce the probability of contamination from

perspiration and saliva of a therapy patient?

a. disposable eating utensils

b. plastic covering over the mattress

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