AGACNP ANCC Boards- Heme-onc
32 yo presents with c/o fever, night sweats and unexplained wt loss. Upon exam you be aware a
swollen cervical lymph node. A subsequent CXR famous mediastinal adenopathy. Which of the
subsequent is the dx? - ANS-Hodgkins Lymphoma
Alcoholics and anemia - ANS-folic acid deficiency
ALL - ANS--pancytopenia with circulating blasts
-more commonplace in youngsters
-bone pain, fever, infections
-bone marrow with >20% blasts plus markers TDT and cALLa
-CNS prophylaxis with ARA-C
AML - ANS--eighty% of acute leukemia in adults
-hx of publicity to benzene, radiation, chemo
-remission charges from 50 to eighty five%
anemia of continual ailment - ANS-normochromic (32-36%), normocytic (mcv 80-a hundred)
the most common in-sanatorium anemia AND most common in the aged population
-tx is NOT to give iron however to deal with the underlying cause
anemia of chronic dz labs - ANS-MCV is everyday
MCHC is ordinary
serum iron is LOW
TIBC is LOW
Ferritin is HIGH (>100)
any lymph node >1cm lasting four-6 weeks now not related w infection, subsequent step -
ANS-biopsy
CLL - ANS-**maximum commonplace leukemia in adults
WBC > 60
absolute lymphocyte remember >50
median surivival is 10 years
CML - ANS-Philadelphia chromosome (t922 and BCR-ADL also seen)
differential w PMNs
takes place most customarily in people elderly forty or older
cryoprecipitate - ANS-to maintain fibrinogen degree
, DIC Labs - ANS-thrombocytopenia (PLTS <50k)
fibrinogen <170 mg/dL
decrease RBCs
incresse FDPs
prolonged PT (>19 seconds)
prolonged PTT (>forty two seconds)
+ Ddimer
FFP - ANS-update clotting elements
Folic Acid Deficiency - ANS-macrocytic normochromic
-tea and toast food plan, alcoholic
sx: fatigue, DOE, pallor, headache, GLOSSITIS*
**no neuro sx (differentiates it from B12 def)
generalized lympadenopathy + weight loss - ANS-assume leukemia
Hodgkins Lymphoma - ANS-Reed-Sternberg cells
typically affords with cervical adenopathy and spreads in a predictable fashion alongside lymph
node companies
most common in men average age is 32
How to distinguish SLE from ITP? - ANS-bone marrow aspiration
Iron Def Anemia s/s - ANS-PICA- uncommon meals yearning including ice, clay and many
others
dyspnea and slight fatigue w exercising
headache
weakness
palpitations
Iron Deficiency Anemia - ANS-microcytic, hypochromic
Iron Deficiency Anemia Diagnostics - ANS-Low serum iron
low serum ferritin (iron stores)
excessive TIBC (binding capacity) (>450)
high RDW (pink cellular distribution width) **
low MCV
low MCHC (hypochromic)
low Hgb
low RBC
low Hct
32 yo presents with c/o fever, night sweats and unexplained wt loss. Upon exam you be aware a
swollen cervical lymph node. A subsequent CXR famous mediastinal adenopathy. Which of the
subsequent is the dx? - ANS-Hodgkins Lymphoma
Alcoholics and anemia - ANS-folic acid deficiency
ALL - ANS--pancytopenia with circulating blasts
-more commonplace in youngsters
-bone pain, fever, infections
-bone marrow with >20% blasts plus markers TDT and cALLa
-CNS prophylaxis with ARA-C
AML - ANS--eighty% of acute leukemia in adults
-hx of publicity to benzene, radiation, chemo
-remission charges from 50 to eighty five%
anemia of continual ailment - ANS-normochromic (32-36%), normocytic (mcv 80-a hundred)
the most common in-sanatorium anemia AND most common in the aged population
-tx is NOT to give iron however to deal with the underlying cause
anemia of chronic dz labs - ANS-MCV is everyday
MCHC is ordinary
serum iron is LOW
TIBC is LOW
Ferritin is HIGH (>100)
any lymph node >1cm lasting four-6 weeks now not related w infection, subsequent step -
ANS-biopsy
CLL - ANS-**maximum commonplace leukemia in adults
WBC > 60
absolute lymphocyte remember >50
median surivival is 10 years
CML - ANS-Philadelphia chromosome (t922 and BCR-ADL also seen)
differential w PMNs
takes place most customarily in people elderly forty or older
cryoprecipitate - ANS-to maintain fibrinogen degree
, DIC Labs - ANS-thrombocytopenia (PLTS <50k)
fibrinogen <170 mg/dL
decrease RBCs
incresse FDPs
prolonged PT (>19 seconds)
prolonged PTT (>forty two seconds)
+ Ddimer
FFP - ANS-update clotting elements
Folic Acid Deficiency - ANS-macrocytic normochromic
-tea and toast food plan, alcoholic
sx: fatigue, DOE, pallor, headache, GLOSSITIS*
**no neuro sx (differentiates it from B12 def)
generalized lympadenopathy + weight loss - ANS-assume leukemia
Hodgkins Lymphoma - ANS-Reed-Sternberg cells
typically affords with cervical adenopathy and spreads in a predictable fashion alongside lymph
node companies
most common in men average age is 32
How to distinguish SLE from ITP? - ANS-bone marrow aspiration
Iron Def Anemia s/s - ANS-PICA- uncommon meals yearning including ice, clay and many
others
dyspnea and slight fatigue w exercising
headache
weakness
palpitations
Iron Deficiency Anemia - ANS-microcytic, hypochromic
Iron Deficiency Anemia Diagnostics - ANS-Low serum iron
low serum ferritin (iron stores)
excessive TIBC (binding capacity) (>450)
high RDW (pink cellular distribution width) **
low MCV
low MCHC (hypochromic)
low Hgb
low RBC
low Hct
