NSG 5340 Advanced Pharmacology
Midterm Practice Exam Questions And
Correct Answers (Verified Answers) Plus
Rationales 2025|2026 Q&A | Instant
Download Pdf| South College
1. Which of the following best describes the mechanism of action of
beta-blockers?
a) Increase cardiac contractility
b) Block beta-adrenergic receptors
c) Increase heart rate
d) Stimulate renin release
Beta-blockers reduce sympathetic stimulation by blocking beta-
adrenergic receptors, lowering heart rate and blood pressure.
2. Which class of antibiotics inhibits bacterial cell wall synthesis?
a) Macrolides
, b) Beta-lactams
c) Tetracyclines
d) Aminoglycosides
Beta-lactam antibiotics (penicillins, cephalosporins) inhibit bacterial
cell wall synthesis, leading to cell lysis.
3. What is the primary adverse effect of ACE inhibitors?
a) Bradycardia
b) Hyperglycemia
c) Dry cough
d) Hypokalemia
ACE inhibitors increase bradykinin levels, often causing a persistent
dry cough.
4. Which drug is considered first-line therapy for Type 2 Diabetes
Mellitus?
a) Insulin
b) Sulfonylureas
c) Metformin
d) Thiazolidinediones
Metformin is the first-line agent due to its efficacy, weight neutrality,
and cardiovascular benefit.
5. Which anticoagulant requires monitoring with INR?
a) Dabigatran
b) Warfarin
, c) Rivaroxaban
d) Apixaban
Warfarin requires INR monitoring due to its narrow therapeutic index
and dietary/drug interactions.
6. Which medication is most appropriate for acute asthma exacerbation?
a) Inhaled corticosteroid
b) Short-acting beta agonist (SABA)
c) Leukotriene receptor antagonist
d) Long-acting beta agonist (LABA)
SABAs (e.g., albuterol) provide rapid bronchodilation during acute
exacerbations.
7. Which of the following is a common side effect of SSRIs?
a) Constipation
b) Weight loss
c) Sexual dysfunction
d) Hypotension
SSRIs frequently cause sexual dysfunction, which can affect
adherence.
8. Which antibiotic is contraindicated in pregnancy due to risk of tooth
discoloration in the fetus?
a) Penicillin
b) Tetracycline
c) Cephalosporin
, d) Erythromycin
Tetracyclines deposit in developing teeth and bones, causing
discoloration and growth inhibition.
9. Which drug is most effective for the management of acute angina?
a) Beta-blocker
b) Calcium channel blocker
c) Sublingual nitroglycerin
d) ACE inhibitor
Sublingual nitroglycerin rapidly relieves angina by vasodilation,
reducing myocardial oxygen demand.
10. What is the black box warning for fluoroquinolones?
a) Hepatotoxicity
b) Tendon rupture
c) Ototoxicity
d) Nephrotoxicity
Fluoroquinolones can cause tendon rupture, especially in older adults
and those on corticosteroids.
11. Which antihypertensive is preferred in African American patients
without CKD?
a) ACE inhibitors
b) Beta-blockers
c) Thiazide diuretics
d) ARBs
Midterm Practice Exam Questions And
Correct Answers (Verified Answers) Plus
Rationales 2025|2026 Q&A | Instant
Download Pdf| South College
1. Which of the following best describes the mechanism of action of
beta-blockers?
a) Increase cardiac contractility
b) Block beta-adrenergic receptors
c) Increase heart rate
d) Stimulate renin release
Beta-blockers reduce sympathetic stimulation by blocking beta-
adrenergic receptors, lowering heart rate and blood pressure.
2. Which class of antibiotics inhibits bacterial cell wall synthesis?
a) Macrolides
, b) Beta-lactams
c) Tetracyclines
d) Aminoglycosides
Beta-lactam antibiotics (penicillins, cephalosporins) inhibit bacterial
cell wall synthesis, leading to cell lysis.
3. What is the primary adverse effect of ACE inhibitors?
a) Bradycardia
b) Hyperglycemia
c) Dry cough
d) Hypokalemia
ACE inhibitors increase bradykinin levels, often causing a persistent
dry cough.
4. Which drug is considered first-line therapy for Type 2 Diabetes
Mellitus?
a) Insulin
b) Sulfonylureas
c) Metformin
d) Thiazolidinediones
Metformin is the first-line agent due to its efficacy, weight neutrality,
and cardiovascular benefit.
5. Which anticoagulant requires monitoring with INR?
a) Dabigatran
b) Warfarin
, c) Rivaroxaban
d) Apixaban
Warfarin requires INR monitoring due to its narrow therapeutic index
and dietary/drug interactions.
6. Which medication is most appropriate for acute asthma exacerbation?
a) Inhaled corticosteroid
b) Short-acting beta agonist (SABA)
c) Leukotriene receptor antagonist
d) Long-acting beta agonist (LABA)
SABAs (e.g., albuterol) provide rapid bronchodilation during acute
exacerbations.
7. Which of the following is a common side effect of SSRIs?
a) Constipation
b) Weight loss
c) Sexual dysfunction
d) Hypotension
SSRIs frequently cause sexual dysfunction, which can affect
adherence.
8. Which antibiotic is contraindicated in pregnancy due to risk of tooth
discoloration in the fetus?
a) Penicillin
b) Tetracycline
c) Cephalosporin
, d) Erythromycin
Tetracyclines deposit in developing teeth and bones, causing
discoloration and growth inhibition.
9. Which drug is most effective for the management of acute angina?
a) Beta-blocker
b) Calcium channel blocker
c) Sublingual nitroglycerin
d) ACE inhibitor
Sublingual nitroglycerin rapidly relieves angina by vasodilation,
reducing myocardial oxygen demand.
10. What is the black box warning for fluoroquinolones?
a) Hepatotoxicity
b) Tendon rupture
c) Ototoxicity
d) Nephrotoxicity
Fluoroquinolones can cause tendon rupture, especially in older adults
and those on corticosteroids.
11. Which antihypertensive is preferred in African American patients
without CKD?
a) ACE inhibitors
b) Beta-blockers
c) Thiazide diuretics
d) ARBs
