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NURS 5315 Exam 1 (65 Questions) – Cellular Injury, Fluids & Electrolytes, Acid-Base, Genetics – UTA

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This document contains 65 expertly structured questions and answers for NURS 5315 – Pathophysiology at the University of Texas at Arlington (UTA) for the 2025/2026 academic year. It provides a complete review of essential pathophysiological concepts, including cellular adaptation and injury mechanisms (atrophy, hypertrophy, necrosis types, free radicals), fluid and electrolyte imbalances, acid-base disorders, oncology and metastasis pathways, and genetics (alleles, genotypes, inheritance patterns). Key topics include: Types and causes of necrosis (coagulative, liquefactive, fat, gangrenous) Metastatic vs dystrophic calcification Staging of cancer using the TNM system Fluid compartments and pressures (oncotic, hydrostatic, osmotic) Electrolyte shifts related to potassium, sodium, calcium, magnesium, and hormonal regulation (RAAS, ADH, natriuretic peptides) Detailed acid-base imbalances: metabolic and respiratory acidosis/alkalosis, with causes and compensatory mechanisms Basic genetic terminology and patterns of inheritance (dominant, recessive, codominance, sex-linked traits) This study resource is particularly valuable for: Nursing students in MSN, NP, or BSN bridge programs Pre-medical and Allied Health students studying advanced physiology and pathophysiology Physician Assistant (PA) students preparing for exam-based clinical application Presented in a straightforward Q&A format, this guide is ideal for mastering core exam topics, reinforcing clinical reasoning, and preparing for national certification boards. Keywords: NURS 5315, UTA, pathophysiology, cellular injury, atrophy, necrosis types, free radicals, inflammation, TNM staging, metastasis, electrolyte imbalances, fluid compartments, oncotic pressure, RAAS, ADH, acid base balance, metabolic acidosis, respiratory alkalosis, genetics, alleles, chromosomes

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Uploaded on
October 5, 2025
Number of pages
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Written in
2025/2026
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Nurs 5315 UTA Exam 1 2025/2026 Exam
Questions and Answers 100%
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Atrophy - 🧠 ANSWER ✔✔E. Cells decrease in size


P. Still functional

Physiologic: thymus gland in early childhood

Pathological: disuse


Hypertrophy - 🧠 ANSWER ✔✔E. Increase in cell size


P. Increased workload

Physiologic: weightlifting

Pathologic: cardiomegaly from HTN


Hyperplasia - 🧠 ANSWER ✔✔E. Increase in cell number


P. Increased cellular division

,Physiologic: liver regeneration

Pathologic: endometrial- usually r/t hormones


Dysplasia - 🧠 ANSWER ✔✔E. Cells change in size, shape, organization


P. AKA atypical hyperplasia, a disorderly proliferation

Physiologic: N/A

Pathologic: squamous dysplasia of cervix from HPV


Metaplasia - 🧠 ANSWER ✔✔E. one cell type replaced with another


P. reprogramming of stem cells, reversible

Physiologic: N/A

Pathologic: stratified squamous cells in bronchial lining r/t cigarette smoke


Hypoxia injury - 🧠 ANSWER ✔✔E. inadequate oxygenation of tissues


P. decrease in mitochondrial function, decreased production of ATP

increases anaerobic metabolism. eventual cell death.

C.M. hypoxia, cyanosis, cognitive impairment, lethargy

, Free radical and ROS - 🧠 ANSWER ✔✔E. normal byproduct of ATP

production, will overwhelm the mitochondria- exhaust intracellular

antioxidants

P. lipid peroxidation, damage proteins, fragment DNA

C.M. development in Alzheimer's, heart disease, Parkinson's disease,

Amyotrophic Lateral Sclerosis


Ethanol - 🧠 ANSWER ✔✔E. mood altering drug, long term effects on liver

and nutritional status

P. metabolized by liver, generates free radicals

C.M. CNS depression, nutrient deficiencies-Mag, Vit B6, thiamine, PO4,

inflammation and fatty infiltration of liver, hepatomegaly, leads to liver

failure irreversible


Oncosis - 🧠 ANSWER ✔✔Na and H2O enter cell and cause swelling.

Organ increases in weight, becomes distended and pale. Associated with

high fever, hypocalcemia, certain infections


Fatty Infiltration - 🧠 ANSWER ✔✔intracellular accumulation of lipids in the

liver



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