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TWU Concepts and Clinicals Exam 1 Questions And Answers Latest Updates 2026 With Correct Answers 100% With Complete Solutions Pass Guaranteed | Graded A+ |

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Colonization -presence and growth of microorganisms within a host may have no signs/symptoms Infection -germs are in or on the body and make you sick, which results in signs and symptoms such as fever, pus from a wound, a high white blood cell count, or pneumonia Communicable disease -is the infectious process transmitted from one person to another hand washing -most important technique to use in preventing and controlling transmission of infection Pt in all settings are at risk: -lower resistance -increased exposure -resistatce to antibiotics -invasive procedures Healthcare workers are at risk: -contact with pt blood and fluids -contact with contaminated equipment and surfaces Nature of Infection colonization vs. infection -disease or infection only result if the pathogens multiply and alter normal tissue function. Chain of Infection COI -Infectious agent or pathogen-Reservoir or source for pathogen growth -Portal of exit -Mode of transmission -Portal of entry -Susceptible host Infectious agent -bacteria, virus, fungi, protozoa -resident or transcient

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TWU Concepts and Clinicals Exam 1

Colonization
-presence and growth of microorganisms within a host > may have no
signs/symptoms

Infection
-germs are in or on the body and make you sick, which results in signs and
symptoms such as fever, pus from a wound, a high white blood cell count, or
pneumonia

Communicable disease
-is the infectious process transmitted from one person to another

hand washing
-most important technique to use in preventing and controlling transmission of
infection



Pt in all settings are at risk:
-lower resistance
-increased exposure
-resistatce to antibiotics
-invasive procedures

Healthcare workers are at risk:
-contact with pt blood and fluids
-contact with contaminated equipment and surfaces

Nature of Infection
colonization vs. infection
-disease or infection only result if the pathogens multiply and alter normal tissue
function.



Chain of Infection
COI
-Infectious agent or pathogen

,-Reservoir or source for pathogen growth
-Portal of exit
-Mode of transmission
-Portal of entry
-Susceptible host

Infectious agent
-bacteria, virus, fungi, protozoa
-resident or transcient

The potential for causing disease depends on:
-# of organisms
-virulence
-ability to enter and survive in host
-susceptibility of the host

reservoir
-place within which microorganisms can survive, multiply, and await transfer to a
susceptible host.
-HAI's

Common reservoirs for HAIs:
Healthcare workers
Patients
Equipment (eg. stethoscope)
Environment

to thrive, organisms require..
appropriate food, oxygen, water, temp, pH, light

Port of Exit
-after microorganisms find a site to grow and multiply, then must find a port of
exit if they are to enter another host and cause disease

Mode of transmission
-method of transfer by which the organism moves or is carried from one place to
another.
-unwashed hands

The major route of transmission for pathogens identified in the health care setting is
the unwashed hands of the health care worker.

,Hot spots for microorganism growth
Stethoscopes, hands, bedside commode, sinks, blood pressure cuff, IV poles, etc

Port of entry
-organisms enter the body through the same routes they use for exiting

Susceptible Host Risk factors
Nutritional status
Immunosuppression
Presence of chronic disease
Age

defenses against infection
Normal flora
-maintain sensitive balance with other microbes to prevent infection.
-releases antibacterial substances and inhibiting multiplication of pathogenic
microbes

Body system defenses
-organs have defense mechs specific to structure and function

inflammation
defensive protective reaction that delivers fluid, products, and nutrients to an area
of injury

Signs of localized inflammation -
redness, heat, swelling

Signs of systemic inflammation -
fever, malaise (if you don't fight infection can lead to organ failure)

HAIs
-infections that patients acquire within healthcare setting that result from
treatment for other conditions

Exogenous HAI
-from microorganisms outside the individual

Endogenous HAI
-when the patient's flora becomes altered and an overgrowth results
(eg. an antibiotic is taken and kills good bacteria, but then the patient is susceptible)

, HAI risk factors
Number of health care employees with direct contact with the patient
Types and numbers of invasive procedures
Therapy received
Length of hospitalization

Major sites for HAI & risks
Surgical or traumatic wounds
Urinary (catheter) and respiratory tracts
bloodstream

Antibiotic Resistant super bugs?
-MRSA, VRE, C. Diff

Asepsis
-absence of pathogenic microbes

aseptic technique
-practices/procedures that assist in reducing the risk for infection

medical asepsis
-clean technique, includes procedures for REDUCING the number of organisms
present and preventing the transfer of organisms

surgical asepsis
-sterile technique, includes practices used to render and keep objects and areas
free from microorganisms

Principles of surgical asepsis

1. A sterile object remains sterile only when touched by another sterile object.
2. Only sterile objects may be placed on a sterile field.
3. A sterile object or field out of the range of vision or an object held below a
person's waist is contaminated.
4. A sterile object or field becomes contaminated by prolonged exposure to
air.
5. When a sterile surface comes in contact with a wet, contaminated surface,
the sterile object or field becomes contaminated by capillary action.
6. Fluid flows in the direction of gravity.
7. The edges of a sterile field or container are considered to be contaminated.

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