University of Texas, Arlington NURS 5334;NURS5334 Cardiac Rx Case Lisinopril | Complete Grade Sheet/Rubric for Cardiac Rx Case Lisinopril | Latest Fall 2025.

Grade Sheet/Rubric for Pharmacology Case Studies

Student Name:

Part One [25 points]
Instructions Points
 Cite the drug and drug class that is the best choice for this patient at this time: X/15
Lisinopril; Angiotensin-Converting Enzyme inhibitor
https://www.epocrates.com/online/results?query=lisinopril
 Cite the name of the medicine you will prescribe and its MOA: X/9
Lisinopril: Reduces PVR without increasing cardiac output, heart rate, or contractibility;
blocks ACE, which converts angiotensin I to angiotensin II; prevents breakdown of
bradykinin, which increases NO and prostacyclin from vessels; NO and prostacyclin are
potent vasodilators of the arterioles and veins; By reducing levels of angiotensin II,
aldosterone levels are decreased, as is Na+ and water retention; ACEI reduce cardiac
preload and afterload
Parker, P. (2019). Cardiac and Renal Medications - Antihypertensives and Diuretics [PowerPoint slides]. UT Arlington.
Parker, P. (2019). Cardiac and Renal Medications - Antihypertensives and Diuretics Parts 1-2. Canvas Studio. UT Arlington
 If there was data from the patient’s history or exam that was relevant to choosing X/1
this agent, cite those here:
Jason has a 10+ year history of type 2 diabetes and 1+ proteinuria was present on
urinalysis which indicates early diabetic nephropathy. His BP was 145/85, which is not at
target on current medication amlodipine. ACE inhibitors are first-line agents for renal
protection in patients with diabetes, especially when proteinuria is present. They have been
proven to reduce intraglomerular pressure, decrease proteinuria, and slow progression of
kidney disease.
Parker, P. (2019). Cardiac and Renal Medications - Antihypertensives and Diuretics [PowerPoint slides]. UT Arlington.
Parker, P. (2019). Cardiac and Renal Medications - Antihypertensives and Diuretics Parts 1-2. Canvas Studio. UT Arlington


Part Two [35 points]
Instructions Points
 Labs/Diagnostics needed before starting this drug? Any ongoing lab monitoring or X/2
diagnostics need while the patient is on this medication?
BUN/Cr at baseline, then periodically, or more frequently if heart failure, renal artery
stenosis; electrolytes; BP; WBC if collagen vascular dz, especially if renal impairment
https://www.epocrates.com/online/drugs/1133/lisinopril#safety-monitoring
 Black Box Warning for this Medication? X/3
Fetal Toxicity: fetal/neonatal morbidity/mortality may occur when drugs that act directly
on the renin-angiotensin system are used in pregnancy; D/C drug ASAP once pregnancy
detected
https://www.epocrates.com/online/drugs/1133/lisinopril#black-box-warnings
 Contraindications? X/2
hypersensitivity to drug or ingredient; angioedema hx, ACE inhibitor-associated
hereditary & idiopathic angioedema; pregnancy; Many other cautions with this
medication. Please see link below:
https://www.epocrates.com/online/drugs/1133/lisinopril#contraindications-cautions
 ADEs X/10
anaphylactoid reaction; head, neck or intestinal angioedema; Stevens-Johnson syndrome;
toxic epidermal necrolysis; severe hypotension; hyperkalemia; renal impairment; renal
failure; hepatotoxicity; neutropenia; agranulocytosis; pancreatitis; SIADH
https://www.epocrates.com/online/drugs/1133/lisinopril#adverse-reactions
 Common Side Effects X/10
Dizziness; hypotension; BUN or Cr elevated; headache; hyperkalemia; URI; cough;
fatigue; abdominal pain; photosensitivity; hyperuricemia
https://www.epocrates.com/online/drugs/1133/lisinopril#adverse-reactions


 Specific education/counseling that should be done for this patient at this time? X/2

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