TestBank-FocusonNursingPharmacology(8thEditionbyKarch) 1
TableofContents
h h
TableofContents
h h 1
Chapter01-IntroductiontoDrugs 3
Chapter02-DrugsandtheBody
h 20
Chapter03-ToxicEffectsofDrugs
h 37
Chapter04-TheNursingProcessinDrugTherapyandPatientSafety b 54
hChapter05-DosageCalculations 71
Chapter06-ChallengestoEffectiveDrugTherapy 86
Chapter07-IntroductiontoCellPhysiology Chapter
h h 103
08-AntiinfectiveAgents
h 120
Chapter09-AntibioticsChapter 138
10-AntiviralAgentsChapter11-
h 155
AntifungalAgents
h 172
Chapter12-AntiprotozoalAgents 188
Chapter13-AnthelminticAgentsChapter
h 204
14-AntineoplasticAgents 220
Chapter15-IntroductiontotheImmuneResponseandInflammation 237
hChapter16-Antiinflammatory,Antiarthritis,andRelatedAgentsChapter17 254
-ImmuneModulators 270
Chapter18-VaccinesandSera
h h h h h 287
Chapter19-IntroductiontoNervesandtheNervousSystem 304
hChapter20-AnxiolyticandHypnoticAgents 320
Chapter21-Antidepressant Agents b 337
Chapter22-PsychotherapeuticAgents
h 354
Chapter23-AntiseizureAgents Chapter
h h 371
24-AntiparkinsonismAgentsChapter25
h h
388
-MuscleRelaxants 404
Chapter26-Narcotics,NarcoticAntagonists,andAntimigraineAgents 420
hChapter27-GeneralandLocalAnestheticAgents 436
Chapter28-NeuromuscularJunctionBlockingAgentsChapter 453
29-IntroductiontotheAutonomicNervousSystemChapter30-
h 470
AdrenergicAgonists
h
487
Chapter31-AdrenergicAntagonists h 503
Chapter32-CholinergicAgonists
h h 520
Chapter33-AnticholinergicAgents
h
536
Chapter34-IntroductiontotheEndocrineSystem 553
Chapter35-HypothalamicandPituitaryAgents
h
569
Chapter36-AdrenocorticalAgents
h
585
Chapter 37 - Thyroid and Parathyroid AgentsChapter 38-
h h h h h h h h
602
AgentstoControlBloodGlucoseLevelsChapter 39- h h
619
Introduction to the Reproductive System
h h h h h
636
Chapter40-DrugsAffectingtheFemaleReproductiveSystem 653
Chapter41-DrugsAffectingtheMaleReproductiveSystem
h
669
Chapter42-IntroductiontotheCardiovascularSystem Chapter
h h
685
43-DrugsAffectingBloodPressure
h
702
Chapter44-AgentsforTreatingHeartFailureChapter 719
45-AntiarrhythmicAgents
h
735
Chapter46-AntianginalAgentsChapter h
752
47-Lipid-LoweringAgents
h
768
Chapter48-DrugsAffectingBloodCoagulation 785
Chapter49-DrugsUsedtoTreatAnemiasChapter50
h
801
-IntroductiontotheRenalSystem 817
,TestBank-FocusonNursingPharmacology(8thEditionbyKarch) 2
Chapter51-DiureticAgents
h h h h 833
Chapter52-DrugsAffectingtheUrinaryTractandtheBladder 849
Chapter53-IntroductiontotheRespiratorySystem
h 866
Chapter54-DrugsActingontheUpperRespiratoryTract 883
Chapter55-DrugsActingontheLowerRespiratoryTract
h 900
Chapter56-IntroductiontotheGastrointestinalSystem
h 917
Chapter57-DrugsAffectingGastrointestinalSecretions
h 933
Chapter58-DrugsAffectingGastrointestinalMotilityChapter
h h 949
59-AntiemeticAgents
h 965
,TestBank-FocusonNursingPharmacology(8thEditionbyKarch) 3
Chapter01-IntroductiontoDrugs
h h h h h
1. Anurseworkinginradiologyadministersiodinetoapatientwhoishavingacomputed tomography(CT) b b b h
hscan.Thenurseworkingontheoncologyunitadministerschemotherapytopatientswhohavecancer.Atthe
b b b h
hPublicHealthDepartment,anurseadministersameasles-mumps-rubella(MMR)vaccinetoa14-month-
b b h
holdchildasaroutineimmunization.Whichbranchofpharmacologybestdescribestheactionsofallthree
b b b b h
hnurses?
A) Pharmacoeconomics
B) Pharmacotherapeutics
C) Pharmacodynamics
D) Pharmacokinetics
Ans: B
Feedback:
Pharmacologyis thestudyofthebiologiceffectsofchemicals.Nursesareinvolvedwithclinical
b h b
pharmacologyorpharmacotherapeutics,whichisabranchofpharmacologythatdealswith theusesofdrugsto
h b b b h
treat,prevent,anddiagnosedisease.Theradiologynurseisadministeringadrugtohelpdiagnoseadisease.
h b
Theoncologynurseisadministeringadrugtohelptreatadisease. b b
Pharmacoeconomicsincludesanycosts involvedindrugtherapy.Pharmacodynamicsinvolveshowadrug
b b h
affectsthebodyandpharmacokineticsishowthebodyactsonthebody.
h b
2. Aphysicianhas ordered intramuscular(IM)injectionsofmorphine,anarcotic,every4hoursasneededforpain
b b b h h
ina motorvehicleaccidentvictim.Thenurseisawarethisdrughasa highabusepotential. Underwhat category
h bh b h b
wouldmorphinebeclassified?
h
A) Schedule I h
B) Schedule II h
C) Schedule III h
D) Schedule IV h
Ans: B
Feedback:
NarcoticswithahighabusepotentialareclassifiedasScheduleIIdrugsbecauseofseveredependence
h h h h h h h h h h h h h h h
, TestBank-FocusonNursingPharmacology(8thEditionbyKarch) 4
liability. Schedule I drugs have high abuse potential and no accepted medical use. Schedule III drugs have a lesser
h h h h h h h h h h h h h h h h h h
abuse potential than II and an accepted medical use. Schedule IV drugs have low abuse potential and
h h h h h h h h h h h h h h h h h
limited dependenceliability.
h b
3. WheninvolvedinphaseIIIdrugevaluationstudies,whatresponsibilitieswouldthenursehave?
h h h h h h h h h h h h h
A) Workingwithanimalswhoaregivenexperimentaldrugs
h h h h h h h
B) Choosingappropriatepatientstobeinvolvedinthedrugstudy
h h h h h h h h h
C) Monitoringandobservingpatientscloselyforadverseeffects h h h h h h h
D) Conducting researchtodetermineeffectivenessofthedrugAns: b b
h C
Feedback:
PhaseIIIstudiesinvolveuseofadruginavastclinicalpopulationinwhichpatientsareaskedtorecordany b h h
hsymptoms they experience while taking the drugs. Nurses may be responsible for helping collectand
h h h h h h h h h h h h h
analyzetheinformationtobesharedwiththeFoodandDrugAdministration(FDA)butwould notconduct
h b b b b h
hresearchindependentlybecausenursesdonotprescribemedications.Use ofanimalsindrugtesting is done in b b h h h
hthe preclinical trials. Select patients who are involved in phase II studies to participatein studieswherethe
h h h h h h h h h h h h h b
participantshavethediseasethedrugisintended totreat.Thesepatients are monitoredcloselyfordrug action
h b b h b
handadverseeffects.PhaseIstudies involvehealthyhumanvolunteerswhoareusuallypaidfortheirparticipation. b b b h
hNursesmayobserveforadverseeffectsandtoxicity.
4. What conceptisconsideredwhengenericdrugsaresubstitutedforbrandnamedrugs?
bh h h h h h h h h h h h
A) Bioavailability
B) Criticalconcentration h
C) Distribution
D) Half-life
Ans: A
Feedback:
Bioavailabilityistheportionofadoseofadrugthatreachesthesystemiccirculationandisavailabletoacton b b h h
hbodycells.Bindersusedinagenericdrugmaynotbethesameasthoseusedinthebrandnamedrug.Therefore, h
hthewaythebodybreaksdown andusesthedrugmaydiffer,whichmayeliminateagenericdrug substitution. b b b h
hCriticalconcentrationistheamountofa drugthat isneeded tocauseatherapeutic effect and should not differ b bh b h h h h h
hbetween generic and brand name medications. Distribution isthe phase of pharmacokinetics, which involves
h h h h h h h h h h h h
the movement of a drug to the body’s tissues and is the
h h h h h h h h h h h h
TableofContents
h h
TableofContents
h h 1
Chapter01-IntroductiontoDrugs 3
Chapter02-DrugsandtheBody
h 20
Chapter03-ToxicEffectsofDrugs
h 37
Chapter04-TheNursingProcessinDrugTherapyandPatientSafety b 54
hChapter05-DosageCalculations 71
Chapter06-ChallengestoEffectiveDrugTherapy 86
Chapter07-IntroductiontoCellPhysiology Chapter
h h 103
08-AntiinfectiveAgents
h 120
Chapter09-AntibioticsChapter 138
10-AntiviralAgentsChapter11-
h 155
AntifungalAgents
h 172
Chapter12-AntiprotozoalAgents 188
Chapter13-AnthelminticAgentsChapter
h 204
14-AntineoplasticAgents 220
Chapter15-IntroductiontotheImmuneResponseandInflammation 237
hChapter16-Antiinflammatory,Antiarthritis,andRelatedAgentsChapter17 254
-ImmuneModulators 270
Chapter18-VaccinesandSera
h h h h h 287
Chapter19-IntroductiontoNervesandtheNervousSystem 304
hChapter20-AnxiolyticandHypnoticAgents 320
Chapter21-Antidepressant Agents b 337
Chapter22-PsychotherapeuticAgents
h 354
Chapter23-AntiseizureAgents Chapter
h h 371
24-AntiparkinsonismAgentsChapter25
h h
388
-MuscleRelaxants 404
Chapter26-Narcotics,NarcoticAntagonists,andAntimigraineAgents 420
hChapter27-GeneralandLocalAnestheticAgents 436
Chapter28-NeuromuscularJunctionBlockingAgentsChapter 453
29-IntroductiontotheAutonomicNervousSystemChapter30-
h 470
AdrenergicAgonists
h
487
Chapter31-AdrenergicAntagonists h 503
Chapter32-CholinergicAgonists
h h 520
Chapter33-AnticholinergicAgents
h
536
Chapter34-IntroductiontotheEndocrineSystem 553
Chapter35-HypothalamicandPituitaryAgents
h
569
Chapter36-AdrenocorticalAgents
h
585
Chapter 37 - Thyroid and Parathyroid AgentsChapter 38-
h h h h h h h h
602
AgentstoControlBloodGlucoseLevelsChapter 39- h h
619
Introduction to the Reproductive System
h h h h h
636
Chapter40-DrugsAffectingtheFemaleReproductiveSystem 653
Chapter41-DrugsAffectingtheMaleReproductiveSystem
h
669
Chapter42-IntroductiontotheCardiovascularSystem Chapter
h h
685
43-DrugsAffectingBloodPressure
h
702
Chapter44-AgentsforTreatingHeartFailureChapter 719
45-AntiarrhythmicAgents
h
735
Chapter46-AntianginalAgentsChapter h
752
47-Lipid-LoweringAgents
h
768
Chapter48-DrugsAffectingBloodCoagulation 785
Chapter49-DrugsUsedtoTreatAnemiasChapter50
h
801
-IntroductiontotheRenalSystem 817
,TestBank-FocusonNursingPharmacology(8thEditionbyKarch) 2
Chapter51-DiureticAgents
h h h h 833
Chapter52-DrugsAffectingtheUrinaryTractandtheBladder 849
Chapter53-IntroductiontotheRespiratorySystem
h 866
Chapter54-DrugsActingontheUpperRespiratoryTract 883
Chapter55-DrugsActingontheLowerRespiratoryTract
h 900
Chapter56-IntroductiontotheGastrointestinalSystem
h 917
Chapter57-DrugsAffectingGastrointestinalSecretions
h 933
Chapter58-DrugsAffectingGastrointestinalMotilityChapter
h h 949
59-AntiemeticAgents
h 965
,TestBank-FocusonNursingPharmacology(8thEditionbyKarch) 3
Chapter01-IntroductiontoDrugs
h h h h h
1. Anurseworkinginradiologyadministersiodinetoapatientwhoishavingacomputed tomography(CT) b b b h
hscan.Thenurseworkingontheoncologyunitadministerschemotherapytopatientswhohavecancer.Atthe
b b b h
hPublicHealthDepartment,anurseadministersameasles-mumps-rubella(MMR)vaccinetoa14-month-
b b h
holdchildasaroutineimmunization.Whichbranchofpharmacologybestdescribestheactionsofallthree
b b b b h
hnurses?
A) Pharmacoeconomics
B) Pharmacotherapeutics
C) Pharmacodynamics
D) Pharmacokinetics
Ans: B
Feedback:
Pharmacologyis thestudyofthebiologiceffectsofchemicals.Nursesareinvolvedwithclinical
b h b
pharmacologyorpharmacotherapeutics,whichisabranchofpharmacologythatdealswith theusesofdrugsto
h b b b h
treat,prevent,anddiagnosedisease.Theradiologynurseisadministeringadrugtohelpdiagnoseadisease.
h b
Theoncologynurseisadministeringadrugtohelptreatadisease. b b
Pharmacoeconomicsincludesanycosts involvedindrugtherapy.Pharmacodynamicsinvolveshowadrug
b b h
affectsthebodyandpharmacokineticsishowthebodyactsonthebody.
h b
2. Aphysicianhas ordered intramuscular(IM)injectionsofmorphine,anarcotic,every4hoursasneededforpain
b b b h h
ina motorvehicleaccidentvictim.Thenurseisawarethisdrughasa highabusepotential. Underwhat category
h bh b h b
wouldmorphinebeclassified?
h
A) Schedule I h
B) Schedule II h
C) Schedule III h
D) Schedule IV h
Ans: B
Feedback:
NarcoticswithahighabusepotentialareclassifiedasScheduleIIdrugsbecauseofseveredependence
h h h h h h h h h h h h h h h
, TestBank-FocusonNursingPharmacology(8thEditionbyKarch) 4
liability. Schedule I drugs have high abuse potential and no accepted medical use. Schedule III drugs have a lesser
h h h h h h h h h h h h h h h h h h
abuse potential than II and an accepted medical use. Schedule IV drugs have low abuse potential and
h h h h h h h h h h h h h h h h h
limited dependenceliability.
h b
3. WheninvolvedinphaseIIIdrugevaluationstudies,whatresponsibilitieswouldthenursehave?
h h h h h h h h h h h h h
A) Workingwithanimalswhoaregivenexperimentaldrugs
h h h h h h h
B) Choosingappropriatepatientstobeinvolvedinthedrugstudy
h h h h h h h h h
C) Monitoringandobservingpatientscloselyforadverseeffects h h h h h h h
D) Conducting researchtodetermineeffectivenessofthedrugAns: b b
h C
Feedback:
PhaseIIIstudiesinvolveuseofadruginavastclinicalpopulationinwhichpatientsareaskedtorecordany b h h
hsymptoms they experience while taking the drugs. Nurses may be responsible for helping collectand
h h h h h h h h h h h h h
analyzetheinformationtobesharedwiththeFoodandDrugAdministration(FDA)butwould notconduct
h b b b b h
hresearchindependentlybecausenursesdonotprescribemedications.Use ofanimalsindrugtesting is done in b b h h h
hthe preclinical trials. Select patients who are involved in phase II studies to participatein studieswherethe
h h h h h h h h h h h h h b
participantshavethediseasethedrugisintended totreat.Thesepatients are monitoredcloselyfordrug action
h b b h b
handadverseeffects.PhaseIstudies involvehealthyhumanvolunteerswhoareusuallypaidfortheirparticipation. b b b h
hNursesmayobserveforadverseeffectsandtoxicity.
4. What conceptisconsideredwhengenericdrugsaresubstitutedforbrandnamedrugs?
bh h h h h h h h h h h h
A) Bioavailability
B) Criticalconcentration h
C) Distribution
D) Half-life
Ans: A
Feedback:
Bioavailabilityistheportionofadoseofadrugthatreachesthesystemiccirculationandisavailabletoacton b b h h
hbodycells.Bindersusedinagenericdrugmaynotbethesameasthoseusedinthebrandnamedrug.Therefore, h
hthewaythebodybreaksdown andusesthedrugmaydiffer,whichmayeliminateagenericdrug substitution. b b b h
hCriticalconcentrationistheamountofa drugthat isneeded tocauseatherapeutic effect and should not differ b bh b h h h h h
hbetween generic and brand name medications. Distribution isthe phase of pharmacokinetics, which involves
h h h h h h h h h h h h
the movement of a drug to the body’s tissues and is the
h h h h h h h h h h h h
