NR 546 FINAL PRACTICE EXAM
PSYCHOPHARMACOLOGY|QUESTIONS AND
100% CORRECT AND WELL DETAILED
ANSWERS|LATEST 2025/2026|GUARANTEED
MAOIs (monoamine oxidase inhibitors) affect which neurotransmitters?
B B B B B B
A. Serotonin, Dopamine, Norepinephrine
B B B
B. Serotonin, GABA, Glutamate
B B B
C. Acetylcholine, Dopamine, Norepinephrine
B B B
D. Dopamine, GABA, Acetylcholine - ANSWER
B B B B B A. Serotonin, Dopamine, Norepinephrine
B B B
Which of the following is considered first line treatment for depression?
B B B B B B B B B B
A. SSRI
B
B. FGA
B
C. SNRI
B
D. MAOI - ANSWER
B B B A. SSRI
B
When treating a patient for major depression disorder which medication would the PMHNP c
B B B B B B B B B B B B B
onsider first?B
A. Depakote
B
B. Selegiline
B
C. Escitalopram
B
D. Isocarboxazid - ANSWER
B B B C. Escitalopram
B
1
,Which of the following medication should be considered for a patient diagnosed with major d
B B B B B B B B B B B B B B
epressive disorder who reports "always forgetting to take my pills"?
B B B B B B B B B
A. Mirtazapine
B
B. Fluvoxamine
B
C. Fluoxetine
B
D. Carbemazepine - ANSWER
B B B C. Fluoxetine
B
Which of the following medication has a black box warning of a life-threatening skin rash?
B B B B B B B B B B B B B B
A. Lithium
B
B. Lamotrigine
B
C. Lurasidone
B
D. Lorazepam - ANSWER
B B B B. Lamotrigine
B
Which medication is considered the best tolerated SSRI?
B B B B B B B
A. Venlafaxine
B
B. Bupropion
B
C. Setraline
B
D. Escitalopram - ANSWER
B B B D. Escitalopram
B
During a 4 week follow up appointment, Rashida, who is prescribed Sertraline 25mg qAM rep
B B B B B B B B B B B B B B
orts slight improvement in depression symptoms and tolerating medication well. Which of the
B B B B B B B B B B B B
following should the PMHNP do?
B B B B B
A. Increase Setraline dose
B B B
B. Switch to an SNRI
B B B B
2
, C. Switch to a different SSRI
B B B B B
D. Add Trazodone qHS for sleep. - ANSWER
B B B B B B B A. Increase Setraline dose
B B B
Which medication should be avoided for the 66 year patient diagnosed with major depressive
B B B B B B B B B B B B B B
disorder and anxiety with a reported fall 3 months ago?
B B B B B B B B B
A. Citalopram
B
B. Setraline
B
C. Paroxetine
B B
D. Aripiprazole - ANSWER
B B B C. Paroxetine
B
A patient reports upset stomach and diarrhea 3 days after taking new prescription of sertralin
B B B B B B B B B B B B B B
e. Which of the following is the most appropriate response from the PMHNP?
B B B B B B B B B B B B
A. "Start doubling the dose of sertraline and your symptoms will begin to ease up".
B B B B B B B B B B B B B B B
B. "Most side effects subside after 4-
B B B B B B
5 days. Your body is getting adjusted to the increased serotonin levels".
B B B B B B B B B B B
C. "Stop taking it immediately and go to the local emergency department".
B B B B B B B B B B B
D. "You must take Sertraline with food, otherwise you will continue to experience GI symptom
B B B B B B B B B B B B B B
s". - ANSWER
B B B. "Most side effects subside after 4- B B B B B B
5 days. Your body is getting adjusted to the increased serotonin levels".
B B B B B B B B B B B
During a 2 week follow up appointment, the patient reports no improvement in depressive sy
B B B B B B B B B B B B B B
mptoms with escitalopram. Which of the following statement made by the PMHNP is correct?
B B B B B B B B B B B B B
A. "Let's discontinue escitalopram and start you on something stronger".
B B B B B B B B B
B. "It can take up to 6 weeks before you notice improvements of depressive symptoms".
B B B B B B B B B B B B B B B
C. "I am going to prescibe Trazodone. Take it at night to help you sleep".
B B B B B B B B B B B B B B
3
PSYCHOPHARMACOLOGY|QUESTIONS AND
100% CORRECT AND WELL DETAILED
ANSWERS|LATEST 2025/2026|GUARANTEED
MAOIs (monoamine oxidase inhibitors) affect which neurotransmitters?
B B B B B B
A. Serotonin, Dopamine, Norepinephrine
B B B
B. Serotonin, GABA, Glutamate
B B B
C. Acetylcholine, Dopamine, Norepinephrine
B B B
D. Dopamine, GABA, Acetylcholine - ANSWER
B B B B B A. Serotonin, Dopamine, Norepinephrine
B B B
Which of the following is considered first line treatment for depression?
B B B B B B B B B B
A. SSRI
B
B. FGA
B
C. SNRI
B
D. MAOI - ANSWER
B B B A. SSRI
B
When treating a patient for major depression disorder which medication would the PMHNP c
B B B B B B B B B B B B B
onsider first?B
A. Depakote
B
B. Selegiline
B
C. Escitalopram
B
D. Isocarboxazid - ANSWER
B B B C. Escitalopram
B
1
,Which of the following medication should be considered for a patient diagnosed with major d
B B B B B B B B B B B B B B
epressive disorder who reports "always forgetting to take my pills"?
B B B B B B B B B
A. Mirtazapine
B
B. Fluvoxamine
B
C. Fluoxetine
B
D. Carbemazepine - ANSWER
B B B C. Fluoxetine
B
Which of the following medication has a black box warning of a life-threatening skin rash?
B B B B B B B B B B B B B B
A. Lithium
B
B. Lamotrigine
B
C. Lurasidone
B
D. Lorazepam - ANSWER
B B B B. Lamotrigine
B
Which medication is considered the best tolerated SSRI?
B B B B B B B
A. Venlafaxine
B
B. Bupropion
B
C. Setraline
B
D. Escitalopram - ANSWER
B B B D. Escitalopram
B
During a 4 week follow up appointment, Rashida, who is prescribed Sertraline 25mg qAM rep
B B B B B B B B B B B B B B
orts slight improvement in depression symptoms and tolerating medication well. Which of the
B B B B B B B B B B B B
following should the PMHNP do?
B B B B B
A. Increase Setraline dose
B B B
B. Switch to an SNRI
B B B B
2
, C. Switch to a different SSRI
B B B B B
D. Add Trazodone qHS for sleep. - ANSWER
B B B B B B B A. Increase Setraline dose
B B B
Which medication should be avoided for the 66 year patient diagnosed with major depressive
B B B B B B B B B B B B B B
disorder and anxiety with a reported fall 3 months ago?
B B B B B B B B B
A. Citalopram
B
B. Setraline
B
C. Paroxetine
B B
D. Aripiprazole - ANSWER
B B B C. Paroxetine
B
A patient reports upset stomach and diarrhea 3 days after taking new prescription of sertralin
B B B B B B B B B B B B B B
e. Which of the following is the most appropriate response from the PMHNP?
B B B B B B B B B B B B
A. "Start doubling the dose of sertraline and your symptoms will begin to ease up".
B B B B B B B B B B B B B B B
B. "Most side effects subside after 4-
B B B B B B
5 days. Your body is getting adjusted to the increased serotonin levels".
B B B B B B B B B B B
C. "Stop taking it immediately and go to the local emergency department".
B B B B B B B B B B B
D. "You must take Sertraline with food, otherwise you will continue to experience GI symptom
B B B B B B B B B B B B B B
s". - ANSWER
B B B. "Most side effects subside after 4- B B B B B B
5 days. Your body is getting adjusted to the increased serotonin levels".
B B B B B B B B B B B
During a 2 week follow up appointment, the patient reports no improvement in depressive sy
B B B B B B B B B B B B B B
mptoms with escitalopram. Which of the following statement made by the PMHNP is correct?
B B B B B B B B B B B B B
A. "Let's discontinue escitalopram and start you on something stronger".
B B B B B B B B B
B. "It can take up to 6 weeks before you notice improvements of depressive symptoms".
B B B B B B B B B B B B B B B
C. "I am going to prescibe Trazodone. Take it at night to help you sleep".
B B B B B B B B B B B B B B
3