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What class of medication can cause tooth discoloration, deposits on bones,
and bone growth restriction? - 🧠 ANSWER ✔✔Tetracycline antibiotics
What are the risks to a postpartum mother and newborn if the mother is an
ultra-rapid metabolizer taking codeine? - 🧠 ANSWER ✔✔opioid toxicity
*in ultrarapid metabolizers, there may be an increase in morphine from
codeine, resulting in opioid toxicity.
Combined oral contraceptives increase blood levels of
_____________________, _____________________, _______________,
and ________________. - 🧠 ANSWER ✔✔theophylline
,valium
TCA's
Lithium
Grapefruit juice is a CYP450 ____________, and leads to
______________ pharmacologic effect of drugs. - 🧠 ANSWER ✔✔inhibitor
increased
What electrolyte do you need to monitor while a patient is taking
Drospirenone (COC)? - 🧠 ANSWER ✔✔Potassium
It also interacts with other K+ sparing drugs, causing hyperkalemia (ACEi,
ARBs, K+ sparin diuretics, NSAIDs)
Iron supplementation is contraindicated in whom? - 🧠 ANSWER ✔✔children
<6 years
overdose is fatal
What are the risks to a pregnant woman who takes an NSAID? (2 listed) - 🧠
ANSWER ✔✔Hypertension
,bleeding at delivery
What are the risks to a fetus if the mother takes an NSAID? (2 listed) - 🧠
ANSWER ✔✔premature closure of DA
may cause GI bleeds
Probiotic use is contraindicated in whom? - 🧠 ANSWER
✔✔immunocompromised individuals
What fatal rhythm is the risk when taking a medication that causes a QT
prolongation? - 🧠 ANSWER ✔✔torsades
T/F: A 30-year old woman with hyperlipidemia can safely continue to take
her statin when pregnant. - 🧠 ANSWER ✔✔False
*Statins are teratogenic in pregnancy
Excessive intake of what vitamin is teratogenic in pregnancy? - 🧠 ANSWER
✔✔Vitamin A/Retinoic Acid
What is the black box warning for fluoroquinolones? - 🧠 ANSWER
✔✔tendon rupture
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3
, fluoroquinolones should not be prescribed for patients with peripheral
atherosclerotic vascular disease, HTN, Marfan's syndrome and the elderly
d/t the increased risk of what? - 🧠 ANSWER ✔✔aortic aneurysm
Clarithromycin (Biaxin) should not be taken with what two HMG-CoA
reductase inhibitors (statins)? - 🧠 ANSWER ✔✔lovastatin
simvastatin
Live vaccines are contraindicated in ___________, children <______ years
old, and _____________________ individuals. - 🧠 ANSWER ✔✔pregnancy
children <12 years old
immunocompromised
Clients at high risk for low B6 (HIV, DM, RF, Alcoholics, pregnant/lactating
women) should take supplemental vitamin B6 when taking what drug? - 🧠
ANSWER ✔✔Isoniazid (INH)
* also need backup contraceptive while using INH
When taking Isoniazid (INH), patients at risk of what vitamin deficiency
should supplement with it? - 🧠 ANSWER ✔✔B6