FL 5 AAMC MCAT EXAM LATEST 2025-2026 ACTUAL
EXAM ALL 100 QUESTIONS AND CORRECT
DETAILED ANSWERS (VERIFIED ANSWERS)
|ALREADY GRADED A+
✅ Key Features:
100 exam-style practice questions with correct answers and detailed
explanations.
Covers core MCAT subjects including biochemistry, general chemistry,
physics, biology, psychology, sociology, and critical analysis and
reasoning skills (CARS).
Rationales clarify why answers are correct and explain related concepts for
deeper understanding.
Structured to enhance critical thinking, problem-solving, and test-taking
strategies.
Suitable for self-study, group review, or instructor-led practice sessions.
🎯 Best For:
Pre-med students preparing for the AAMC MCAT Full-Length 5 (FL 5)
exam.
Learners seeking practice questions with detailed rationales to reinforce
mastery of concepts.
Instructors and study groups needing a structured MCAT prep resource.
Students aiming to strengthen knowledge, reasoning, and exam
confidence.
Based on Figure 1, which patient is LEAST likely to benefit from therapy with immunosuppressors? A
patient whose transplanted kidneys are associated with miRNA expression patterns characterized by: A.
high levels of miR-155
B. low levels of let-7c.
C. high levels of miR-30a-3p.
D. low levels of miR-10b. - ANSWER-C.
,Least likely to benefit from therapy with immunosuppressors are patients that high levels of miRNA
levels in normal transplant, and low levels in acute rejection, as suppressing these high levels will tend to
cause acute rejection instead. The only item that is this is miR-30a-3p due to high levels for normal and
low levels for acute rejection
[Incorrect - Simply counted wrong, as my eyesight is bloodshot during these exams :(]
Question 3 - Passage 1
The arrow in the graph indicates the curve representing the melting temperature for which miRNA,
assuming 100% base complementarity with its target sequence?
A. miR-142-5p
B. miR-223 C. miR-10b
D. miR-30a-3p - ANSWER-D.
To have the lowest level of denaturation at the most extreme temperature means the Tm level for the
miRNA sequence must be abruptly high, this is only capable with additional hydrogen bonds to stabilize
the structure, therefore G-C bond should be more plentiful and present to increase the Tm levels, and D
has 11 G-C bonds compared to C which has only 10 G-C bonds
[Flagged - Used process of elimination and this was my final answer left so not completely sure]
Question 5 - Passage 2
From Table 1, which bacteria can use galactose as an energy source?
A. Ruminococcus
B. Faecalibacterium
C. Odoribacter
D. Phascolactobacterium - ANSWER-C.
The table states that Odoribacter uses glucose and its isomers for an energy source. Glucose and its
isomers are: Glucose, fructose, and galactose.
[Flagged - Was slightly confused between C and D, and went with D as it seemed the most reasonable]
,Question 12
In contrast to chemical messengers in classical endocrine signaling systems, chemical messengers in
paracrine and autocrine signaling systems are: A. secreted by neurons only.
B. not likely to bind cell receptors.
C. usually transported by ducts.
D. not transported by blood vessels. - ANSWER-D.
Endocrine:
- Signals are released into the blood in order to impact tissues scattered throughout the body
Paracrine and Autocrine:
- Act locally
- Paracrine Messengers act on cells near the cell that secrete the messenger
- Autocrine Messengers act on the same cell that secretes the messenger
- Are not transported by blood vessels
[Flagged - Stuck between A and D, and went with A as I could reason out in my head made the most
sense]
Question 15 - Passage 3
An increase in which of the following physiological variables is most likely to cause an increase in the
amount of EPO released by the kidneys in a healthy human adult?
A. Amount of aerobic exercise the person performs
B. Total amount of circulating hemoglobin
C. Rate of erythrocyte maturation
D. Cardiac output (volume of blood pumped by the heart per minute) - ANSWER-A.
EPO is produced in response to low tissue levels of oxygen, and causes the formation of RBCs.
When the amount of aerobic exercises increases, the person demand for oxygen increases as their
oxygen levels decrease, causing an increase in the amount of EPO released by the kidneys
D: Cardiac output would not directly affect EPO levels but heart rate might
, [Incorrect - Stuck between B and C, and simply didn't catch the mistake in B and C seemed too good]
Question 16 - Passage 3
Interested in developing ways to treat human strokes, researchers are attempting to develop forms of
EPO that act on CNS neurons without affecting erythrocyte production in the bone marrow. One benefit
of such a form of EPO in stroke treatment would be to:
A. promote apoptosis of damaged CNS neurons without affecting blood oxygen levels.
B. limit neuronal cell death without causing an immediate decrease in the oxygen-carrying capacity of
the blood.
C. prevent apoptosis in the CNS without causing a harmful increase in blood viscosity.
D. promote healing in the CNS without increasing the risk of developing tumors. - ANSWER-C.
2x2 question:
- The first major part was tackling that benefit of EPO was that it prevents apoptosis
- The other was noticing that it mentioned angiogenesis which means that it increases the
oxygencarrying capacity of the blood due to supporting more forms of oxygenated blood transport
- Therefore only C would be left, which makes sense as no major increase in blood viscosity would be
ideal to treat a stroke victim.
[Flagged - Said cytosol and then released that it was a glycoprotein and not a steroid]
Question 19 - Passage 3
In which of the following cellular locations does EPO most likely initially bind EPOR in erythrocyte
precursor cells?
A. Cytosol
B. Endoplasmic reticulum
C. Nucleus
D. Plasma membrane - ANSWER-D.
EXAM ALL 100 QUESTIONS AND CORRECT
DETAILED ANSWERS (VERIFIED ANSWERS)
|ALREADY GRADED A+
✅ Key Features:
100 exam-style practice questions with correct answers and detailed
explanations.
Covers core MCAT subjects including biochemistry, general chemistry,
physics, biology, psychology, sociology, and critical analysis and
reasoning skills (CARS).
Rationales clarify why answers are correct and explain related concepts for
deeper understanding.
Structured to enhance critical thinking, problem-solving, and test-taking
strategies.
Suitable for self-study, group review, or instructor-led practice sessions.
🎯 Best For:
Pre-med students preparing for the AAMC MCAT Full-Length 5 (FL 5)
exam.
Learners seeking practice questions with detailed rationales to reinforce
mastery of concepts.
Instructors and study groups needing a structured MCAT prep resource.
Students aiming to strengthen knowledge, reasoning, and exam
confidence.
Based on Figure 1, which patient is LEAST likely to benefit from therapy with immunosuppressors? A
patient whose transplanted kidneys are associated with miRNA expression patterns characterized by: A.
high levels of miR-155
B. low levels of let-7c.
C. high levels of miR-30a-3p.
D. low levels of miR-10b. - ANSWER-C.
,Least likely to benefit from therapy with immunosuppressors are patients that high levels of miRNA
levels in normal transplant, and low levels in acute rejection, as suppressing these high levels will tend to
cause acute rejection instead. The only item that is this is miR-30a-3p due to high levels for normal and
low levels for acute rejection
[Incorrect - Simply counted wrong, as my eyesight is bloodshot during these exams :(]
Question 3 - Passage 1
The arrow in the graph indicates the curve representing the melting temperature for which miRNA,
assuming 100% base complementarity with its target sequence?
A. miR-142-5p
B. miR-223 C. miR-10b
D. miR-30a-3p - ANSWER-D.
To have the lowest level of denaturation at the most extreme temperature means the Tm level for the
miRNA sequence must be abruptly high, this is only capable with additional hydrogen bonds to stabilize
the structure, therefore G-C bond should be more plentiful and present to increase the Tm levels, and D
has 11 G-C bonds compared to C which has only 10 G-C bonds
[Flagged - Used process of elimination and this was my final answer left so not completely sure]
Question 5 - Passage 2
From Table 1, which bacteria can use galactose as an energy source?
A. Ruminococcus
B. Faecalibacterium
C. Odoribacter
D. Phascolactobacterium - ANSWER-C.
The table states that Odoribacter uses glucose and its isomers for an energy source. Glucose and its
isomers are: Glucose, fructose, and galactose.
[Flagged - Was slightly confused between C and D, and went with D as it seemed the most reasonable]
,Question 12
In contrast to chemical messengers in classical endocrine signaling systems, chemical messengers in
paracrine and autocrine signaling systems are: A. secreted by neurons only.
B. not likely to bind cell receptors.
C. usually transported by ducts.
D. not transported by blood vessels. - ANSWER-D.
Endocrine:
- Signals are released into the blood in order to impact tissues scattered throughout the body
Paracrine and Autocrine:
- Act locally
- Paracrine Messengers act on cells near the cell that secrete the messenger
- Autocrine Messengers act on the same cell that secretes the messenger
- Are not transported by blood vessels
[Flagged - Stuck between A and D, and went with A as I could reason out in my head made the most
sense]
Question 15 - Passage 3
An increase in which of the following physiological variables is most likely to cause an increase in the
amount of EPO released by the kidneys in a healthy human adult?
A. Amount of aerobic exercise the person performs
B. Total amount of circulating hemoglobin
C. Rate of erythrocyte maturation
D. Cardiac output (volume of blood pumped by the heart per minute) - ANSWER-A.
EPO is produced in response to low tissue levels of oxygen, and causes the formation of RBCs.
When the amount of aerobic exercises increases, the person demand for oxygen increases as their
oxygen levels decrease, causing an increase in the amount of EPO released by the kidneys
D: Cardiac output would not directly affect EPO levels but heart rate might
, [Incorrect - Stuck between B and C, and simply didn't catch the mistake in B and C seemed too good]
Question 16 - Passage 3
Interested in developing ways to treat human strokes, researchers are attempting to develop forms of
EPO that act on CNS neurons without affecting erythrocyte production in the bone marrow. One benefit
of such a form of EPO in stroke treatment would be to:
A. promote apoptosis of damaged CNS neurons without affecting blood oxygen levels.
B. limit neuronal cell death without causing an immediate decrease in the oxygen-carrying capacity of
the blood.
C. prevent apoptosis in the CNS without causing a harmful increase in blood viscosity.
D. promote healing in the CNS without increasing the risk of developing tumors. - ANSWER-C.
2x2 question:
- The first major part was tackling that benefit of EPO was that it prevents apoptosis
- The other was noticing that it mentioned angiogenesis which means that it increases the
oxygencarrying capacity of the blood due to supporting more forms of oxygenated blood transport
- Therefore only C would be left, which makes sense as no major increase in blood viscosity would be
ideal to treat a stroke victim.
[Flagged - Said cytosol and then released that it was a glycoprotein and not a steroid]
Question 19 - Passage 3
In which of the following cellular locations does EPO most likely initially bind EPOR in erythrocyte
precursor cells?
A. Cytosol
B. Endoplasmic reticulum
C. Nucleus
D. Plasma membrane - ANSWER-D.
