QUESTIONS WITH COMPLETE
SOLUTIONS
, What is the action of diuretics? - ANSWERS1. They promote diuresis, the increased
production of urine
2. Works by altering the excretion or reabsorption of electrolytes
Loop diuretics - ANSWERS1. Bind reversibly to this carrier protein, thus reducing or
abolishing NaCl reabsorption
2. Furosemide, and Bumetanide
Thiazide diuretics - ANSWERS1. Causes the kidneys to make more urine, which allows
the body to get rid of extra sodium
2. Hydrochlorothiazide
Potassium sparing diuretics - ANSWERS1. Increase diuresis (urination) without the loss
of potassium
2. Spironolatone, Triamterene
Osmotic diuretics - ANSWERS1. Increased urination due to the presence of certain
substances in the fluid filtered by the kidneys
2. Mannitol
What are Statins? - ANSWERSAntihyperlipidemic medications
What do Statins do? - ANSWERS1. Aid in lowering LDL levels and increasing HDL
levels
2. Reducing the amount of cholesterol made by the liver and helping the liver remove
cholesterol that is already in the blood
What is the most serious adverse effect of Statins? - ANSWERSRhabdomyolysis
What is Rhabdomyolysis? - ANSWERSThe breakdown of muscle tissue releases
muscle fiber contents into the blood. these substances can cause kidney damage
What are side effect of Rhabdomyolysis? - ANSWERS1. Fatigue
2. Red urine
3. Water-electrolyte imbalance
4. Muscle weakness
5. Muscle stiffness
6. Muscle pain
Normal LDL cholesterol lab value - ANSWERSBelow 100 mg/dL
Normal HDL cholesterol lab value - ANSWERSAbove 50 mg/dL