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They combat the extrapyramidal side effects of the neuroleptic drug. - (ANSWER)A nurse is
administering medications to clients on a psychiatric unit. What does the nurse identify as the reason
that so many psychiatric clients are given the drug benztropine or trihexyphenidyl in conjunction with
the phenothiazine-derivative neuroleptic medications?
Torticollis - (ANSWER)acute dystonia that involves muscle spasms of the neck; develops within 1 to 5
days after beginning therapy with a conventional antipsychotic
Tardive dyskinesia - (ANSWER)involuntary repetitious tonic muscular spasms that involve the face,
tongue, lips, limbs, and trunk; takes several months to years to develop after the start of therapy with a
conventional antipsychotic
d/c if observed, may be reversible
Pseudoparkinsonism - (ANSWER)extrapyramidal tract response that includes masklike facies, shuffling
gait, pill-rolling tremors, stooped posture, and drooling; develops within several days to 1 month after
the start of therapy with a conventional antipsychotic
Neuroleptic malignant syndrome - (ANSWER)severe, potentially fatal response to conventional
antipsychotics
caused by acute reduction in dopamine activity, precipitating hyperthermia/pyrexia, tachycardia,
tachypnea, unstable blood pressure, dyskinesia, incontinence, decreased level of consciousness
Clozapine - (ANSWER)2nd gen atypical antipsychotic drug that is more effective than other second-
generation antipsychotics
Seizures, sedation, and akathisia are common side effects
contraindicated in clients with bone marrow depression
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may cause agranulocytosis, the client's white blood cell (WBC) count should be monitored weekly. The
drug should be discontinued if the count falls below 3,000/mm 3
use with caution in clients with seizures
Isocarboxazid - (ANSWER)MAOI
Circulatory collapse is associated with toxicity
fluphenazine - (ANSWER)typical antipsychotic
Acute dystonic reactions such as tremors, dyskinesia, and akathisia are observable side effects
decreased salivating
haloperidol - (ANSWER)antipsychotic drug used in the long-term treatment of psychosis
Gynecomastia is one of the adverse effects of this drug
Potential adverse effects: pseudoparkinsonism and urinary retention related to extrapyramidal
syndrome
Ziprasidone - (ANSWER)atypical antipsychotic
contraindicated in clients with a history of dysrhythmias