Week 6 Knowledge Check Quiz Advanced Patho NSG
5003 REVIEW QUESTIONS AND ANSWERS 2025/2026
Which organ is stimulated during the alarm phase of the general adaption syndrome
(GAS) - 100 correct answer as-Hypothalamus
During an anticipatory response to stress, the reaction from the limbic system is
stimulated by the - 100 correct answer as-Paraventricular nucleus of the hypothalamus
Which hormone prompts increased anxiety, vigilance, and arousal during a stress
response - 100 correct answer as-Norepinephrine
Perceived stress elicits and emotional, anticipatory response that begins where - 100
correct answer as-Limbic system
During a stress response, the helper T (Th)1 response is suppress by which hormone -
100 correct answer as-Cortisol
What is the effect that low-serum albumin has on the central stress response - 100
correct answer as-Impaired circulation of epinephrine and norepinephrine
Stress-age syndrome directly results in depressed function of which system - 100
correct answer as-Immune
Stress-induced sympathetic stimulation of the adrenal medulla causes the secretion of -
100 correct answer as-Epinephrine and norepinephrine
Stress-induced norepinephrine results in - 100 correct answer as-Peripheral
vasoconstriction
Released stress-induced cortisol results in the stimulation of gluconeogenesis by
affecting which structure - 100 correct answer as-Adrenal cortex
What is the effect of increased secretions of epinephrine, glucagon, and growth
hormone - 100 correct answer as-Hyperglycemia
Which hormone increases the formation of glucose from amino acids and free fatty
acids - 100 correct answer as-Cortisol
What effect do androgens have on lymphocytes - 100 correct answer as-Suppression of
B and T cell responses
Which gland regulates the immune response and mediates the apparent effects of
circadian rhythms on immunity - 100 correct answer as-Pineal
,Which cytokines initiate the production of corticotropin-releasing hormone (CRH) - 100
correct answer as-IL-1 and IL-6
The release of which cytokines is triggered by bacterial or viral infections, cancer, and
tissue injury that, in turn, initiate a stress response - 100 correct answer as-IFN, TNF-B
and IL-6
The action of which hormone helps explain increases in affective anxiety and eating
disorders, mood cycles, and vulnerability to autoimmune and inflammatory diseases in
women as a result of stimulation of the CRH gene promote and central norepinephrine
system - 100 correct answer as-Estrogen
What effect does estrogen have on lymphocytes - 100 correct answer as-Depression of
T-cell functions and enhancement of B-cell function
Which statement is true concerning the difference between stress-induced hormonal
alterations of men and women - 100 correct answer as-Androgens appear to induce a
greater degree of immune cell apoptosis after injury, creating greater
immunosuppression in injured men than in injured women
Diagnostic blood work on individual who perceive themselves to be in a chromic stress
state will likely demonstrate - 100 correct answer as-Decreased Tc cells
What are the signs that a patient is in the adaptive stage of the general adaptation
syndrome - 100 correct answer as-The patient perceives his or her only options are to
run away or fight back
The most influential factor in whether a person will experience a stress reaction is his or
her - 100 correct answer as-Ability to cope
A reduction is an individual's number of natural killer (NK) cells appears to correlate with
an increased risk for the development of - 100 correct answer as-Depression
A nurse is providing care to a terminally ill adult who has been with his life partner for
over 56 years. Research supports the nurse's assessment of the life partner for signs of
- 100 correct answer as-Severe stress reaction
The action of which hormone helps explain increases in affective anxiety and eating
disorders, mood cycles, and vulnerability to autoimmune and inflammatory diseases in
women as a result of stimulation of the CRH gene promote and central norepinephrine
system - 100 correct answer as-Estrogen
Hypersensitivity is best defined as a(an):
A) Disturbance in the immunologic tolerance of self-antigens
B) Immunologic reaction of one person to the tissue of another person
,C) Altered immunologic response to an antigen that results in disease
D) Undetectable immune response in the presence of antigens - 100 correct answer as-
C) Altered immunologic response to an antigen that results in disease
A hypersensitivity reaction that produces an allergic response is called:
A) Hemolytic shock
B) Anaphylaxis
C) Necrotizing vasculitis
D) Systemic erythematosus - 100 correct answer as-B) Anaphylaxis
The common hay fever allergy is expressed through a reaction that is mediated by
which class of immunoglobulins?
A) IgE
B) IgG
C) IgM
D) T cells - 100 correct answer as-A) IgE
Which type of antibody is involved in type I hypersensitivity reaction?
A) IgA
B) IgE
C) IgG
D) IgM - 100 correct answer as-B) IgE
Blood transfusion reactions are an example of:
A) Autoimmunity
B) Alloimmunity
C) Homoimmunity
D) Hypersensitivity - 100 correct answer as-B) Alloimmunity
During an IgE-mediated hypersensitivity reaction, which leukocyte is activated?
A) Neutrophils
B) Monocytes
C) Eosinophils
D) T lymphocytes - 100 correct answer as-C) Eosinophils
During an IgE-mediated hypersensitivity reaction, what causes bronchospasm?
A) Bronchial edema caused by the chemotactic factor of anaphylaxis
B) Bronchial edema caused by binding of the cytotropic antibody
C) Smooth muscle contraction caused by histamine bound to H1 receptors
, D) Smooth muscle contraction caused by histamine bound to H2 receptors - 100 correct
answer as-C) Smooth muscle contraction caused by histamine bound to H1 receptors
During an IgE-mediated hypersensitivity reaction, the degranulation of mast cells is a
result of which receptor action?
A) Histamine bound to H2
B) Chemotactic factor binding to the receptor
C) Epinephrine bound to mast cells
D) Acetylcholine bound to mast cells - 100 correct answer as-A) Histamine bound to H2
What characteristic do atopic individuals have that make them genetically predisposed
to develop allergies?
A) Greater quantities of histamine
B) More histamine receptors
C) Greater quantities of IgE
D) A deficiency in epinephrine - 100 correct answer as-C) Greater quantities of IgE
What is the mechanism that results in type II hypersensitivity reactions?
A) Antibodies coat mast cells by binding to receptors that signal its degranulation,
followed by a discharge of preformed mediators.
B) Antibodies bind to soluble antigens that were released into body fluids, and the
immune complexes are then deposited in the tissues.
C) Cytotoxic T lymphocytes or lymphokine-producing helper T 1 cells directly attack and
destroy cellular targets.
D) Antibodies bind to the antigens on the cell surface. - 100 correct answer as-D)
Antibodies bind to the antigens on the cell surface.
When mismatched blood is administered causing an ABO incompatibility, the
erythrocytes are destroyed by:
A) Complement-mediated cell lysis
B) Phagocytosis by macrophages
C) Phagocytosis in the spleen
D) Natural killer cells - 100 correct answer as-A) Complement-mediated cell lysis
When antibodies are formed against red blood cell antigens of the Rh system, the blood
cells are destroyed by:
A) Complement-mediated cell lysis
B) Phagocytosis by macrophages
C) Phagocytosis in the spleen
D) Neutrophil granules and toxic oxygen products - 100 correct answer as-C)
Phagocytosis in the spleen
5003 REVIEW QUESTIONS AND ANSWERS 2025/2026
Which organ is stimulated during the alarm phase of the general adaption syndrome
(GAS) - 100 correct answer as-Hypothalamus
During an anticipatory response to stress, the reaction from the limbic system is
stimulated by the - 100 correct answer as-Paraventricular nucleus of the hypothalamus
Which hormone prompts increased anxiety, vigilance, and arousal during a stress
response - 100 correct answer as-Norepinephrine
Perceived stress elicits and emotional, anticipatory response that begins where - 100
correct answer as-Limbic system
During a stress response, the helper T (Th)1 response is suppress by which hormone -
100 correct answer as-Cortisol
What is the effect that low-serum albumin has on the central stress response - 100
correct answer as-Impaired circulation of epinephrine and norepinephrine
Stress-age syndrome directly results in depressed function of which system - 100
correct answer as-Immune
Stress-induced sympathetic stimulation of the adrenal medulla causes the secretion of -
100 correct answer as-Epinephrine and norepinephrine
Stress-induced norepinephrine results in - 100 correct answer as-Peripheral
vasoconstriction
Released stress-induced cortisol results in the stimulation of gluconeogenesis by
affecting which structure - 100 correct answer as-Adrenal cortex
What is the effect of increased secretions of epinephrine, glucagon, and growth
hormone - 100 correct answer as-Hyperglycemia
Which hormone increases the formation of glucose from amino acids and free fatty
acids - 100 correct answer as-Cortisol
What effect do androgens have on lymphocytes - 100 correct answer as-Suppression of
B and T cell responses
Which gland regulates the immune response and mediates the apparent effects of
circadian rhythms on immunity - 100 correct answer as-Pineal
,Which cytokines initiate the production of corticotropin-releasing hormone (CRH) - 100
correct answer as-IL-1 and IL-6
The release of which cytokines is triggered by bacterial or viral infections, cancer, and
tissue injury that, in turn, initiate a stress response - 100 correct answer as-IFN, TNF-B
and IL-6
The action of which hormone helps explain increases in affective anxiety and eating
disorders, mood cycles, and vulnerability to autoimmune and inflammatory diseases in
women as a result of stimulation of the CRH gene promote and central norepinephrine
system - 100 correct answer as-Estrogen
What effect does estrogen have on lymphocytes - 100 correct answer as-Depression of
T-cell functions and enhancement of B-cell function
Which statement is true concerning the difference between stress-induced hormonal
alterations of men and women - 100 correct answer as-Androgens appear to induce a
greater degree of immune cell apoptosis after injury, creating greater
immunosuppression in injured men than in injured women
Diagnostic blood work on individual who perceive themselves to be in a chromic stress
state will likely demonstrate - 100 correct answer as-Decreased Tc cells
What are the signs that a patient is in the adaptive stage of the general adaptation
syndrome - 100 correct answer as-The patient perceives his or her only options are to
run away or fight back
The most influential factor in whether a person will experience a stress reaction is his or
her - 100 correct answer as-Ability to cope
A reduction is an individual's number of natural killer (NK) cells appears to correlate with
an increased risk for the development of - 100 correct answer as-Depression
A nurse is providing care to a terminally ill adult who has been with his life partner for
over 56 years. Research supports the nurse's assessment of the life partner for signs of
- 100 correct answer as-Severe stress reaction
The action of which hormone helps explain increases in affective anxiety and eating
disorders, mood cycles, and vulnerability to autoimmune and inflammatory diseases in
women as a result of stimulation of the CRH gene promote and central norepinephrine
system - 100 correct answer as-Estrogen
Hypersensitivity is best defined as a(an):
A) Disturbance in the immunologic tolerance of self-antigens
B) Immunologic reaction of one person to the tissue of another person
,C) Altered immunologic response to an antigen that results in disease
D) Undetectable immune response in the presence of antigens - 100 correct answer as-
C) Altered immunologic response to an antigen that results in disease
A hypersensitivity reaction that produces an allergic response is called:
A) Hemolytic shock
B) Anaphylaxis
C) Necrotizing vasculitis
D) Systemic erythematosus - 100 correct answer as-B) Anaphylaxis
The common hay fever allergy is expressed through a reaction that is mediated by
which class of immunoglobulins?
A) IgE
B) IgG
C) IgM
D) T cells - 100 correct answer as-A) IgE
Which type of antibody is involved in type I hypersensitivity reaction?
A) IgA
B) IgE
C) IgG
D) IgM - 100 correct answer as-B) IgE
Blood transfusion reactions are an example of:
A) Autoimmunity
B) Alloimmunity
C) Homoimmunity
D) Hypersensitivity - 100 correct answer as-B) Alloimmunity
During an IgE-mediated hypersensitivity reaction, which leukocyte is activated?
A) Neutrophils
B) Monocytes
C) Eosinophils
D) T lymphocytes - 100 correct answer as-C) Eosinophils
During an IgE-mediated hypersensitivity reaction, what causes bronchospasm?
A) Bronchial edema caused by the chemotactic factor of anaphylaxis
B) Bronchial edema caused by binding of the cytotropic antibody
C) Smooth muscle contraction caused by histamine bound to H1 receptors
, D) Smooth muscle contraction caused by histamine bound to H2 receptors - 100 correct
answer as-C) Smooth muscle contraction caused by histamine bound to H1 receptors
During an IgE-mediated hypersensitivity reaction, the degranulation of mast cells is a
result of which receptor action?
A) Histamine bound to H2
B) Chemotactic factor binding to the receptor
C) Epinephrine bound to mast cells
D) Acetylcholine bound to mast cells - 100 correct answer as-A) Histamine bound to H2
What characteristic do atopic individuals have that make them genetically predisposed
to develop allergies?
A) Greater quantities of histamine
B) More histamine receptors
C) Greater quantities of IgE
D) A deficiency in epinephrine - 100 correct answer as-C) Greater quantities of IgE
What is the mechanism that results in type II hypersensitivity reactions?
A) Antibodies coat mast cells by binding to receptors that signal its degranulation,
followed by a discharge of preformed mediators.
B) Antibodies bind to soluble antigens that were released into body fluids, and the
immune complexes are then deposited in the tissues.
C) Cytotoxic T lymphocytes or lymphokine-producing helper T 1 cells directly attack and
destroy cellular targets.
D) Antibodies bind to the antigens on the cell surface. - 100 correct answer as-D)
Antibodies bind to the antigens on the cell surface.
When mismatched blood is administered causing an ABO incompatibility, the
erythrocytes are destroyed by:
A) Complement-mediated cell lysis
B) Phagocytosis by macrophages
C) Phagocytosis in the spleen
D) Natural killer cells - 100 correct answer as-A) Complement-mediated cell lysis
When antibodies are formed against red blood cell antigens of the Rh system, the blood
cells are destroyed by:
A) Complement-mediated cell lysis
B) Phagocytosis by macrophages
C) Phagocytosis in the spleen
D) Neutrophil granules and toxic oxygen products - 100 correct answer as-C)
Phagocytosis in the spleen
