TEST BANK
Modern Blood Banking & Transfusion
Practices Seventh Edition
by Denise M. Harmening PhD MLS(ASCP) (Author)
,TABLS OF CONTENTS
Part I Fundamental Concepts
1 Red Blood Cell and Platelet Preservation: Historical Perspectives and Current Trends
2 Basic Genetics
3 Fundamentals of Immunology
4 Concepts in Molecular Biology
Part II Blood Groups and Serological Testing
5 The Antiglobulin Test
6 The ABO Blood Group System
7 The Rh Blood Group System
8 Blood Group Terminology & Common Blood Groups: The Lewis System, P, I, MNS, Kell, Duffy,
Kidd, Lutheran
9 Uncommon Blood Groups
10 Detection and Identification of Antibodies
11 Pre-transfusion Testing
12 Blood Bank Testing Technologies and Automation
Part III Transfusion Practices
13 Donor Selection
14 Transfusion-Transmitted Diseases
15 Component Preparation
16 Transfusion Therapy
17 Adverse Effects of Blood Transfusion
18 Apheresis
19 Cellular Therapy in the Transplant Setting
20 Hemolytic Disease of the Fetus and Newborn
21 Autoimmune Hemolytic Anemias
22 Tissue Banking
Part IV Leukocyte Antigens and Relationship Testing
23 The HLA System
24 Relationship Testing
Part V Quality Management and Compliance
25 Quality Management in the Blood Bank
26 Patient Blood Management
27 Transfusion Safety and Federal Regulatory Requirements
28 Laboratory Information Systems in the Blood Bank
29 Medicolegal and Ethical Aspects of Providing Blood Collection and Transfusion Services
,Chapter 1
Rbcs And Platelet Preservation: Historical Perspectives And Current Trends
MULTIPLE CHOICE
Identify The Choice That Best Completes The Statement Or Answers The Question.
1. Which Metabolic Pathway Is Responsible For Generating 90% Of The ATP For The RBC?
A. Pentose Phosphate Shunt C. Glycolysis
B. Luebering-Rapoport Shunt D. Methemoglobin Reductase
2. A Unit Of Blood Was Returned To The Blood Bank Before It Was Spiked. Apparently The
Patient’s IV Failed. The Unit Of Blood Was Outside The Blood Bank For 35 Minutes. Which Of The
Statements Below Is Most Accurate?
A. The Unit Of Blood Should Be Discarded Immediately.
B. The Unit Of Blood Can Be Returned To Inventory.
C. The Unit Of Blood Must Be Transfused Within 4 Hours Or Be Discarded At The End Of That Time.
D. The Unit Of Blood Must Be Transfused With 24 Hours.
3. What Is The Average Diameter Of A Platelet?
A. 5 To 10 µm C. 1 To 2 µm
B. 2 To 4 µm D. 4 To 6 µm
4. In The Normal Hemoglobin-Oxygen Dissociation Curve, What Percentage Of Oxygen Is Released
To The Tissues When PO2 Averages 40 Mm Hg?
A. 75% C. 100%
B. 25% D. 50%
5. What Factors Are Known To Influence Platelet Metabolism And Function?
A. Storage Temperature C. Platelet Count
B. Initial Ph D. All Of The Above
6. Which Of The Following Red Blood Cell Morphologies May Be Present On The Peripheral Blood
Smear As A Result Of Loss Of RBC Membrane?
A. Spherocytes C. Burr Cells
, B. Target Cells D. Schistocytes
7. What Does The Term Autologous Transfusion Refer To?
A. A Parent Donating Blood For His Or Her Child
B. An Individual Donating Blood For A Friend
C. An Individual Donating Blood For A Relative
D. An Individual Donating Blood For His Or Her Own Transfusion
8. What Is The Primary Function Of Hemoglobin?
A. Iron Metabolism C. Oxygen Transport
B. Porphyrin Synthesis D. Signal Transduction
9. All Of The Following Areas Of Red Blood Cell Biology Are Crucial For Normal Erythrocyte Survival
Except:
A. Cellular Metabolism. C. Site Of The ABO Antigen Attachment.
B. RBC Membrane. D. Hemoglobin Structure.
10. What Is The Correct Biochemical Composition Of The RBC Membrane?
A. 52% Protein, 40% Lipid, 8% Carbohydrate
B. 40% Protein, 8% Lipid, 52% Carbohydrate
C. 8% Protein, 52% Lipid, 40% Carbohydrate
D. 8% Lipid, 40% Carbohydrate, 52% Protein
11. All Of The Following Biochemical Changes Are Associated With Loss Of Red Blood Cell
Viability Upon Storage
Except:
A. Decreased Ph. C. Increased ATP Level.
Modern Blood Banking & Transfusion
Practices Seventh Edition
by Denise M. Harmening PhD MLS(ASCP) (Author)
,TABLS OF CONTENTS
Part I Fundamental Concepts
1 Red Blood Cell and Platelet Preservation: Historical Perspectives and Current Trends
2 Basic Genetics
3 Fundamentals of Immunology
4 Concepts in Molecular Biology
Part II Blood Groups and Serological Testing
5 The Antiglobulin Test
6 The ABO Blood Group System
7 The Rh Blood Group System
8 Blood Group Terminology & Common Blood Groups: The Lewis System, P, I, MNS, Kell, Duffy,
Kidd, Lutheran
9 Uncommon Blood Groups
10 Detection and Identification of Antibodies
11 Pre-transfusion Testing
12 Blood Bank Testing Technologies and Automation
Part III Transfusion Practices
13 Donor Selection
14 Transfusion-Transmitted Diseases
15 Component Preparation
16 Transfusion Therapy
17 Adverse Effects of Blood Transfusion
18 Apheresis
19 Cellular Therapy in the Transplant Setting
20 Hemolytic Disease of the Fetus and Newborn
21 Autoimmune Hemolytic Anemias
22 Tissue Banking
Part IV Leukocyte Antigens and Relationship Testing
23 The HLA System
24 Relationship Testing
Part V Quality Management and Compliance
25 Quality Management in the Blood Bank
26 Patient Blood Management
27 Transfusion Safety and Federal Regulatory Requirements
28 Laboratory Information Systems in the Blood Bank
29 Medicolegal and Ethical Aspects of Providing Blood Collection and Transfusion Services
,Chapter 1
Rbcs And Platelet Preservation: Historical Perspectives And Current Trends
MULTIPLE CHOICE
Identify The Choice That Best Completes The Statement Or Answers The Question.
1. Which Metabolic Pathway Is Responsible For Generating 90% Of The ATP For The RBC?
A. Pentose Phosphate Shunt C. Glycolysis
B. Luebering-Rapoport Shunt D. Methemoglobin Reductase
2. A Unit Of Blood Was Returned To The Blood Bank Before It Was Spiked. Apparently The
Patient’s IV Failed. The Unit Of Blood Was Outside The Blood Bank For 35 Minutes. Which Of The
Statements Below Is Most Accurate?
A. The Unit Of Blood Should Be Discarded Immediately.
B. The Unit Of Blood Can Be Returned To Inventory.
C. The Unit Of Blood Must Be Transfused Within 4 Hours Or Be Discarded At The End Of That Time.
D. The Unit Of Blood Must Be Transfused With 24 Hours.
3. What Is The Average Diameter Of A Platelet?
A. 5 To 10 µm C. 1 To 2 µm
B. 2 To 4 µm D. 4 To 6 µm
4. In The Normal Hemoglobin-Oxygen Dissociation Curve, What Percentage Of Oxygen Is Released
To The Tissues When PO2 Averages 40 Mm Hg?
A. 75% C. 100%
B. 25% D. 50%
5. What Factors Are Known To Influence Platelet Metabolism And Function?
A. Storage Temperature C. Platelet Count
B. Initial Ph D. All Of The Above
6. Which Of The Following Red Blood Cell Morphologies May Be Present On The Peripheral Blood
Smear As A Result Of Loss Of RBC Membrane?
A. Spherocytes C. Burr Cells
, B. Target Cells D. Schistocytes
7. What Does The Term Autologous Transfusion Refer To?
A. A Parent Donating Blood For His Or Her Child
B. An Individual Donating Blood For A Friend
C. An Individual Donating Blood For A Relative
D. An Individual Donating Blood For His Or Her Own Transfusion
8. What Is The Primary Function Of Hemoglobin?
A. Iron Metabolism C. Oxygen Transport
B. Porphyrin Synthesis D. Signal Transduction
9. All Of The Following Areas Of Red Blood Cell Biology Are Crucial For Normal Erythrocyte Survival
Except:
A. Cellular Metabolism. C. Site Of The ABO Antigen Attachment.
B. RBC Membrane. D. Hemoglobin Structure.
10. What Is The Correct Biochemical Composition Of The RBC Membrane?
A. 52% Protein, 40% Lipid, 8% Carbohydrate
B. 40% Protein, 8% Lipid, 52% Carbohydrate
C. 8% Protein, 52% Lipid, 40% Carbohydrate
D. 8% Lipid, 40% Carbohydrate, 52% Protein
11. All Of The Following Biochemical Changes Are Associated With Loss Of Red Blood Cell
Viability Upon Storage
Except:
A. Decreased Ph. C. Increased ATP Level.
