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NR565 / NR 565 Final Exam (Latest 2023/2024 Update):Advanced Pharmacology Fundamentals

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NR565 / NR 565 Final Exam (Latest 2023/2024 Update):Advanced Pharmacology Fundamentals

Institution
NR565 / NR 565
Course
NR565 / NR 565

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Final Exam: NR565/ NR 565 s s s s s s s s




(Latest 2023/ 2024 Update)
s s s s s s




Advanced Pharmacology ss




Exam Review| Questions ss




and Verified
Answers -Chamberlain s s ss




1. A patient has a TSH of .28, a free T4 of 3, and a
free T3 over 650. What medication should she be started
ss



on?
ss




 Answer: Methimazole, PTU, radioactive iodine. These
labs indicate hyperthyroidism. Treatment for thyroid
ss



storm: K iodide or strong iodine solution to
ss



suppress thyroid release. Methimazole to suppress
ss



thyroid synthesis.
ss




2. When is it appropriate to increase insulin needs?


 Answer: Pregnancy (after first trimester), stress,
infection,
ss weight loss, adolescent growth spurt.
s



DECREASE for exercise and first trimester.
ss




3. What is the TDD of a person that weighs 70kg?

IF a person is eating a 50 carb meal, how much insulin will
ss be needed based on the TDD from the above question?


 Answer: 42 TDD : 21 basal 21 bolus (Wt in kg
x 0.6; 50% long acting and 50% rapid acting)
ss




 500 divided by (the TDD) 42 = 12. (carb to
s



insulin ratio) then (meal carbs) 50 divided
ss 12=
4.1 units with short acting insulin

,4. s s s s "As long as the short-acting insulin is drawn up first I can
mix my insulin glargine with it."


 Answer: Of the long-acting medications, ONLY NPH
the intermediate duration is suitable for mixing with
s s



the short action insulins.
ss s




5. A women who is taking Pioglitazone states, "I'm glad that
this medication promotes
ss weight loss."


 Answer: First this medication promotes increase in
s



LDL levels, which increases cardiovascular risk.
ss



Also, she's a female so speak about exercise and
weight bearing exercise d/t possible increased risk
ss s



for fractures.
s s




6. s s MOA
s s Glucocorticoid

Answer: Most effective in long-term control of airway
inflammation



7. s s s s Cromolyn MOA


 Answer: Used as prophylaxis for mild to moderate
asthma



8. s s Antibodies MOA
Monoclonal
s s




 Answer: Used for allergy-related asthma and
Eosinophilic asthma. Omalizumab for allergy related
and Ben ralizumab, mepliz, and resliz are
ss for
eosinophilic
ss




9. Leukotriene MOA

,  Answer: Second-line therapy to reduce
inflammation and bronchoconstriction
ss




10. B2 adrenergic agonists MOA


 Answer: Can be used PRN, for EIB, COPD
exacerbations, and maintenance therapy
ss




11. methylxanthines MOA


 Answer: Maintenance therapy for chronic stable asthma
(theophylline).
ss



P. 570. Use ONLY if B2 or anticholinergics are not
appropriate.
ss




12. anticholinergic MOA


 Answer: Approved for bronchospasm related to COPD



13. •What are some risk factors of fatal asthma attacks?


 Answer: Uncontrolled, hospitalized recently, triggers,



14. •Roflumilast (select all that apply)
1. Reduces inflammation
2. Not intended during pregnancy
3. Approved for asthma
4. First-line drug for COPD


 Answer: Reduces inflammation, not intended for
pregnancy, approved only for COPD, Second-line
ss



drug for COPD
ss

,  Uses for exacerbations prophylaxis in pts with
severe COPD with a primary chronic bronchitis
ss



component.
ss




15. What pt education can you provide a patient for ICS use?


 Answer: Rinse d/t oropharyngeal candidiasis
and dysphonia (hoarseness, difficulty speaking).



16. What patient teaching can a provider give when prescribing a
PPI?
ss




 Answer: Hypomagnesia symptoms: muscle cramps, s



tremors, cramps, and palpitations. Check Mg levels
ss



periodically especially in the elderly. Get enough
ss



calcium and VIT D. call if having diarrhea
ss



(Cdiff)
ss




17. What patient teaching can a provider give when prescribing an
H2RA?
ss




 Answer: Report lethargy, solmnolance, restlessness,
confusion
ss or hallucinations. (CNS effects).
Teach about ss possible reduced libido, s



impotence, gynecomastia, pneumonia.
ss P.594 s



Cimetidine interacts
s



with CYP system so check with pt if they are
taking warfarin, phenytoin, theophylline, lidocaine.
ss




18. A patient presents with a complaint of reflux and constipation. s



ss He states that he drinks enough water, and admits he has
ss gained 30lbs. He also states that he has been having s



ss "reflux" type symptoms. What are your next stepss s s s s s s s s s s s s s s s



s s for education?
s s ss




 Answer: Educate that weight gain can promote
reflux symptoms, ask about any otc use such as
antacids which may cause constipation.

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Institution
NR565 / NR 565
Course
NR565 / NR 565

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Uploaded on
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Number of pages
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Written in
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Type
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