NAPLEX Antibiotics EXAM 2025/2026 Actual Complete Real
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what weight do you use to IBW (unless TBW is less)
dose aminoglycosides? *use ABW if obese ( > 30% IBW)
what organisms are gram (-): GNR, PA
aminoglycosides mainly
active against?
gent/tobra: 4-7 mg/kg
extended interval dosing of
amikacin: 15-20 mg/kg
the aminoglycosides?
*draw random level within 6-16 hours after dose
adjust body weight (ABW) IBW + [0.4(TBW - IBW)]
formula?
desired trough (traditional trough: < 2
dosing) for gent/tobra? mcg/mL
peak? peak: 5-10
mcg/mL
amoxicilin brand name Amoxil
what organisms do the mainly gram (+), some gram (-)
penicillins cover?
which penicillin is the DOC in amoxicillin
acute otitis media?
which penicillin has activity piperacillin
against PA?
nafcillin
which penicillins do not
oxacillin
require renal dosing?
dicloxacill
in
Does Amoxil suspension need no - stable for 14 days at room temperature
to be refrigerated?
1/22
,9/17/25, 9:45 AM NAPLEX antibiotics
how do you need to take Pen on an empty stomach
VK?
what IV fluid is ampicillin only NS
compatible with?
what are the main probenacid, allopurinol - increased
penicillin drug penicillin levels may decrease
interactions? levels of oral contraceptives
what type of killing do time-dependent
cephalosporins exhibit?
what are the first generation cefazolin and cephalexin
cephalosporins?
what organisms are every strep/staph and GNR
cephalosporin active
against?
which cephalosporins are cefepime and ceftazidime
active against PA?
cefazolin brand name? Kefzol
cephalexin brand name? Keflex
ceftriaxone brand name and Rocephin - 3rd gen
generation?
cefuroxime brand name? Ceftin, Zinacef
what is the lone 4th cefepime (Maxipime) - 1-2 g Q8-12
generation cephalosporin?
what generation is ceftaroline 5th
(Teflaro) in?
seizures with
what are the main side effects accumulation
of cephalosporins? increased LFTs
GI upset, diarrhea
bone marrow suppression
2/22
, 9/17/25, 9:45 AM NAPLEX antibiotics
which cephalosporins DO ceftriaxone (Rocephin) - 3rd generation
NOT require renal dose
adjustments?
probenacid, allopurinol - increased levels of cephalosporins
what are the main drug
interactions of
may decrease effectiveness of oral contraceptives
cephalosporins?
What type of killing do time-dependent bactericidal
carbapenems exhibit?
generic name for Primaxin? imipenem / cilastatin
everything
what organisms do the
*ertapenem = no EC or PA
carbapenems cover?
*no MRSA
Brand name for meropenem? Merrem
Brand name for ertapenem? Invanz
Brand name for Doripenem? Doribax
can carbapenems be used NO
in a PCN allergy?
uricosuric agents
carbapenem drug
interactions? (probenacid, allopurinol)
caution with seizures
MOA of flouroquinolones inhibit bacterial DNA topoisomerase IV and inhibit DNA gyrase
what type of killing to concentration-dependent bactericidal
flouroquinolones exhibit?
brand name of moxifloxacin? Avelox
what do flouroquinolones tendon inflammation and rupture
have a black box warning
for?
photosensitivi
side effects of ty arthropathy
flouroquinolones?
in children QT
prolongation
antacids, iron, calcium, zinc, mvi - separate by 2 hours
can increase levels of warfarin, sulfonylureas, and QT-
quinolone drug interactions?
prolonging drugs probenacid and NSAIDs can
increase FQ levels
3/22