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NU 578 Study Guide – Test 2 & Unit 2 Combined 2025/2026 | 150+ Solved Q&A on Migraine Treatment, Antipsychotics, Parkinson’s, Lithium, Antidepressants, Benzodiazepines & CNS Agents

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This comprehensive NU 578 Study Guide combines Test 2 and Unit 2 materials into one all-inclusive reference for the 2025/2026 academic year, featuring 150+ fully solved and annotated questions and answers. It is specifically curated for graduate-level nursing students in MSN, APRN, and DNP pharmacology courses, offering in-depth clinical and theoretical insights into neuropharmacology, psychiatric medications, and pain management. The content thoroughly explores critical drug classes, mechanisms of action, indications, side effects, contraindications, and clinical applications. Included topics: Migraine prophylaxis and treatment: beta-blockers, TCAs, antiepileptics, triptans, menstrual-related headaches First and second-generation antipsychotics: haloperidol, clozapine, risperidone, quetiapine, and extrapyramidal effects Benzodiazepine and opioid pharmacology: indications, adverse effects, sedation protocols, abuse potential, antidotes Parkinson’s Disease management: levodopa-carbidopa, dopamine agonists, MAO-B and COMT inhibitors, dyskinesias, early symptoms Mood stabilizers and psychiatric drugs: lithium monitoring, antidepressant MOAs (SSRIs, TCAs, MAOIs), anticholinergic toxicity CNS pharmacodynamics: neurotransmitters (GABA, dopamine, serotonin, acetylcholine), blood-brain barrier dynamics, tolerance, and dependence Illicit substances and abuse profiles: heroin, marijuana, LSD, cocaine, and their pharmacokinetic properties Deep brain stimulation and cell-based therapies in Parkinson’s Disease Each entry is clearly labeled and structured for rapid review, with pharmacologic rationale and clinical tips embedded throughout. This study guide is ideal for: MSN, APRN, and DNP students Nurse practitioners in training Pharmacology and pathophysiology educators Healthcare professionals preparing for advanced pharmacology exams or certification Whether used for exam prep, lecture reinforcement, or clinical rotation support, this document delivers concise, evidence-based coverage across essential neuro and psychopharmacologic domains. Keywords: NU 578 pharmacology, migraine treatment guide, beta blockers for headache, triptans contraindications, antipsychotic drugs, extrapyramidal side effects, Parkinson’s medications, levodopa-carbidopa, lithium toxicity, SSRIs vs TCAs, MAOI interactions, benzodiazepine antidotes, opioid abuse in healthcare, CNS neurotransmitters, deep brain stimulation, blood-brain barrier drugs, neuroleptic malignant syndrome, antidepressant side effects, DNP pharmacology, APRN exam prep

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NU 578 Study Guide Test 2 AND UNIT 2
COMBINED 2025/2026 Exam Questions
and Answers | 100% Solved



preferred drugs for migraine headache prophylaxis - 🧠 ANSWER

✔✔propranolol, divalproex, amitriptyline


appropriate drugs for migraine headache prophylaxis - 🧠 ANSWER

✔✔beta-adrenergic blocking agents - (propranolol [inderol], timolol

[blocadren]), antiepileptic drugs - (divalproex [depakote er], topiramate

[topomax], TCA's - amitriptyline [elavil], Estrogens for menstrual migraines -

estrogen gel, estrogen patch [alora, climara, esclim, estraderm, vivelle]


1st line drugs for migraine prevention - 🧠 ANSWER ✔✔beta blockers,

propanolol is used most often

-benefits take a few weeks to develop

,-most common s/e fatigue, tiredness. other s/e asthma exacerbation,

depression promotion

-usual dose 80-240mg daily by long acting single dose or divided short

acting dose bid

other beta blockers that may be used for migraine prevention - 🧠 ANSWER

✔✔timolol, atenolol, metoprolol, nadolol


indications for calcium channel blocker - 🧠 ANSWER ✔✔hypertension,

angina pectoris, prevention & Tx of atrial tachycardias


indications for tricyclics (amitriptyline) - 🧠 ANSWER ✔✔prevent migraine

and tension headaches in some people. dose 25-150mg daily at hs.

benefits do not depend on elevation of mood since they work in people who

are not depressed.

-can cause hypotension and cholinergic effects [dry mouth, constipation,

urinary retention, blurred vision, tachycardia].

-excessive doses can cause dysrhythmias


indications for triptans - 🧠 ANSWER ✔✔Migraine and Cluster HA


actions/role of opioids - 🧠 ANSWER ✔✔

, medications for cluster headache - 🧠 ANSWER ✔✔


medications for menstrual headache - 🧠 ANSWER ✔✔


side effects, contraindications of beta blockers - 🧠 ANSWER ✔✔


side effects, contraindications of triptans - 🧠 ANSWER ✔✔


side effects, contraindications of clozapine - 🧠 ANSWER ✔✔


which drugs have constrictive effects - 🧠 ANSWER ✔✔


benzodiazepine side effects, contraindications, antidotes - 🧠 ANSWER ✔✔


what are the atvantages of newer seizure medications - 🧠 ANSWER ✔✔


how are they used? - 🧠 ANSWER ✔✔


good agent to use for concious sedation - 🧠 ANSWER ✔✔


good agent for insomnia & panic attacks (short term use, not good for

chronic anxiety) - 🧠 ANSWER ✔✔


haldol (haloperidol) actions, side effects, contraindications - 🧠 ANSWER

✔✔




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