TEST BANK
Lehne’s Pharmacotherapeutics for Advanced Practice Nurses
and Physician Assistants
Laura D. Rosenthal, and Jacqueline Rosenjack Burchum
2nd Edition
,Table of Contents
Unit 01 Introduction 1
Unit 02 Basic Principles of Pharmacology 6
Unit 03 Drug Therapy Across the Life Span 15
Unit 04 Peripheral Nervous System Drugs 22
Unit 05 Central Nervous System Drugs 31
Unit 06 Drugs for Pain 38
Unit 07 Psychotherapeutic Drugs 43
Unit 08 Substance Use Disorders 51
Unit 09 Drugs That Affect the Heart, Blood Vessels, Blood, and Blood Volume 59
Unit 10 Drugs for Endocrine Disorders 68
Unit 11 Women’s Health 73
Unit 12 Men’s Health 78
Unit 13 Antiinflammatory, Antiallergic, and Immunologic Drugs 83
Unit 14 Drugs for Bone and Joint Disorders 91
Unit 15 Respiratory Tract Drugs 97
Unit 16 Gastrointestinal Drugs 102
Unit 17 Nutrition and Complimentary Therapies 110
Unit 18 Therapy of Infectious and Parasitic Diseases 116
Unit 19 Cancer Therapy 140
Unit 20 Drugs for Eyes, Ears, and Skin 145
Unit 21 Drugs Therapy in Acute Care 152
, Test Bank - Lehne’s Pharmacotherapeutics for Advanced Practice Nurses & Physician Assistants, 2e (Rosenthal, 2021)
Unit 01: Introduction
Rosenthal: Lehne's Pharmacotherapeutics for Advanced Practice Nurses and Physician
Assistants, 2nd Edition
MULTIPLE CHOICE
1.
A patient requests a refill of oxycodone (OxyContin) over the phone. What is the prescriber’s best initial
action?
A. Fax the prescription to the pharmacy
B. Schedule an in-person appointment
C. Verify adherence with the patient
D. Review the patient’s pain scale
Answer: B
Rationale: Schedule II drugs (like oxycodone) cannot be refilled by phone or fax. A handwritten prescription
and patient evaluation are required. Verifying adherence and assessing pain occur at the appointment.
2.
A patient using a metered-dose albuterol inhaler reports jitteriness and poor relief. The provider’s priority is
to:
A. Decrease the dose
B. Ask for a demonstration of inhaler technique
C. Auscultate lung sounds and check vital signs
D. Assess tobacco smoke exposure
Answer: C
Rationale: Assessing lung sounds/vitals evaluates drug effectiveness and safety first. Technique review is
important but not the immediate priority when symptoms persist.
3.
A patient with bacterial vaginosis is prescribed metronidazole. Which patient history finding is most
concerning?
A. Daily alcohol intake
B. Previous yeast infection
C. Family history of cervical cancer
D. Unemployment
Answer: A
Rationale: Alcohol with metronidazole causes a disulfiram-like reaction (flushing, vomiting, hypotension).
1|Page
, Test Bank - Lehne’s Pharmacotherapeutics for Advanced Practice Nurses & Physician Assistants, 2e (Rosenthal, 2021)
Yeast infection and family history aren’t contraindications. Financial barriers affect access but not immediate
safety.
4.
Before discharging a newly diagnosed type 1 diabetic, the provider’s priority teaching is:
A. Demonstrating insulin preparation and injection
B. Discussing storage and syringe disposal
C. Explaining diet and exercise influence on insulin
D. Teaching long-term complications of poor control
Answer: A
Rationale: Immediate safety hinges on proper insulin administration skills. Lifestyle and complications are
important but secondary at discharge.
5.
Which factor contributes most to a patient’s subtherapeutic drug level?
A. Nonadherence
B. Chronic constipation
C. Increased tolerance
D. Protein-binding drug interaction
Answer: A
Rationale: The leading cause of low drug levels is poor adherence (e.g., missed doses, financial constraints).
Constipation slightly increases absorption, and tolerance usually requires dose adjustments, not low levels.
6.
A provider reviews an older adult’s medications. Which combination raises the most concern?
A. Acetaminophen + oxycodone
B. Amitriptyline + diphenhydramine
C. Fexofenadine + OTC laxative
D. Zolpidem + sertraline
Answer: B
Rationale: Both drugs have strong anticholinergic/CNS depressive effects, compounding fall and confusion
risks. The others are generally safer together.
7.
Which lab studies best guide medication dosing in a frail elderly patient with dehydration and anuria? (Select
all)
2|Page
Lehne’s Pharmacotherapeutics for Advanced Practice Nurses
and Physician Assistants
Laura D. Rosenthal, and Jacqueline Rosenjack Burchum
2nd Edition
,Table of Contents
Unit 01 Introduction 1
Unit 02 Basic Principles of Pharmacology 6
Unit 03 Drug Therapy Across the Life Span 15
Unit 04 Peripheral Nervous System Drugs 22
Unit 05 Central Nervous System Drugs 31
Unit 06 Drugs for Pain 38
Unit 07 Psychotherapeutic Drugs 43
Unit 08 Substance Use Disorders 51
Unit 09 Drugs That Affect the Heart, Blood Vessels, Blood, and Blood Volume 59
Unit 10 Drugs for Endocrine Disorders 68
Unit 11 Women’s Health 73
Unit 12 Men’s Health 78
Unit 13 Antiinflammatory, Antiallergic, and Immunologic Drugs 83
Unit 14 Drugs for Bone and Joint Disorders 91
Unit 15 Respiratory Tract Drugs 97
Unit 16 Gastrointestinal Drugs 102
Unit 17 Nutrition and Complimentary Therapies 110
Unit 18 Therapy of Infectious and Parasitic Diseases 116
Unit 19 Cancer Therapy 140
Unit 20 Drugs for Eyes, Ears, and Skin 145
Unit 21 Drugs Therapy in Acute Care 152
, Test Bank - Lehne’s Pharmacotherapeutics for Advanced Practice Nurses & Physician Assistants, 2e (Rosenthal, 2021)
Unit 01: Introduction
Rosenthal: Lehne's Pharmacotherapeutics for Advanced Practice Nurses and Physician
Assistants, 2nd Edition
MULTIPLE CHOICE
1.
A patient requests a refill of oxycodone (OxyContin) over the phone. What is the prescriber’s best initial
action?
A. Fax the prescription to the pharmacy
B. Schedule an in-person appointment
C. Verify adherence with the patient
D. Review the patient’s pain scale
Answer: B
Rationale: Schedule II drugs (like oxycodone) cannot be refilled by phone or fax. A handwritten prescription
and patient evaluation are required. Verifying adherence and assessing pain occur at the appointment.
2.
A patient using a metered-dose albuterol inhaler reports jitteriness and poor relief. The provider’s priority is
to:
A. Decrease the dose
B. Ask for a demonstration of inhaler technique
C. Auscultate lung sounds and check vital signs
D. Assess tobacco smoke exposure
Answer: C
Rationale: Assessing lung sounds/vitals evaluates drug effectiveness and safety first. Technique review is
important but not the immediate priority when symptoms persist.
3.
A patient with bacterial vaginosis is prescribed metronidazole. Which patient history finding is most
concerning?
A. Daily alcohol intake
B. Previous yeast infection
C. Family history of cervical cancer
D. Unemployment
Answer: A
Rationale: Alcohol with metronidazole causes a disulfiram-like reaction (flushing, vomiting, hypotension).
1|Page
, Test Bank - Lehne’s Pharmacotherapeutics for Advanced Practice Nurses & Physician Assistants, 2e (Rosenthal, 2021)
Yeast infection and family history aren’t contraindications. Financial barriers affect access but not immediate
safety.
4.
Before discharging a newly diagnosed type 1 diabetic, the provider’s priority teaching is:
A. Demonstrating insulin preparation and injection
B. Discussing storage and syringe disposal
C. Explaining diet and exercise influence on insulin
D. Teaching long-term complications of poor control
Answer: A
Rationale: Immediate safety hinges on proper insulin administration skills. Lifestyle and complications are
important but secondary at discharge.
5.
Which factor contributes most to a patient’s subtherapeutic drug level?
A. Nonadherence
B. Chronic constipation
C. Increased tolerance
D. Protein-binding drug interaction
Answer: A
Rationale: The leading cause of low drug levels is poor adherence (e.g., missed doses, financial constraints).
Constipation slightly increases absorption, and tolerance usually requires dose adjustments, not low levels.
6.
A provider reviews an older adult’s medications. Which combination raises the most concern?
A. Acetaminophen + oxycodone
B. Amitriptyline + diphenhydramine
C. Fexofenadine + OTC laxative
D. Zolpidem + sertraline
Answer: B
Rationale: Both drugs have strong anticholinergic/CNS depressive effects, compounding fall and confusion
risks. The others are generally safer together.
7.
Which lab studies best guide medication dosing in a frail elderly patient with dehydration and anuria? (Select
all)
2|Page
