McCance & Huether’s Pathophysiology: The Biologic Basis for Disease in
Adults and Children 9th Edition by Julia Rogers DNP APRN CNS FNP-BC FAANP
9th Edition
,table of contents
Unit i the cell ......................................................................................................................................5
Chapter 01: cellular biology .................................................................................................................... 5
Chapter 02: altered cellular and tissue biology: environmental agents ................................................ 24
Chapter 03: the cellular environment: fluids and electrolytes, acids and bases ................................... 42
Unit ii genes and gene-environment interaction ................................................................................. 61
Chapter 04: genes and genetic diseases ............................................................................................... 61
Chapter 05: genes, environment-lifestyle, and common diseases ........................................................ 77
Chapter 06: epigenetics and disease..................................................................................................... 89
Unit iii mechanisms of self-defense .................................................................................................. 96
Chapter 07: innate immunity: inflammation and wound healing ......................................................... 96
Chapter 08: adaptive immunity .......................................................................................................... 117
Chapter 09: alterations in immunity and inflammation ...................................................................... 134
Chapter 10: infection .......................................................................................................................... 152
Chapter 11: stress and disease ........................................................................................................... 165
Unit iv cellular proliferation: cancer................................................................................................ 176
Chapter 12: cancer biology ................................................................................................................. 176
Chapter 13: cancer epidemiology ....................................................................................................... 194
Chapter 14: cancer in children ............................................................................................................ 203
Unit v the neurologic system .......................................................................................................... 210
Chapter 15: structure and function of the neurologic system ............................................................ 210
Chapter 16: pain, temperature regulation, sleep, and sensory function ............................................ 226
Chapter 17: alterations in cognitive systems, cerebral hemodynamics, and motor function ............. 247
Chapter 18: disorders of the central and peripheral nervous systems and the neuromuscular junction
............................................................................................................................................................ 267
Chapter 19: neurobiology of schizophrenia, mood disorders, and anxiety disorders ......................... 282
Chapter 20: alterations of neurologic function in children ................................................................. 291
Unit vi the endocrine system .......................................................................................................... 301
Chapter 21: mechanisms of hormonal regulation............................................................................... 301
Chapter 22: alterations of hormonal regulation ................................................................................. 314
Chapter 23: obesity and disorders of nutrition ................................................................................... 332
Unit vii the reproductive systems ................................................................................................... 339
Chapter 24: structure and function of the reproductive systems ....................................................... 339
, Chapter 25: alterations of the female reproductive system ............................................................... 353
Chapter 26: alterations of the male reproductive system .................................................................. 367
Chapter 27: sexually transmitted infections ....................................................................................... 375
Unit viii the hematologic system..................................................................................................... 387
Chapter 28: structure and function of the hematologic ..................................................................... 387
Chapter 29: alterations of erythrocytes, platelets, and hemostatic function ..................................... 401
Chapter 30: alterations of leukocyte and lymphoid function .............................................................. 416
Unit ix the cardiovascular and lymphatic systems ........................................................................... 425
Chapter 31: alterations of hematologic function in children .............................................................. 425
Chapter 32: structure and function of the cardiovascular and lymphatic systems ............................. 440
Chapter 33: alterations of cardiovascular function ............................................................................. 457
Unit x the pulmonary system.......................................................................................................... 477
Chapter 34: alterations of cardiovascular function in children ........................................................... 478
Chapter 35: structure and function of the pulmonary system ............................................................ 489
Chapter 36: alterations of pulmonary function................................................................................... 503
Unit xi the renal and urologic systems ............................................................................................ 526
Chapter 37: alterations of pulmonary function in children ................................................................. 526
Chapter 38: structure and function of the renal and urologic systems ............................................... 538
Chapter 39: alterations of renal and urinary tract function ................................................................ 552
Unit xii the digestive system ........................................................................................................... 567
Chapter 40: alterations of renal and urinary tract function in children .............................................. 567
Chapter 41: structure and function of the digestive system ............................................................... 578
Chapter 42: alterations of digestive function ...................................................................................... 594
Unit xiii the musculoskeletal system ............................................................................................... 609
Chapter 43: alterations of digestive function in children .................................................................... 610
Chapter 44: structure and function of the musculoskeletal system ................................................... 623
Chapter 45: alterations of musculoskeletal function .......................................................................... 640
Unit xiv the integumentary system ................................................................................................. 658
Chapter 46: alterations of musculoskeletal function in children ........................................................ 658
Chapter 47: structure, function, and disorders of the integument ..................................................... 671
Unit xv multiple interacting systems ............................................................................................... 688
Chapter 48: alterations of the integument in children........................................................................ 688
Chapter 49: shock, multiple organ dysfunction syndrome, and burns in adults ................................. 700
, Chapter 50: shock, multiple organ dysfunction syndrome, and burns in children .............................. 710