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NAGELHOUT-PHARM 2-Exam 2 Questions with 100- verified Answers latest update 2025 A+.

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NAGELHOUT-PHARM 2-Exam 2 Questions with 100- verified Answers latest update 2025 A+.

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NAGELHOUT-PHARM 2-Exam 2 Questions
with 100% verified Answers latest update
2025 A+


NMBs work at receptors


Ans: Nicotinic Cholinergic (sub-m)




Neurotransmitter of the NM junction


Ans: acetylcholine




Breaks down acetylcholine at the NM synapse/junction


Ans: acetylcholinesterase




Non-depolarizing agents are: agonists or antagonists

,Ans: Antagonist




Depolarizing agents act as: agonist or antagonist??


Ans: Agonist then antagonist




Onset time definition


Ans: time from drug administration to maximum effect




Clinical duration definition


Ans: time from drug administration to 25% recovery of twitch response




Total duration of action definition


Ans: time from drug administration to 90% recovery of twitch response

(point at which pt is recovered)




Recovery index definition

,Ans: time from 25% to 75% recovery of twitch response (how fast?)




Train of Four Index


Ans: 4th twitch of TOF/1st twitch of TOF




Muscle stimulated by ulnar nerve in TOF


Ans: Adductor pollicis




Best nerve/muscle to measure onset of NMB


Ans: Facial Nerve


Orbicularis Oculi (Corrugator supercilii = best)


(reflects diaphragm blockade)




Best nerve/muscle to measure emersion from NMB

, Ans: Ulnar Nerve


Adductor Pollicis




Single Twitch Test


Ans: 1.0 Hz


Single stimulus


Compares pre (baseline) and post NMB hand twitch




Train of Four Test


Ans: 4 - 2 Hz twitches


Compares 4th twitch to 1st twitch (fade)


Reflects 70-100% blockade




Double Burst Simulation (DBS) Test

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