TEST BANK For Katzung's Basic and Clinical Pharmacology, 16th Edition By {Todd W. Vanderah, 2024,} Verified Chapters 1 - 66, Complete Newest Version

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Basic and Clinical Pharmacology 16th Edition Katzung Trevor Test Bank
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Chapter 1. Introduction: The Nature of Drugs & Drug Development & Regulation
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1.
A nurse working in radiology administers iodine to a patient who is havin
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g a computed tomography (CT) scan. The nurse working on the oncology un
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it administers chemotherapy to patients who have cancer. At the Public Healt
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h Department, a nurse administers a measles-mumps-
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rubella (MMR) vaccine toa 14-month-
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old child as a routine immunization. Which branch of pharmacology best des
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cribes the actions of all three nurses?
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A) Pharmacoeconomics

B) Pharmacotherapeutics

C) Pharmacodynamics

D) Pharmacokinetics

Ans: B

Feedback:

Pharmacology is the study of the biologic effects of chemicals. Nurses are in
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volved with clinical pharmacology or pharmacotherapeutics, which is a bran
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ch of pharmacology that deals with the uses of drugs to treat, prevent, and di
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agnose disease. The radiology nurse is administering a drug to help diagnose
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a disease. The oncology nurse is administering a drug to help treat adisease.
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Pharmacoeconomics includes any costs involved in drug therapy.
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Pharmacodynamics involves how a drug affects the body an zf zf zf zf zf zf zf zf


dpharmacokinetics is how the body acts on the body.
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2.
A physician has ordered intramuscular (IM) injections of morphine, a nar
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cotic, every 4 hours as needed for pain in a motor vehicle accident victim.T
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he nurse is aware this drug has a high abuse potential. Under what category
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would morphine be classified?
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A) Schedule I zf




B) Schedule II zf




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C) Schedule III zf




D) Schedule IV zf




Ans: B

Feedback:

Narcotics with a high abuse potential are classified as Schedule II drugs bec
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ause of severe dependence liability. Schedule I drugs have high abuse poten
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tial and no accepted medical use. Schedule III drugs have a lesser abuse pot
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ential than II and an accepted medical use. Schedule IV drugs havelow abus
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e potential and limited dependence liability.
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3.
When involved in phase III drug evaluation studies, what responsibilit
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ieswould the nurse have?
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A) Working with animals who are given experimental drugs
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B) Choosing appropriate patients to be involved in the drug study
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C) Monitoring and observing patients closely for adverse effects zf zf zf zf zf zf zf




D) Conducting research to determine effectiveness of the drug zf zf zf zf zf zf zf




Ans: C

Feedback:

Phase III studies involve use of a drug in a vast clinical population in whic
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hpatients are asked to record any symptoms they experience while taking t
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hedrugs. Nurses may be responsible for helping collect and analyze the inf
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ormation to be shared with the Food and Drug Administration (FDA) butw
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ould not conduct research independently because nurses do not prescribe m
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edications. Use of animals in drug testing is done in the preclinical trials. S
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elect patients who are involved in phase II studies to participate in studies
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where the participants have the disease the drug is intended to treat. These
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patients are monitored closely for drug action and adverse effects. Phase I
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studies involve healthy human volunteers who are usually paid for their pa
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rticipation. Nurses may observe for adverse effects and toxicity.
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4.
What concept is considered when generic drugs are substituted for br
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andname drugs? fz zf




A) Bioavailability

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B) Critical concentration zf




C) Distribution

D) Half-life

Ans: A

Feedback:

Bioavailability is the portion of a dose of a drug that reaches the systemic c zf zf zf zf zf zf zf zf zf zf zf zf zf zf


irculation and is available to act on body cells. Binders used in a generic dr
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ug may not be the same as those used in the brand name drug. Therefore, th
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e way the body breaks down and uses the drug may differ, which may elimi
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nate a generic drug substitution. Critical concentration is the amount ofa dr
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ug that is needed to cause a therapeutic effect and should not differ betwee
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n generic and brand name medications. Distribution is the phase of pharma
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cokinetics, which involves the movement of a drug to the bodys tissues and
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is the same in generic and brand name drugs. A drugs half-
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life isthe time it takes for the amount of drug to decrease to half the peak le
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vel, which should not change when substituting a generic medication.
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5.
A nurse is assessing the patients home medication use. After listening to
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thepatient list current medications, the nurse asks what priority question?
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A) Do you take any generic medications?
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B) Are any of these medications orphan drugs?
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C) Are these medications safe to take during pregnancy?
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D) Do you take any over-the-counter medications?
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Ans: D

Feedback:

It is important for the nurse to specifically question use of over-the-
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counter medications because patients may not consider them important. The
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patient is unlikely to know the meaning of orphan drugs unless they too ar
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e health care providers. Safety during pregnancy, use of a generic medicatio
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n, or classification of orphan drugs are things the patient would be unable t
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o answer but could be found in reference books if the nurse wishes to resea
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rchthem. fz




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