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“CCRN Practice Questions with Correct Answers 2025/2026 | Updated Exam Prep”

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Prepare to succeed on the CCRN Exam (2025/2026) with this essential set of practice questions and verified correct answers. What’s included: CCRN practice questions written in real exam style All answers are 100% correct and verified Covers all AACN CCRN content areas: Cardiovascular & respiratory systems Neurology, renal, GI & multisystem issues Endocrine, hematology, and psychosocial care Professional caring & ethical practice Updated to match the 2025/2026 CCRN exam blueprint Perfect for self-testing, quick review, and last-minute exam prep Designed for critical care nurses aiming to pass the CCRN on their first attempt This resource is ideal for ICU, PCU, and critical care nurses preparing for AACN CCRN certification, offering exam-focused, high-yield practice material.

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CCRN Practice Questions with correct
answers 2025/2026
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The emergency drug therapy of choice for polymorphic ventricular tachycardia is:

A) Atropine
B) Amiodarone
C) Adenosine
D) Magnesium correct answers D) Magnesium (Correct)

You are caring for a patient post cardiac arrest who is receiving Targeted Temperature
Management (TTM). Which of the following clinical findings should you be concerned
about?

A) Heart rate of 30 bpm with a wide QRS and prolonged QT interval
B) Increasing diuresis
C) Increasing insulin requirements
D) Core body temperature of 34 C correct answers A) Heart rate of 30 bpm with a wide
QRS and prolonged QT interval (Correct)

The nurse is caring for a patient admitted for medical management of a dissecting
abdominal aortic aneurysm (AAA). The patient describes sudden onset severe
abdominal and back pain. Patient data: HR 120, BP 138/78 (98), RR 26, 94% SpO2 on
RA. Which of the following interventions is a priority of care for the registered nurse?

A) Administer PRN IV narcotic analgesia
B) Provide oxygen via nasal cannula
C) Administer PRN IV Beta-Blocker
D) Complete assessment of peripheral movement and sensation correct answers A)
Administer PRN IV narcotic analgesia (Correct)

Pharmaceutical management of hypertrophic cardiomyopathy should include:

A) Metoprolol (Lopressor)
B) Furosemide (Lasix)
C) Digoxin (Lanoxin)
D) Nitroprusside (Nipride) correct answers A) Metoprolol (Lopressor) (Correct)

The nurse is caring for a patient admitted for medical management of a dissecting
abdominal aortic aneurysm (AAA). The patient describes sudden onset severe
abdominal and back pain. Patient data: HR 120, BP 138/78 (98), RR 26, 94% SpO2 on
RA. Which of the following interventions is a priority of care for the registered nurse?

,A) Provide oxygen via nasal cannula
B) Administer PRN IV narcotic analgesia
C) Administer PRN IV Beta-Blocker |
D) Complete assessment of peripheral movement and sensation correct answers B)
Administer PRN IV narcotic analgesia (Correct)

Which set of hemodynamic parameters is associated with right sided heart failure?

A) Increased CO/CI, increased CVP, increased PAOP, increased SVR
B) Increased CO/CI, decreased CVP, increased PAOP, decreased SVR
C) Decreased CO/CI, increased CVP, decreased/normal PAOP, increased SVR
D) Decreased CO/CI, decreased CVP, decreased/normal PAOP, decreased SVR
correct answers C) Decreased CO/CI, increased CVP, decreased/normal PAOP,
increased SVR (Correct)

A patient returns to your unit after implantation of a permanent dual chamber
pacemaker. You note the patient is in atrial fibrillation. What would be the pacing mode
indicated for this patient?

A) DDD
B) VVI
C) DVI
D) VAT correct answers B) VVI (Correct)

Clinical signs of cardiogenic shock secondary to acute left ventricular failure include:

A) Hypotension, S4 heart sound, pericardial friction rub
B) S3 heart sound, Hypotension, systolic murmur
C) Diastolic murmur, S4 heart sound, Hypertension
D) Crackles, S3 heart sound, hypotension (Correct) correct answers D) Crackles, S3
heart sound, hypotension (Correct)

A patient with an acute anterior wall MI develops 2nd Degree Type II heart block. A
temporary transvenous pacing wire is inserted. You notice pacing spikes
indiscriminately during all phases of the cardiac cycle. Your best action would be:

A) Increase the sensitivity by lowering the mV
B) Decrease the sensitivity by raising the mV
C) Increase the milliamps (mA)
D) Decreased the milliamps (mA) correct answers A) Increase the sensitivity by
lowering the mV (Correct)

A patient is post-op day 3 for a cardiac transplant. During the night the patient develops
symptomatic bradycardia. Your best action to treat the bradycardia should include:

, A) Administer Atropine 1 mg IV and apply 100% O2
B) Connect epicardial pacing wires to a generator and pace the patient
C) Give Atropine and start and Isuprel infusion
D) Start a Dopamine infusion correct answers B) Connect epicardial pacing wires to a
generator and pace the patient (Correct)

A 55-year-old female presents to the ED anxious and SOB. Her 12 lead ECG reveals a
STEMI. Which of the following findings suggests an absolute contraindication for
thrombolytic therapy?

A) Dull chest pain, ST elevation in V4, V5, V6, new left bundle branch block |
B) History of cholecystectomy 2 weeks ago, ST elevation in V3, V4, V5 |
C) Sudden onset severe chest and back pain, uncontrolled BP 195/115, ST elevation II,
III, aVF, and a new diastolic murmur over the left sternal border
D) Left arm pain, BP 180/100 easily controlled on antihypertensive meds, ST elevation
in V1, V2 V3 correct answers C) Sudden onset severe chest and back pain,
uncontrolled BP 195/115, ST elevation II, III, aVF, and a new diastolic murmur over the
left sternal border (Correct)

A 68-year-old patient presents to your unit 9 days after a 3 vessel CABG complaining of
chest pain. A 12-lead ECG reveals non-specific ST elevation in leads V1 â€" V6.
Cardiac enzymes are not elevated. He states the pain is better when he sits up and
leans forward. This scenario is most consistent with:

A) Acute inferior wall MI
B) Post-operative cardiac tamponade
C) Pleural effusions
D) Pericarditis correct answers D) Pericarditis (Correct)

Signs of cardiac tamponade include:

A) Increased CVP, narrow pulse pressure, hypertension
B) Wide mediastinum on chest x-ray, narrow pulse pressure, hypotension
C) Widening pulse pressure, hypotension, elevated CVP
D) A fall in SBP > 10 mm Hg during inspiration, decreased CVP, hypotension correct
answers B) Wide mediastinum on chest x-ray, narrow pulse pressure, hypotension
(Correct)

A patient is admitted complaining of chest pain and nausea. The ECG monitor reveals
second-degree AV heart block, Type II. These findings are probably a result of
occlusion of which one of the following coronary arteries?

A) LAD
B) Circumflex
C) Posterior descending
D) RCA correct answers A) LAD (Correct)

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