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NR 565 Week 1, 2, 3 & 4 / NR565 Midterm
Exam Study Guide Advanced
Pharmacology Fundamentals Exam
Actual Questions with Correct Answers (Verified
Answers)- Chamberlain
TABLE OF CONTENTS
NR565 Midterm Exam Week 1 Study Guide Advanced Pharmacology Fundamentals
Ques & Ans
NR565 Midterm Exam Week 2 Study Guide Advanced Pharmacology Fundamentals
Ques & Ans
NR565 Midterm Exam Week 3 Study Guide Advanced Pharmacology Fundamentals
Ques & Ans
NR565 Midterm Exam Week 4 Study Guide Advanced Pharmacology Fundamentals
Ques & Ans
1/
71
, NR565 Midterm Exam Week 1 Study
Guide Advanced Pharmacology
Fundamentals Questions with Answers
(Verified Answers) Chamberlain
1.Pharmacokinetics:
Answer The study of drug absorption, distribution, metabolism, and
excretion in the body
"What the body does to the drug"
2.Factors that affect drug absorption (5):
Answer Rate of dissolution Surface area
Blood flow
Lipid
solubility PH
partitioning
3.Factors that affect drug distribution (4):
Answer Blood flow to tissues Ability to exit vascular
system
Blood-brain barrier
Protein-binding
2/
71
,capacity
4.Pharmacodynamics:
Answer The study of biochemical and physiologic effects of drugs on the
body and the molecular mechanisms by which those effects are
produced "What the body does to the drug"
5.Pharmaco-dynamics; 3 mechanisms of action:
Answer Receptor Enzyme
Non-selective interactions (i.e. chemo)
6.Types of drug therapy (7):
Answer Acute Maintenance
(HTN/bc) Supplemental (insulin)
Palliative
Supportive (IV
fluid)
Prophylactic
Empirical (broad-spectrum abx)
7.Idiosyncratic Effect:
Answer Unexpected response to medication
8.Tolerance:
Answer Declining response to a drug
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71
, 9.Dependence:
Answer Physiological/psychological need for a drug; needs drug for
normal function
10.Addiction:
Answer Compulsive use of a drug despite negative/dangerous effects
11.Drug interactions; drug-drug:
Answer When 2 drugs compete for metabolizing en- zymes
12.Drug interactions; food-drug:
Answer Grapefruit juice or leafy greens
13.Drug interactions; additive:
Answer 1+1 = 2; both provide intended effect
14.Drug interactions; antagonistic:
Answer 1+1 = <2; less than desired effect of one or both drugs
15.Drug interactions synergistic:
Answer 1+1 = >2; sum total effect is greater than if given alone (i.e.
lisinopril + HCTZ)
16.Drug interactions: incompatibility:
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71
NR 565 Week 1, 2, 3 & 4 / NR565 Midterm
Exam Study Guide Advanced
Pharmacology Fundamentals Exam
Actual Questions with Correct Answers (Verified
Answers)- Chamberlain
TABLE OF CONTENTS
NR565 Midterm Exam Week 1 Study Guide Advanced Pharmacology Fundamentals
Ques & Ans
NR565 Midterm Exam Week 2 Study Guide Advanced Pharmacology Fundamentals
Ques & Ans
NR565 Midterm Exam Week 3 Study Guide Advanced Pharmacology Fundamentals
Ques & Ans
NR565 Midterm Exam Week 4 Study Guide Advanced Pharmacology Fundamentals
Ques & Ans
1/
71
, NR565 Midterm Exam Week 1 Study
Guide Advanced Pharmacology
Fundamentals Questions with Answers
(Verified Answers) Chamberlain
1.Pharmacokinetics:
Answer The study of drug absorption, distribution, metabolism, and
excretion in the body
"What the body does to the drug"
2.Factors that affect drug absorption (5):
Answer Rate of dissolution Surface area
Blood flow
Lipid
solubility PH
partitioning
3.Factors that affect drug distribution (4):
Answer Blood flow to tissues Ability to exit vascular
system
Blood-brain barrier
Protein-binding
2/
71
,capacity
4.Pharmacodynamics:
Answer The study of biochemical and physiologic effects of drugs on the
body and the molecular mechanisms by which those effects are
produced "What the body does to the drug"
5.Pharmaco-dynamics; 3 mechanisms of action:
Answer Receptor Enzyme
Non-selective interactions (i.e. chemo)
6.Types of drug therapy (7):
Answer Acute Maintenance
(HTN/bc) Supplemental (insulin)
Palliative
Supportive (IV
fluid)
Prophylactic
Empirical (broad-spectrum abx)
7.Idiosyncratic Effect:
Answer Unexpected response to medication
8.Tolerance:
Answer Declining response to a drug
3/
71
, 9.Dependence:
Answer Physiological/psychological need for a drug; needs drug for
normal function
10.Addiction:
Answer Compulsive use of a drug despite negative/dangerous effects
11.Drug interactions; drug-drug:
Answer When 2 drugs compete for metabolizing en- zymes
12.Drug interactions; food-drug:
Answer Grapefruit juice or leafy greens
13.Drug interactions; additive:
Answer 1+1 = 2; both provide intended effect
14.Drug interactions; antagonistic:
Answer 1+1 = <2; less than desired effect of one or both drugs
15.Drug interactions synergistic:
Answer 1+1 = >2; sum total effect is greater than if given alone (i.e.
lisinopril + HCTZ)
16.Drug interactions: incompatibility:
4/
71
