NURS 615 PHARM EXAM 1 LATEST COMPLETE EXAM QUESTIONS AND
CORRECT ANSWERS
Nurse practitioner prescriptive authority is regulated by:
1. The National Council of State Boards of Nursing
2. The U.S. Drug Enforcement Administration
3. The State Board of Nursing for each state
4. The State Board of Pharmacy
3. The State Board of Nursing for each state
The benefits to the patient of having an Advanced Practice Registered Nurse (APRN) prescriber
include:
1. Nurses know more about Pharmacology than other prescribers because they take it both in
their basic nursing program and in their APRN program.
2. Nurses care for the patient from a holistic approach and include the patient in decision making
regarding their care.
3. APRNs are less likely to prescribe narcotics and other controlled substances.
4. APRNs are able to prescribe independently in all states, whereas a physician's assistant needs
to have a physician supervising their practice.
2. Nurses care for the patient from a holistic approach and include the patient in decision making
regarding their care.
The route of excretion of a volatile drug will likely be the:
1. Kidneys
2. Lungs
3. Bile and feces
4. Skin
2. Lungs
Phase I oxidative-reductive processes of drug metabolism require certain nutritional elements.
Which of the following would reduce or inhibit this process?
1. Protein malnutrition
2. Iron-deficiency anemia
3. Both 1 and 2
4. Neither 1 nor 2
3. Both 1 and 2
,The time required for the amount of drug in the body to decrease by 50% is called:
1. Steady state
2. Half-life
3. Phase II metabolism
4. Reduced bioavailability time
2. Half-life
An agonist activates a receptor and stimulates a response. When given frequently over time, the
body may:
1. Upregulate the total number of receptors
2. Block the receptor with a partial agonist
3. Alter the drug's metabolism
4. Downregulate the numbers of that specific receptor
4. Downregulate the numbers of that specific receptor
Drug antagonism is best defined as an effect of a drug that:
1. Leads to major physiological and psychological dependence
2. Is modified by the concurrent administration of another drug
3. Cannot be metabolized before another dose is administered
4. Leads to a decreased physiological response when combined with another drug
2. Is modified by the concurrent administration of another drug
Instructions to a client regarding self-administration of oral enteric-coated tablets
should include which of the following statements?
1. "Avoid any other oral medicines while taking this drug."
2. "If swallowing this tablet is difficult, dissolve it in 3 ounces of orange juice."
3. "The tablet may be crushed if you have any difficulty taking it."
4. "To achieve best effect, take the tablet with at least 8 ounces of fluid."
4. "To achieve best effect, take the tablet with at least 8 ounces of fluid."
The major reason for not crushing a sustained-release capsule is that, if crushed, the coated beads
of the drugs could possibly result in:
1. Disintegration
2. Toxicity
3. Malabsorption
4. Deterioration
,2. Toxicity
Which of the following substances is the most likely to be absorbed in the
intestines rather than in the stomach?
1. Sodium bicarbonate
2. Ascorbic acid
3. Salicylic acid
4. Glucose
1. Sodium bicarbonate
Clinical judgment in prescribing includes:
1. Factoring in the cost to the patient of the medication prescribed
2. Always prescribing the newest medication available for the disease process
3. Handing out drug samples to poor patients
4. Prescribing all generic medications to cut costs
1. Factoring in the cost to the patient of the medication prescribed
Criteria for choosing an effective drug for a disorder include:
1. Asking the patient what drug, they think would work best for them
2. Consulting nationally recognized guidelines for disease management
3. Prescribing medications that are available as samples before writing a prescription
4. Following U.S. Drug Enforcement Administration guidelines for prescribing
2. Consulting nationally recognized guidelines for disease management
Nurse practitioner practice may thrive under health-care reform because of:
1. The demonstrated ability of nurse practitioners to control costs and improve patient outcomes
2. The fact that nurse practitioners will be able to practice independently
3. The fact that nurse practitioners will have full reimbursement under health-care reform
4. The ability to shift accountability for Medicaid to the state level
1. The demonstrated ability of nurse practitioners to control costs and improve patient outcomes
A patient's nutritional intake and laboratory results reflect hypoalbuminemia. This
is critical to prescribing because:
1. Distribution of drugs to target tissue may be affected.
2. The solubility of the drug will not match the site of absorption.
3. There will be less free drug available to generate an effect.
4. Drugs bound to albumin are readily excreted by the kidneys.
, 1. Distribution of drugs to target tissue may be affected.
Drugs that have a significant first-pass effect:
1. Must be given by the enteral (oral) route only
2. Bypass the hepatic circulation
3. Are rapidly metabolized by the liver and may have little if any desired action
4. Are converted by the liver to more active and fat-soluble forms
3. Are rapidly metabolized by the liver and may have little if any desired action
Medroxyprogesterone (Depo Provera) is prescribed intramuscularly (IM) to create a storage
reservoir of the drug. Storage reservoirs:
1. Assure that the drug will reach its intended target tissue
2. Are the reason for giving loading doses
3. Increase the length of time a drug is available and active
4. Are most common in collagen tissues
3. Increase the length of time a drug is available and active
The NP chooses to give cephalexin every 8 hours based on knowledge of the drug's:
1. Propensity to go to the target receptor
2. Biological half-life
3. Pharmacodynamics
4. Safety and side effects
2. Biological half-life
Azithromycin dosing requires that the first day's dosage be twice those of the other
4 days of the prescription. This is considered a loading dose. A loading dose:
1. Rapidly achieves drug levels in the therapeutic range
2. Requires four- to five-half-lives to attain
3. Is influenced by renal function
4. Is directly related to the drug circulating to the target tissues
1. Rapidly achieves drug levels in the therapeutic range
The point in time on the drug concentration curve that indicates the first sign of a therapeutic
effect is the:
1. Minimum adverse effect level
2. Peak of action
CORRECT ANSWERS
Nurse practitioner prescriptive authority is regulated by:
1. The National Council of State Boards of Nursing
2. The U.S. Drug Enforcement Administration
3. The State Board of Nursing for each state
4. The State Board of Pharmacy
3. The State Board of Nursing for each state
The benefits to the patient of having an Advanced Practice Registered Nurse (APRN) prescriber
include:
1. Nurses know more about Pharmacology than other prescribers because they take it both in
their basic nursing program and in their APRN program.
2. Nurses care for the patient from a holistic approach and include the patient in decision making
regarding their care.
3. APRNs are less likely to prescribe narcotics and other controlled substances.
4. APRNs are able to prescribe independently in all states, whereas a physician's assistant needs
to have a physician supervising their practice.
2. Nurses care for the patient from a holistic approach and include the patient in decision making
regarding their care.
The route of excretion of a volatile drug will likely be the:
1. Kidneys
2. Lungs
3. Bile and feces
4. Skin
2. Lungs
Phase I oxidative-reductive processes of drug metabolism require certain nutritional elements.
Which of the following would reduce or inhibit this process?
1. Protein malnutrition
2. Iron-deficiency anemia
3. Both 1 and 2
4. Neither 1 nor 2
3. Both 1 and 2
,The time required for the amount of drug in the body to decrease by 50% is called:
1. Steady state
2. Half-life
3. Phase II metabolism
4. Reduced bioavailability time
2. Half-life
An agonist activates a receptor and stimulates a response. When given frequently over time, the
body may:
1. Upregulate the total number of receptors
2. Block the receptor with a partial agonist
3. Alter the drug's metabolism
4. Downregulate the numbers of that specific receptor
4. Downregulate the numbers of that specific receptor
Drug antagonism is best defined as an effect of a drug that:
1. Leads to major physiological and psychological dependence
2. Is modified by the concurrent administration of another drug
3. Cannot be metabolized before another dose is administered
4. Leads to a decreased physiological response when combined with another drug
2. Is modified by the concurrent administration of another drug
Instructions to a client regarding self-administration of oral enteric-coated tablets
should include which of the following statements?
1. "Avoid any other oral medicines while taking this drug."
2. "If swallowing this tablet is difficult, dissolve it in 3 ounces of orange juice."
3. "The tablet may be crushed if you have any difficulty taking it."
4. "To achieve best effect, take the tablet with at least 8 ounces of fluid."
4. "To achieve best effect, take the tablet with at least 8 ounces of fluid."
The major reason for not crushing a sustained-release capsule is that, if crushed, the coated beads
of the drugs could possibly result in:
1. Disintegration
2. Toxicity
3. Malabsorption
4. Deterioration
,2. Toxicity
Which of the following substances is the most likely to be absorbed in the
intestines rather than in the stomach?
1. Sodium bicarbonate
2. Ascorbic acid
3. Salicylic acid
4. Glucose
1. Sodium bicarbonate
Clinical judgment in prescribing includes:
1. Factoring in the cost to the patient of the medication prescribed
2. Always prescribing the newest medication available for the disease process
3. Handing out drug samples to poor patients
4. Prescribing all generic medications to cut costs
1. Factoring in the cost to the patient of the medication prescribed
Criteria for choosing an effective drug for a disorder include:
1. Asking the patient what drug, they think would work best for them
2. Consulting nationally recognized guidelines for disease management
3. Prescribing medications that are available as samples before writing a prescription
4. Following U.S. Drug Enforcement Administration guidelines for prescribing
2. Consulting nationally recognized guidelines for disease management
Nurse practitioner practice may thrive under health-care reform because of:
1. The demonstrated ability of nurse practitioners to control costs and improve patient outcomes
2. The fact that nurse practitioners will be able to practice independently
3. The fact that nurse practitioners will have full reimbursement under health-care reform
4. The ability to shift accountability for Medicaid to the state level
1. The demonstrated ability of nurse practitioners to control costs and improve patient outcomes
A patient's nutritional intake and laboratory results reflect hypoalbuminemia. This
is critical to prescribing because:
1. Distribution of drugs to target tissue may be affected.
2. The solubility of the drug will not match the site of absorption.
3. There will be less free drug available to generate an effect.
4. Drugs bound to albumin are readily excreted by the kidneys.
, 1. Distribution of drugs to target tissue may be affected.
Drugs that have a significant first-pass effect:
1. Must be given by the enteral (oral) route only
2. Bypass the hepatic circulation
3. Are rapidly metabolized by the liver and may have little if any desired action
4. Are converted by the liver to more active and fat-soluble forms
3. Are rapidly metabolized by the liver and may have little if any desired action
Medroxyprogesterone (Depo Provera) is prescribed intramuscularly (IM) to create a storage
reservoir of the drug. Storage reservoirs:
1. Assure that the drug will reach its intended target tissue
2. Are the reason for giving loading doses
3. Increase the length of time a drug is available and active
4. Are most common in collagen tissues
3. Increase the length of time a drug is available and active
The NP chooses to give cephalexin every 8 hours based on knowledge of the drug's:
1. Propensity to go to the target receptor
2. Biological half-life
3. Pharmacodynamics
4. Safety and side effects
2. Biological half-life
Azithromycin dosing requires that the first day's dosage be twice those of the other
4 days of the prescription. This is considered a loading dose. A loading dose:
1. Rapidly achieves drug levels in the therapeutic range
2. Requires four- to five-half-lives to attain
3. Is influenced by renal function
4. Is directly related to the drug circulating to the target tissues
1. Rapidly achieves drug levels in the therapeutic range
The point in time on the drug concentration curve that indicates the first sign of a therapeutic
effect is the:
1. Minimum adverse effect level
2. Peak of action
