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2025/2026 HESI RN Pharmacology Exam Test Bank Questions & Answers (Actual Exam Updated 2025))

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2024/2025 HESI RN Pharmacology Exam Test Bank Questions & Answers (Actual Exam)-Following the administration of sublingual nitroglycerin to a client experiencing an acute anginal attack, which assessment finding indicates to the nurse that the desired effect has been achieved? A. Client states chest pain is relieved B. Client's pulse decreases from 120 to 90 C. Client's systolic blood pressure decreases from 180 to 90 D. Clients SaO2 level increases from 92% to 96% - A. Client states chest pain is relieved Nitroglycerin reduces myocardial oxygen consumption which decreases ischemia and reduces chest pain A client with hyperlipidemia recieves a prescription for niacin (niaspan). which client teaching is most important for the nurse to provide a. expected duration of flushing b. symptoms of hyperglycemia c. diets that minimize gi irritation d. comfort measure for pruritis - A. expected duration of flushing Flushing of the face and neck, lasting up to an hour, is a frequent reason for discontinuing niacin. inclusion of this effect in client teaching may promote compliance in taking the med. When assessing an adolescent who recently overdosed on acetaminophen (tylonel), it is most important for the nurse to assess for pain in which area of the body a. flank b. abdomen c. chest d. head - B. abdomen Acetaminophen toxicity an result in liver damage; therefore, it is especially important for the nurse to assess for pain in the right upper quadrant of the abdomen (which might indicated liver damage) A client is admitted to the coronary care unit with a medical diagnosis of acute myocardial infarction. which medication prescription decreases both preload and afterload a. nitroglycerin b. propranolol c. propranolol d. captopril - A. nitroglycerin Nitroglycerin is a nitrate that causes peripheral vasodilation and decreases contractility, thereby decreasing both preload and afterload A clietn is being treated for hyperthyroidism with propylthiouracil (PTU). The nurse knows that the action of this drug is to A. decrease the amount of the thyroid-stimulating hormone circulating in the blood B. increase the amount of thyroid-stimulating hormone circulating in the blood C. increase the amount of T4 and decrease the amount of T3 produced by the thyroid D. inhibit synthesis of T3 and T4 by the thyroid gland - D. Inhibit synthesis of T3 and T4 by the thyroid gland PTU is an adjunct therapy used to control hyperthyroidism by inhibiting production of thyroid hormones. It is often prescribed in prep for thyroidectomy or radioactive iodine therapy Which change in data indicates to the nurse the desired effect of the angiotensin II receptor antagonist has been achieved A. Dependent edema reduced form +3 to +1 B. Serum HDL increased from 35 to 55mg/dl C. PUlse rate reduced from 150 to 90 beats/min D. Blood pressure reduced from 160/90 to 130/80 - D. Blood pressure reduced from 160/90 to 130/80 Angiotensin II receptor antagonist (blocker), prescribed from treatment of HTN. The desired effect is a decrease in blood pressure. Which instructions should the nurse give to a femail client who just recieved a prescription for oral metronidazole (flagyl) for treatment of trichomonas vaginalis (select all that apply) A. Increase fluid intake, especially cranberry juice B. Do not abruptly discontinue the medication; taper use C. Check blood pressure daily to detect hypertension D. Avoid drinking alcohol while taking this medication E. Use condoms until treatment is completed F. Ensure that all sexual partners are treated at the same time - ADEF A. Increase fluid intake, especially cranberry juice D. Avoid drinking alcohol while taking this medication E. Use condoms until treatment is completed F. Ensure that all sexual partners are treated at the same time The nurse is transcribing a new prescription for spironolactone (aldactone) for a client who receives an angiotensin-converting enzyme inhibitor. Which action should the nurse implement A. verify both prescriptions with the HCP B. report the med interactions to the nurse manager C. hold the ACE inhibitor and give the new prescription D. Transcribe and send the prescription to the pharmacy - A. verify both prescriptions with the HCP The concomitant use of an ACE inhibitor and a potassium-sparing diuretic such as spironolactone, should be given with caution b/c the two drugs may interact to cause an elevation in serum potassium levels. A client has myxedema, which results from a deficiency of thyroid hormone synthesis in adults. The nurse knows that which medication should be contraindicated for this client? A. Liothyronine (cytomel) to replace iodine B. Furosemide (Lasix) for relief of fluid retention C. Pentobarbital sodium for sleep D. Nitroglycerin for angina pain - C. Pentobarbital sodium for sleep Persons with myxedema are dangerously hypersensitive to narcotics, barbiturates, and anesthetics. They do not tolerate liothyronine and usually receive iodine replacement therapy. These clients are also suceptable to heart problems such as angina for which nitroglycerine would be indicated and and congestive heart failure for which furosemide would be indicated A client has a continuous IV infusion of dopamine and an IV of normal saline at 50ml/hour. The nurse notes that the client's urinary output has been 20ml/hour for the last two hours. Which intervention should the nurse initiate? A. stop the infusion of dopamine B. change the normal saline to a keep open rate C. replace the urinary catheter D. notify the healthcare provider of the urinary output. - D. Notify the healthcare provider of the urinary output.

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HESI PHARMACOLOGY PRACTICE EXAM
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QUESTIONS AND ANSWERS (2025)
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THIS EXAM CONTAINS:
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 Hesi Pharmacology
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 Practice Exam
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 Questions And Answers
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1|Pag
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,1. Followingtheadministrationofsublingualnitroglycerintoaclientexperi- encing an acute anginal attack, v v v v v



v which assessment finding indicates to the nurse that the desired effect has been achieved?
v v v v v v v v v v v v v




A. Client states chest pain is relieved
v v v v v




B. Client's pulse decreases from 120 to 90
v v v v v v




C. Client's systolic blood pressure decreases from 180 to 90
v v v v v v v v




D. Clients SaO2 level increases from 92% to 96%
v v v v v v v




..ANS>> A.nitroglycerin reduces mycocardialoxygenconsumptionwhichdecreasesischemiaandreduces
i v v v v




v chest pain
v




2. Aclientwithhyperlipidemia recievesa prescriptionfor niacin (niaspan). i v v i v which client teaching is most
v v v v v



v important for the nurse to provide v v v v v




a. expected duration of flushing v v v




b. symptoms of hyperglycemia v v




c. diets that minimize gi irritation
v v v v




d. comfortmeasure for pruritis v v




..ANS>> A.flushing oftheface andneck,lastingupto an hour, is a frequent reason for discontinuing niacin.
i v v v v v v v v v v v v




inclusion ofthis effect inclietn teaching may promote compliance in taking the med.
v v v v v v v v v v v v




3. Whenassessing an adolescent who recently overdosed onacetaminophen (tylonel), it is most important for
v v v v v v v v v v v v



v thenursetoassessforpaininwhichareaof the body v v




a. flank
b. abdomen
c. chest
d. head
..ANS>>B.acetaminophentoxicistyanresultin liverdamage;therefore,itisespe- cially important for the nurse to
i i v v v v v v v




v assess for pain in the right upper quadrant of the abdomen (which might indicated liver damage)
v v v v v v v v v v v v v v v




2|Pag
v v v v v

,4. A v client is admitted to the coronary care unit with a medical diagnosis of acute
v v v v v v v v v v v v v



v myocardial infarction.whichmedication prescriptiondecreasesboth preload and afterload
v i v v v




a. nitroglycerin
b. propranolol
c. propranolol
d. captopril
..ANS>> A.nitroglycerin isa nitrate that causes peripheralvasodilationand decreases contractility, thereby
i v v v v v v v v v




v decreasing both preload andafterload
v v v




5. Aclientisbeingtreatedforhyperthyroidismwithpropylthiouracil(PTU).The nurse knows that the action of
i i i v v v v v v



v this drug is to
v v v




A. decreasethe amountof thethyroid-stimulatinghormonecirculatinginthe blood
v v v




B. increase the amount ofthyroid-stimulating hormone circulating in the
v v v v v v v




3|Pag
v v v v v

, blood

C. increasethe amount ofT4 anddecrease the amount ofT3 produced by the thyroid
v v v v v v v v v v




D. inhibit synthesis ofT3 andT4 by the thyroid gland
v v v i v v v v




..ANS>> D.PTU is an adjunct therapyusedtocontrolhyperthyroidismbyinhibitingproductionofthyroidhormones.
iv v v v v i i i i




v It is often prescribed in prep for thyroidectomy or radioactive iodine therapy
v v v v v v v v v v v




6. Which change in data indicates to the nurse thedesired effect ofthe angiotensin II receptor
v v v v v v v v v v v v v



v antagonist has been achieved v v v




A. Dependent edema reduced form +3 to +1 v v v v v v




B. Serum HDL increased from 35 to 55mg/dl
v v v v v v




C. PUlse rate reduced from 150 to 90 beats/min
v v v v v v v




D. Bloodpressurereducedfrom160/90 to130.80 v




..ANS>>D.angiotensinIIreceptor antagonist(blocker), prescribed fromtreatment of HTN.The desired
i v v v v v v




v effect is a decrease in blood pressure.
v v v v v v




7. Which instructions should the nurse give to a female client who just recieveda prescriptionfororal
v v v v v v v v v v v v v v



v metronidazole (flagyl) fortreatment oftri- chomonas vaginalis (select all that apply)
v v v v v v v v v




A. increase fluid intake, especially cranberry juice
v v i v v




B. Do not abruptly discontinue the medication;taper use
v v v v v v




C. Check blood pressure daily to detect hypertension
v v v v v v




D. Avoiddrinking alcohol while taking thismedication v v v v




E. Use condoms until treatment is completed
v v v v v




F. Ensure that all sexual partners are treated at the same time
v v v v v v v v v v




i..ANS>> ADEF i v




4|Pag
v v v v v

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