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3P Exam Study APEA – Comprehensive Q&A Review of Pathology, Pharmacology, and Clinical Management

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This document is a detailed question-and-answer style study resource for the 3P Exam, based on APEA material. It covers high-yield topics across internal medicine, pediatrics, obstetrics, gynecology, psychiatry, dermatology, cardiology, neurology, infectious diseases, and pharmacology. Each entry includes hallmark signs, diagnostic methods, treatments, and contraindications, making it an essential study tool for exam preparation.

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3P Exam Study APEA


#1 Risk Factor for Testicular & Penile Cancer - ANS Cryptochordism

1st line Treatment of UTI in pregnancy - ANS Nitrofurantoin (Macrobid)

Abruptio Placentae (Placental Abruption) - ANS Absent/Profuse vaginal
bleeding, abnormal painful uterine contractions, uterine tenderness, rigid &
board-like uterus on palpatation

Acromegaly Presentation - ANS Bone overgrowth, big hands, face, and feet
Cause - Pituitary Gland overproduction
Gigantism = Pediatrics
Acromegaly/Giantism = Adults

Acute Bacterial Rhinosinusitis treatment - ANS If patient is allergic to PCN,
then Doxycycline is the best alternative

Acute Lymphoblastic Leukemia (ALL) - ANS Most common Leukemia in
children
S&S:
Fever, Thrombocytopenia, Anemia, Gingival Hyperplasia (swelling), Bone pain

Acute Sinusitis Tx for Adults & Pediatrics - ANS - Viral is symptomatic
treatment only
- Bacterial tx is Amoxicillin 1st line if symptoms >10 days and include purulent nasal
discharge, fever, unilateral face/tooth pain

Adam's Sign - ANS Evaluation for scoliosis.
Negative for functional scoliosis if curve straightens out
Positive for structural scoliosis if curve remains

Adjust meds in kidney disease when? - ANS If GFR is less than 60

Allergic Rhinitis - ANS Eosinophils elevated in Allergies, Wheezes, Parasites
Tx is Fluticasone (Flonase)

Anxiety Treatment - ANS busparone (Buspar)
*Anxiety & Depression coexist - use GAD 7 scale to dx

Aortic Regurgitation presentation - ANS Angina & Dyspnea

,Assessment of a 4yr old visual acuity results in 20/30 in L eye and 20/40 in R eye -
ANS Means vision is normal for his age. Children at 6 years can normally achieve
20/20 vision.

Asthma - Mild Intermittent - ANS Symptoms present < 2 days/week, or < 2
nights/month

Asthma - Mild Persistent - ANS Symptoms present > 2days/week but not
everyday, 3-4 nighttime awakenings/month

Asthma - Moderate Persisent - ANS Daily symptoms or more than 3-4 nights
per month

Asthma - Severe Persistent - ANS Continuous symptoms, frequent nocturnal
symptoms, <60% FEV

Asthma Diagnostic - ANS Spirometry, Pulmonary Function Tests (PFTs),
Allergy Testing, Peak Flow

Bacterial Vaginosis - ANS Not an STI. Common sexually active females.
S&S - Fishy smell, watery discharge, clue cells, increased alkalosis
Tx: metronidazole (Flagyl), Lactobacillus Probiotics

Barlows Maneuver - ANS Feeling of a slip of the femoral head slips away from
the Acetabulum (toward the butt)

Beer's List - ANS a list of drugs for which you should not give or monitoring is
especially important in elderly patients
Anti-cholinergics, anti-spasmotics, scopolamine, meclizine, promethazine
High risk of confusion, dry mouth, constipation.

Benign Prostatic Hyperplasia (BPH) - ANS Enlargement of the prostate which
narrows the urethral lumen.
Risk Factors: Elevated PSA, Blacks & Asians, Age

Beta Thalassemia - ANS Genetic disorder where there is decreased or absent
production of hemoglobin.
Common amongst Mediterranea descent
Causes microcytic hypochromic anemia
Tx: Desferal which removes excess iron

BPH assessment findings - ANS Firm smooth enlarged prostate.

, BPH S&S - ANS Dribbling after urination
Excessive nocturnal urination
Frequency
Sense of incomplete bladder emptying
Incontinence
Sexual dysfunction

BPH Treatment - ANS *Gold standard TURP
Medications
Alpha 1 adrenergic antagonist (tamsulosin) - relaxes smooth muscle in the prostate -
immediate relief
5 Alpha Reductase inhibitor (finasteride) - inhibits conversion of testosterone to DHT
- Long term and takes 6-12months to start working

Breast Cancer - ANS painless, firm/fixed mass, skin or nipple changes, nipple
discharge, swelling, lymphnode enlargement.

Bulimia Presentation - ANS Recurrent episodes of eating, binging, and
purging.
+ Russell's Sign - knuckle scarring from induced vomiting

Bulimia Treatment - ANS SSRIs i.e. fluoxetine (Prozac) & sertraline (Zoloft)

Chlamydia - ANS Most Common STI in US.
S&S - Genital Ulceration, Lymphadenopathy, Occular Trachoma, Proctitis, Cervical
Motion Tenderness, Assymptomatic. Can cause PID

Chlamydia Diagnostic & Treatment - ANS Gold Standard - Nuclieic Acid
Amplification Test (NAAT) & Gen-Probe Assay
Tx: Azithromycin in pregnant patients, Amoxicillin if allergic.

Chron's Disease S&S - ANS Chronic Bloody Diarrhea
Fatigue, Abdomnial Pain
Weight Loss/Fever
Skip Lesions, Cobblestone appearance
Fistulas are common
Slow progressive inflammation of small/large intestine
Tx is Budesonide 5-aminosalicylates

Cirrhosis S&S - ANS Coagulopathy
Thrombocytopenia in early stages
Bleeding Varices
Hepatic Encephalopathy
ALOC and Tremors

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