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1. dNTP despite the diversity, cells resemble each other to an astonishing degree
in their chemistry. For example, only four ______ are used to make DNA.
2. nuclear envelope the _______ ______ is made up of two concentric membranes and is
continuous with the membrane of theendoplasmic reticulum.
3. salt ionic bonds form a ____.
4. positively charged the side chain of the amino acid R under pH 7 is ____
5. tyrosine (Y) this amino acid side chain can be phosphorylated by a protein kinase
6. alpha helix hydrogen bonds are essential to form a(n) ______
7. protein phosphatase which of the following protein is necessary to stop a mitogenic signaling
by dissociating a SH2 domain containing protein (Grb2) from phospho-
rylated Growth factor receptor?
8. phospho-tyrosine and which of the following is mainly mediated by an ionic bond?
SH2 domain association
9. 10^8 liters/mole protein A binds to protein B to form a complex, AB. At equilibrium in a cell,
A, B, and AB concentrations are all at 10 nM. Calculate the equilibrium
constant for the reaction A + B <--> AB
10. myosin II choose an example of a motor protein.
11. insulin choose an example of a protein that is a signaling molecule
12. EGFR choose an example of a protein of which a signaling receptor
13. left-handedness which of the following is not a feature commonly observed in α helices?
14. colied-coil patterns which of the following is not a feature commonly observed in β sheets?
, Cell Bio Practice Exam 1 Dr. Leung Kim FIU
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15. secondary structure the α helices and β sheets are examples of protein _____
16. domain a protein _____ is the modular unit from which many larger single-chain
proteins are constructed.
17. myosin II which of the following molecule shows a significant conformational
change in response to binding to ATP?
18. actin which of the following proteins will form a globular protein molecule?
19. the two DNA strands in a DNA double helix, ___.
run antiparallel
20. gene silencing the N-terminal tail of histone H3 can be extensively modified, and de-
pending on the number, location, and combination of these modifica-
tions, these changes may promote the formation of heterochromatin.
What is theresult of heterochromatin formation?
21. lysine 9 trimethylation methylation and acetylation are common changes made to histone H3,
and the specific combination of these changes is sometimes referred to
as the "histone code." Which of the following patterns will probably lead
to gene silencing?
22. they use energy derived which of the following best describes the mechanism by which chro-
from ATP hydrolysis to matin-remodeling complexes "loosen" theDNA wrapped around the
change the relative po- core histones?
sition of the DNA and
the core histone oc-
tamer
23. H3 lysine 9 trimethyla- most eukaryotic cells only express 20-30% of the genes they possess. The
tion formation of heterochromatin
maintains the other genes in a transcriptionally silent (unexpressed)