AANP Actual Exam
AANP Actual Exam, Practice Exam And
Study Guide Newest 2025/2026 With
Complete Questions And Correct
Answers |Already Graded A+||Brand
New Version!
Mrs. Griffin is a 46-year-old woman with type 2 diabetes mellitus who is using metformin and a
single 10-unit daily dose of the long-acting insulin, glargine. Her fasting blood glucose has been
between 120-140 mg/dL (6.7-7.8 mmol/L). Which of the following best describes the next step in
her therapy?
Continue on the current glargine dose
Increase her glargine dose by 2 units per day
Increase her glargine dose by 4 units per day
Increase her glargine dose by 6 units per day
- Correct Answer :Increase her glargine dose by 2 units per day
The current approach to the management of type 2 diabetes mellitus is that when added,
glargine insulin should begin at 10 units daily and then titrated up or down to reach a target
fasting blood glucose of approximately 100 mg/dL.
-When fasting blood glucose remains 141-180 mg/dL, dose should be increased by 4 units.
-If the fasting glucose is 120-140 mg/dL, the dose should be increased by 2 units
-when it is >180 mg/dL, the dose should be increased by 6 units.
The use of which of the following medication classes has the potential for causing the greatest
reduction in A1c for a 45-year-old man with newly-diagnosed type 2 diabetes mellitus and a
current A1c of 10.5%?
SGLT2 inhibitor
Thiazolidinedione
DPP-4 inhibitor
Insulin formulation
- Correct Answer :Insulin formulation
A+ TEST BANK 1
, AANP Actual Exam
All other PO medications only reduce the A1C by 1-2%. For patients with >10% need to start with
insulin and reevaluate after several months.
Which of the following characteristics applies to type 2 diabetes mellitus?
a. Inactivity is a potent risk factor for the condition.
b. Genetic influences are associated with type 1 but not type 2 diabetes mellitus risk.
c. Exogenous insulin is consistently needed throughout the course of the disease.
d. "Pear-shaped" body habitus is often noted.
- Correct Answer :a. Inactivity is a potent risk factor for the condition.
diabetes mellitus is a complex metabolic disorder characterized by a variety of risk factors
including inactivity, obesity, genetics, medication, and aging.
You are teaching a 62-year-old patient with type 2 diabetes mellitus about using mealtime insulin
to help with the management of post-prandial hyperglycemia. You describe a situation where
blood sugar is between 200 and 250 mg/dL (11.1?13.9 mmol/L) and advise the appropriate dose
of rapid-acting insulin to attain a goal of <150 mg/dL (8.3 mmol/L) is:
1 unit.
2 units.
4 units.
8 units.
- Correct Answer :2 units.
One unit of rapid-acting insulin will result in a blood sugar decrease of approximately 50 mg/dL
(2.78 mmol/L). Therefore, in the example above, 2 units will be needed to attain the goal of <150
mg/dL.
Which of the following best describes the appropriate use of insulin lispro?
In an insulin pump
As a mealtime insulin
As a basal insulin
To prevent the Somogyi effect
A+ TEST BANK 2
, AANP Actual Exam
- Correct Answer :As a mealtime insulin
onset 15-30 minutes after administration and a peak of 30 minutes to 2.5 hours.
When prescribing glargine or detemir, the clinician should consider that:
-Its mechanism of action differs from that of other insulins.
-It is used as basal insulin.
-It reaches peak effect at 12 hours after injection.
-It can be mixed in the same syringe with rapid-acting insulin.
- Correct Answer :-It is used as basal insulin.
Using metformin in a 62-year-old person who has a 20-year history of T2DM and a GFR=28
mL/min/1.73 m2 can potentially increase the risk of:
QTc prolongation.
Renal failure.
Poor glycemic control.
Lactic acidosis
. - Correct Answer :Lactic acidosis.
ther risk factors for lactic acidosis with metformin use include concomitant use of certain
medications (e.g., topiramate),
-age 65 years and older
-having a radiological study with contrast, surgery and other procedures
hypoxic states (e.g., acute congestive heart failure)
excessive alcohol intake, and hepatic impairment.
The results of a radioactive iodine uptake scan of a 52-year-old woman with a thyroid mass
reveal a cold spot. This finding is most consistent with:
Amiodarone-induced thyroid disease.
Thyroid cyst.
Metabolically-active thyroid nodule.
Graves' disease
. - Correct Answer :Thyroid cyst.
Nonfunctional tissue does not uptake iodine, and on a radioactive iodine uptake scan a cyst will
appear as nonfunctional or "cold."
A+ TEST BANK 3
, AANP Actual Exam
Amiodarone-induced thyroid disease, active thyroid nodule, and Graves' disease are all
conditions of increased gland function, and nodules would scan as hyperfunctioning or "hot."
A 27-year-old woman is newly diagnosed with Graves' disease that will be treated with
methimazole or propylthiouracil. In counseling the patient, the NP mentions a potential risk for:
Renal dysfunction.
Weight gain.
Liver toxicity.
Peripheral neuropathy.
- Correct Answer :Liver toxicity.
Refer to endocrinology
Which of the following is most consistent with findings in thyroid cancer?
Hard, fixed thyroid mass of 2 cm in diameter
"Hot spot" on thyroid scan
Abnormally low TSH
Presence of TPO antibodies
- Correct Answer :Hard, fixed thyroid mass of 2 cm in diameter
A hard, fixed mass larger than 1-1.5 cm should raise suspicion of malignancy and be referred for
fine-needle aspiration biopsy.
Oral antimicrobials commonly used to treat H. pylori gastrointestinal tract infection include all of
the following except:
Metronidazole.
Vancomycin.
Clarithromycin.
Amoxicillin.
- Correct Answer :Vancomycin.
Amoxicillin and metronidazole are effective agents, and H. pylori resistance to these agents is
uncommon. Clarithromycin can also be used though resistance to this agent is increasing.
A+ TEST BANK 4
AANP Actual Exam, Practice Exam And
Study Guide Newest 2025/2026 With
Complete Questions And Correct
Answers |Already Graded A+||Brand
New Version!
Mrs. Griffin is a 46-year-old woman with type 2 diabetes mellitus who is using metformin and a
single 10-unit daily dose of the long-acting insulin, glargine. Her fasting blood glucose has been
between 120-140 mg/dL (6.7-7.8 mmol/L). Which of the following best describes the next step in
her therapy?
Continue on the current glargine dose
Increase her glargine dose by 2 units per day
Increase her glargine dose by 4 units per day
Increase her glargine dose by 6 units per day
- Correct Answer :Increase her glargine dose by 2 units per day
The current approach to the management of type 2 diabetes mellitus is that when added,
glargine insulin should begin at 10 units daily and then titrated up or down to reach a target
fasting blood glucose of approximately 100 mg/dL.
-When fasting blood glucose remains 141-180 mg/dL, dose should be increased by 4 units.
-If the fasting glucose is 120-140 mg/dL, the dose should be increased by 2 units
-when it is >180 mg/dL, the dose should be increased by 6 units.
The use of which of the following medication classes has the potential for causing the greatest
reduction in A1c for a 45-year-old man with newly-diagnosed type 2 diabetes mellitus and a
current A1c of 10.5%?
SGLT2 inhibitor
Thiazolidinedione
DPP-4 inhibitor
Insulin formulation
- Correct Answer :Insulin formulation
A+ TEST BANK 1
, AANP Actual Exam
All other PO medications only reduce the A1C by 1-2%. For patients with >10% need to start with
insulin and reevaluate after several months.
Which of the following characteristics applies to type 2 diabetes mellitus?
a. Inactivity is a potent risk factor for the condition.
b. Genetic influences are associated with type 1 but not type 2 diabetes mellitus risk.
c. Exogenous insulin is consistently needed throughout the course of the disease.
d. "Pear-shaped" body habitus is often noted.
- Correct Answer :a. Inactivity is a potent risk factor for the condition.
diabetes mellitus is a complex metabolic disorder characterized by a variety of risk factors
including inactivity, obesity, genetics, medication, and aging.
You are teaching a 62-year-old patient with type 2 diabetes mellitus about using mealtime insulin
to help with the management of post-prandial hyperglycemia. You describe a situation where
blood sugar is between 200 and 250 mg/dL (11.1?13.9 mmol/L) and advise the appropriate dose
of rapid-acting insulin to attain a goal of <150 mg/dL (8.3 mmol/L) is:
1 unit.
2 units.
4 units.
8 units.
- Correct Answer :2 units.
One unit of rapid-acting insulin will result in a blood sugar decrease of approximately 50 mg/dL
(2.78 mmol/L). Therefore, in the example above, 2 units will be needed to attain the goal of <150
mg/dL.
Which of the following best describes the appropriate use of insulin lispro?
In an insulin pump
As a mealtime insulin
As a basal insulin
To prevent the Somogyi effect
A+ TEST BANK 2
, AANP Actual Exam
- Correct Answer :As a mealtime insulin
onset 15-30 minutes after administration and a peak of 30 minutes to 2.5 hours.
When prescribing glargine or detemir, the clinician should consider that:
-Its mechanism of action differs from that of other insulins.
-It is used as basal insulin.
-It reaches peak effect at 12 hours after injection.
-It can be mixed in the same syringe with rapid-acting insulin.
- Correct Answer :-It is used as basal insulin.
Using metformin in a 62-year-old person who has a 20-year history of T2DM and a GFR=28
mL/min/1.73 m2 can potentially increase the risk of:
QTc prolongation.
Renal failure.
Poor glycemic control.
Lactic acidosis
. - Correct Answer :Lactic acidosis.
ther risk factors for lactic acidosis with metformin use include concomitant use of certain
medications (e.g., topiramate),
-age 65 years and older
-having a radiological study with contrast, surgery and other procedures
hypoxic states (e.g., acute congestive heart failure)
excessive alcohol intake, and hepatic impairment.
The results of a radioactive iodine uptake scan of a 52-year-old woman with a thyroid mass
reveal a cold spot. This finding is most consistent with:
Amiodarone-induced thyroid disease.
Thyroid cyst.
Metabolically-active thyroid nodule.
Graves' disease
. - Correct Answer :Thyroid cyst.
Nonfunctional tissue does not uptake iodine, and on a radioactive iodine uptake scan a cyst will
appear as nonfunctional or "cold."
A+ TEST BANK 3
, AANP Actual Exam
Amiodarone-induced thyroid disease, active thyroid nodule, and Graves' disease are all
conditions of increased gland function, and nodules would scan as hyperfunctioning or "hot."
A 27-year-old woman is newly diagnosed with Graves' disease that will be treated with
methimazole or propylthiouracil. In counseling the patient, the NP mentions a potential risk for:
Renal dysfunction.
Weight gain.
Liver toxicity.
Peripheral neuropathy.
- Correct Answer :Liver toxicity.
Refer to endocrinology
Which of the following is most consistent with findings in thyroid cancer?
Hard, fixed thyroid mass of 2 cm in diameter
"Hot spot" on thyroid scan
Abnormally low TSH
Presence of TPO antibodies
- Correct Answer :Hard, fixed thyroid mass of 2 cm in diameter
A hard, fixed mass larger than 1-1.5 cm should raise suspicion of malignancy and be referred for
fine-needle aspiration biopsy.
Oral antimicrobials commonly used to treat H. pylori gastrointestinal tract infection include all of
the following except:
Metronidazole.
Vancomycin.
Clarithromycin.
Amoxicillin.
- Correct Answer :Vancomycin.
Amoxicillin and metronidazole are effective agents, and H. pylori resistance to these agents is
uncommon. Clarithromycin can also be used though resistance to this agent is increasing.
A+ TEST BANK 4
