➢ Updated 2 Version Exam + Study Guide
➢ True & False Questions
➢ Multiple Choice Questions and Answers
➢ Expert-Verified Explanations
Table of Contents
BIOD 331 MODULE 2 EXAM VERSION 1 ............................................ 1
BIOD 331 MODULE 2 EXAM VERSION 2 .......................................... 14
BIOD 331 MODULE 2 EXAM STUDY GUIDE .............................................. 27
BIOD 331 MODULE 2 EXAM VERSION 1
,1. Define neoplasia and neoplasm.
Answer:
Neoplasia refers to the process characterized by abnormal and uncontrolled cell
growth and differentiation, deviating from normal regulatory mechanisms. A
neoplasm, on the other hand, denotes the actual resultant mass or lesion of this
abnormal proliferation, commonly referred to as a "new growth" or tumor.
Verified Rationale:
Neoplasia involves alterations in the genetic and cellular pathways that normally
govern cellular replication and differentiation. The resultant neoplasm can be
benign (non-invasive and localized) or malignant (invasive and capable of
metastasis). The study of neoplasia is fundamental to understanding cancer
biology.
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2. Define proliferation and differentiation.
Answer:
Proliferation is the process of cell division leading to an increase in cell number,
crucial both for normal tissue growth and the replacement of lost cells.
Differentiation refers to the process by which unspecialized cells become
specialized in structure and function through changes in gene expression.
Verified Rationale:
, Cell proliferation enables tissue renewal and repair. Differentiation ensures that
cells acquire specific structures and functions necessary for the diverse activities
within tissues and organ systems. Pathologic disturbances in either proliferation or
differentiation are central to neoplastic disorders.
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3. Name and explain the three main groups of cells as categorized by
their proliferative activity.
Answer:
- Continuously dividing (or labile) cells: Examples include surface epithelial cells
(skin, gastrointestinal tract) and hematopoietic cells (blood).
- Quiescent (stable) cells: These cells, such as hepatocytes (liver) and kidney cells,
have a low level of replication but can proliferate in response to injury.
- Permanent (non-dividing) cells: Most neurons and cardiac muscle cells fall into
this category and have little to no capacity to divide postnatally.
Verified Rationale:
These categorizations reflect a tissue’s capacity for repair and regeneration. Labile
tissues can readily regenerate, stable tissues retain the ability to re-enter the cell
cycle if needed, whereas permanent tissues repair primarily by fibrosis.
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