Quiz 1 Pharmacology 5334 Questions
And Answers With Verified Solutions
100% Correct.
PCN drug-drug interactions - ANSWER -aminoglycosides
-bacteriostatic antibiotics
-probenecid
Cephalosporin Generation 1 - ANSWER -cephalexin
-cephazolin
-cephadoxil
Cephalosporin and PCN - ANSWER Cross allergy w/PCN
Carbapenems - ANSWER not active against MRSA
Vancomycin treats - ANSWER gram positive
Vancomycin AE - ANSWER ototoxicity, nephrotoxicity, red man syndrome
Vancomycin main danger - ANSWER Hosp/vent. pneumonia in pt w/ Crcl less than 50 as it
increases mortality
Monobactams treats - ANSWER gram negative aerobic
Fosfomycin treats - ANSWER enterococcus and Ecoli
Aminoglycosides treat - ANSWER gram negative bacilli
Aminoglycosides adverse effects - ANSWER ototoxicity and nephrotoxicity
aminoglycosides peak and trough - ANSWER Peak: 30 min after IV or IM
Trough: divided- before next dose, daily-1 hr before next dose (value should be low: like zero)
Sulfonamides MOA - ANSWER inhibit folic acid synthesis
UTI drugs - ANSWER 1) TMP/SMZ and nitrofurantoin
2) levofloxacin & ciprofloxacin
UTI in pregnancy - ANSWER TMP/SMZ, Cipro, Levo, augmentin, cephalexin
recurrent UTI prophylaxis - ANSWER TMP
Recurrent UTI other tx - ANSWER SMZ 3 x week for 6 months; TMP or nitro at bedtime for 6
mos.
Acute Bact Prostatitis Tx - ANSWER Floxacins
, Tetracycline adverse effects - ANSWER -Yellow/brown discoloration of teeth
-hepatotoxicity
-photosensitivity
-GI
-suprainfection/superinfection
tetracycline absorption is impaired by - ANSWER -magnesium laxative
-antacids
-Calcium
-iron sup.
-milk
tetracycline treats - ANSWER -lyme dx
-anthrax
-helicobacter pylori
-mycoplasma
Linezolid treats - ANSWER VRE and MRSA
Telithromycin BBW - ANSWER muscle weakness w/myasthenia gravis
Dalfopristin/Quinupristin BBW - ANSWER reserve only for infection when not responding to
vanco. to delay resistance
Chloramphenicol BBW - ANSWER fatal aplastic anemia
Retapamulin and mupirocin tx - ANSWER topical treatment for impetigo
Mupirocin (topical) - ANSWER MRSA in nostrils
TB treatment - ANSWER RIPE (rifampin, isoniazid, pyrazinamide, ethambutol); rifapentine
and rifabutin
TB treatment is effective when - ANSWER no mycobacteria in sputum and no colonies present
in culture
TB second line injection drugs - ANSWER Amikacin & Capreomycin
MDR-TB - ANSWER resistant to isoniazid and rifampin
XDR-TB - ANSWER resistant not only to isoniazid and rifampin but also to any
fluoroquinolone and at least one of inject. second line drugs
TB promoting resistance - ANSWER Daily observed therapy (DOT), intermittent dosing (2-3
times/week)
And Answers With Verified Solutions
100% Correct.
PCN drug-drug interactions - ANSWER -aminoglycosides
-bacteriostatic antibiotics
-probenecid
Cephalosporin Generation 1 - ANSWER -cephalexin
-cephazolin
-cephadoxil
Cephalosporin and PCN - ANSWER Cross allergy w/PCN
Carbapenems - ANSWER not active against MRSA
Vancomycin treats - ANSWER gram positive
Vancomycin AE - ANSWER ototoxicity, nephrotoxicity, red man syndrome
Vancomycin main danger - ANSWER Hosp/vent. pneumonia in pt w/ Crcl less than 50 as it
increases mortality
Monobactams treats - ANSWER gram negative aerobic
Fosfomycin treats - ANSWER enterococcus and Ecoli
Aminoglycosides treat - ANSWER gram negative bacilli
Aminoglycosides adverse effects - ANSWER ototoxicity and nephrotoxicity
aminoglycosides peak and trough - ANSWER Peak: 30 min after IV or IM
Trough: divided- before next dose, daily-1 hr before next dose (value should be low: like zero)
Sulfonamides MOA - ANSWER inhibit folic acid synthesis
UTI drugs - ANSWER 1) TMP/SMZ and nitrofurantoin
2) levofloxacin & ciprofloxacin
UTI in pregnancy - ANSWER TMP/SMZ, Cipro, Levo, augmentin, cephalexin
recurrent UTI prophylaxis - ANSWER TMP
Recurrent UTI other tx - ANSWER SMZ 3 x week for 6 months; TMP or nitro at bedtime for 6
mos.
Acute Bact Prostatitis Tx - ANSWER Floxacins
, Tetracycline adverse effects - ANSWER -Yellow/brown discoloration of teeth
-hepatotoxicity
-photosensitivity
-GI
-suprainfection/superinfection
tetracycline absorption is impaired by - ANSWER -magnesium laxative
-antacids
-Calcium
-iron sup.
-milk
tetracycline treats - ANSWER -lyme dx
-anthrax
-helicobacter pylori
-mycoplasma
Linezolid treats - ANSWER VRE and MRSA
Telithromycin BBW - ANSWER muscle weakness w/myasthenia gravis
Dalfopristin/Quinupristin BBW - ANSWER reserve only for infection when not responding to
vanco. to delay resistance
Chloramphenicol BBW - ANSWER fatal aplastic anemia
Retapamulin and mupirocin tx - ANSWER topical treatment for impetigo
Mupirocin (topical) - ANSWER MRSA in nostrils
TB treatment - ANSWER RIPE (rifampin, isoniazid, pyrazinamide, ethambutol); rifapentine
and rifabutin
TB treatment is effective when - ANSWER no mycobacteria in sputum and no colonies present
in culture
TB second line injection drugs - ANSWER Amikacin & Capreomycin
MDR-TB - ANSWER resistant to isoniazid and rifampin
XDR-TB - ANSWER resistant not only to isoniazid and rifampin but also to any
fluoroquinolone and at least one of inject. second line drugs
TB promoting resistance - ANSWER Daily observed therapy (DOT), intermittent dosing (2-3
times/week)
