NURS 5334 - Antimicrobial Recall Quiz
Questions And Answers With Verified Solutions
100% Correct.
Why do many medications lack pediatric dosing information in their drug labeling - ANSWER
There is lack of evidence-based literature on the safe and effective use of medications in children
Why are neonates at greater risk for toxicity with highly protein-bound drugs - ANSWER
Protein binding is decreased in neonates increasing the amount of free drug available
At what age are adult levels of renal function achieved - ANSWER 12 months
What is the most accurate device for measuring a 2.5mL dose for a child - ANSWER An oral
syringe
How do you help prevent medication errors - ANSWER Write out the term daily
In pediatric patients gastric acidity does not reach adult values for - ANSWER 2 years
Nalidixic acid may cause _______ in children - ANSWER cartilage erosion
Altered absorption of drugs in the elderly may result in _______ drug response - ANSWER
Delayed
You have an elderly patient taking warfarin. You add another protein binding drug. Which of the
following statements is correct? - ANSWER You will need to decrease dose of warfarin
In elderly, proper index of renal function is _____ - ANSWER Glomerular filtration rate (GFR)
List that identifies drugs with high likelihood of cause adverse effects in elderly - ANSWER
Beers list
Primary mechanism of antibacterial action of the penicillin's involve inhibition of - ANSWER
Cell wall synthesis by binding and inactivating penicillin binding proteins (PBPs)
Which statement about vancomycin is accurate - ANSWER Increases bacterial cell wall
permeability and inhibits RNA synthesis
The mechanism of action of the tetracyclines involves - ANSWER Inhibiting protein synthesis
Mechanism of action of aminoglycosides - ANSWER Causes misreading of the code on the
mRNA template to inhibit protein synthesis
Which statement is accurate regarding the antibacterial action of gentamicin - ANSWER
Gentamicin continues to exert antibacterial effects even after plasma level decrease below detectable
levels
If a patient was treated with the macrolide erythromycin, he/she should - ANSWER
Temporarily stop simvastatin while taking erythromycin
, 24 year old woman returned from vacation abroad suffering from traveler's diarrhea, and her problem has
not responded to antidiarrheal drugs. A pathogenic gram-negative bacillus is suspected. Which drug is
most likely to be effective in the treatment of this patient - ANSWER Ciprofloxacin
Which is accurate about fluoroquinolones - ANSWER Fluoroquinolones have different
therapeutic applications depending on the generation
Which adverse effect is MOST LIKELY to occur with sulfonamides - ANSWER Skin reactions
Which is true about ciprofloxacin - ANSWER During treatment, tendonitis and even tendon
rupture may occur
Primary reason for the use of drug combinations in treatment of TB is to - ANSWER Delay or
prevent emergence of resistance
Which is true about fluconazole - ANSWER Primary route of excretion is renal
55 year old man has been on anticoagulant treatment for many years and is newly diagnosed with TB.
Which of the following antimycobacterial agents would MOST LIKELY induce cytochrome P450
enzymes in the patient's liver thereby modifying the effects of his anticoagulant treatment -
ANSWER Rifampin
Which drug is an antiviral that can be used to decrease shedding with genital herpes - ANSWER
Valacyclovir
First generation cephalosporins are best against which organism - ANSWER Gram positive
cocci
Cefepime is eliminated via - ANSWER Tubular secretion and or glomerular filtration
Which cephalosporins cause bleeding tendencies - ANSWER cefotetan and ceftriaxone
Which cephalosporins induce alcohol intolerance - ANSWER Cefotetan and Cefazolin
Which macrolide is LEAST likely to cause QT prolongation - ANSWER Azithromycin
Which of the following cephalosporins has activity against gram negative anaerobic pathogens such as
Bacteroides Fragilis - ANSWER Cefoxitin [Mefoxin]
20 year comes in with UTI. Based on symptoms and UA, diagnosed with UTI. Cultures reveal
Enterococcus faecalis that is sensitive to all antibiotics usually tested for potential treatment. Which of the
following is an appropriate oral option to treat the UTI - ANSWER Amoxicillin
1st line antibiotic for patient with comorbidities [immunosuppression] who has pneumonia and can be
treated as an outpatient would be - ANSWER Levofloxacin
John is 4 week old infant who has been diagnosed with Chlamydial pneumonia. An appropriate treatment
for his pneumonia would be - ANSWER Erythromycin
Which is primary method of B-lactamase resistance with streptococcus pneumoniae - ANSWER
Modification of target site
Questions And Answers With Verified Solutions
100% Correct.
Why do many medications lack pediatric dosing information in their drug labeling - ANSWER
There is lack of evidence-based literature on the safe and effective use of medications in children
Why are neonates at greater risk for toxicity with highly protein-bound drugs - ANSWER
Protein binding is decreased in neonates increasing the amount of free drug available
At what age are adult levels of renal function achieved - ANSWER 12 months
What is the most accurate device for measuring a 2.5mL dose for a child - ANSWER An oral
syringe
How do you help prevent medication errors - ANSWER Write out the term daily
In pediatric patients gastric acidity does not reach adult values for - ANSWER 2 years
Nalidixic acid may cause _______ in children - ANSWER cartilage erosion
Altered absorption of drugs in the elderly may result in _______ drug response - ANSWER
Delayed
You have an elderly patient taking warfarin. You add another protein binding drug. Which of the
following statements is correct? - ANSWER You will need to decrease dose of warfarin
In elderly, proper index of renal function is _____ - ANSWER Glomerular filtration rate (GFR)
List that identifies drugs with high likelihood of cause adverse effects in elderly - ANSWER
Beers list
Primary mechanism of antibacterial action of the penicillin's involve inhibition of - ANSWER
Cell wall synthesis by binding and inactivating penicillin binding proteins (PBPs)
Which statement about vancomycin is accurate - ANSWER Increases bacterial cell wall
permeability and inhibits RNA synthesis
The mechanism of action of the tetracyclines involves - ANSWER Inhibiting protein synthesis
Mechanism of action of aminoglycosides - ANSWER Causes misreading of the code on the
mRNA template to inhibit protein synthesis
Which statement is accurate regarding the antibacterial action of gentamicin - ANSWER
Gentamicin continues to exert antibacterial effects even after plasma level decrease below detectable
levels
If a patient was treated with the macrolide erythromycin, he/she should - ANSWER
Temporarily stop simvastatin while taking erythromycin
, 24 year old woman returned from vacation abroad suffering from traveler's diarrhea, and her problem has
not responded to antidiarrheal drugs. A pathogenic gram-negative bacillus is suspected. Which drug is
most likely to be effective in the treatment of this patient - ANSWER Ciprofloxacin
Which is accurate about fluoroquinolones - ANSWER Fluoroquinolones have different
therapeutic applications depending on the generation
Which adverse effect is MOST LIKELY to occur with sulfonamides - ANSWER Skin reactions
Which is true about ciprofloxacin - ANSWER During treatment, tendonitis and even tendon
rupture may occur
Primary reason for the use of drug combinations in treatment of TB is to - ANSWER Delay or
prevent emergence of resistance
Which is true about fluconazole - ANSWER Primary route of excretion is renal
55 year old man has been on anticoagulant treatment for many years and is newly diagnosed with TB.
Which of the following antimycobacterial agents would MOST LIKELY induce cytochrome P450
enzymes in the patient's liver thereby modifying the effects of his anticoagulant treatment -
ANSWER Rifampin
Which drug is an antiviral that can be used to decrease shedding with genital herpes - ANSWER
Valacyclovir
First generation cephalosporins are best against which organism - ANSWER Gram positive
cocci
Cefepime is eliminated via - ANSWER Tubular secretion and or glomerular filtration
Which cephalosporins cause bleeding tendencies - ANSWER cefotetan and ceftriaxone
Which cephalosporins induce alcohol intolerance - ANSWER Cefotetan and Cefazolin
Which macrolide is LEAST likely to cause QT prolongation - ANSWER Azithromycin
Which of the following cephalosporins has activity against gram negative anaerobic pathogens such as
Bacteroides Fragilis - ANSWER Cefoxitin [Mefoxin]
20 year comes in with UTI. Based on symptoms and UA, diagnosed with UTI. Cultures reveal
Enterococcus faecalis that is sensitive to all antibiotics usually tested for potential treatment. Which of the
following is an appropriate oral option to treat the UTI - ANSWER Amoxicillin
1st line antibiotic for patient with comorbidities [immunosuppression] who has pneumonia and can be
treated as an outpatient would be - ANSWER Levofloxacin
John is 4 week old infant who has been diagnosed with Chlamydial pneumonia. An appropriate treatment
for his pneumonia would be - ANSWER Erythromycin
Which is primary method of B-lactamase resistance with streptococcus pneumoniae - ANSWER
Modification of target site
