Test Bank for Abrams’ Clinical Drug Therapy: Rationales for Nursing Practice, 13th Edition (Frandsen, 2025), Chapter 1-61 | All ChaptersTest Bank for Abrams’ Clinical Drug Therapy: Rationales for Nursing Practice, 13th Edition - Frandsen, 2025 - Chapter 1

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Material

Chapter 1, The Foundation of Pharmacology: Quality and Safety
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1. A woman diagnosed with obsessive–
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compulsive disorder has been prescribed oral paroxetine hydrochloride. What isss ss ss ss ss ss ss ss ss



the expected effect for this prescription?
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A. Curative effect on symptoms ss s s ss



B. Systemic effect on symptoms ss ss ss



C. Local effect on symptoms ss ss ss



D. Parenteral effect on symptoms ss ss ss




ANS: B s s s s



Rationale: Drugs that produce systemic effects are taken into the body, circulated
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throug h the bloodstream to their sites of action in various body tissues, and
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eventually eliminat ed from the body. Curative agents are given to cure a disease process. In
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this case, paro xetine hydrochloride will control the symptoms but not cure the disorder.
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Drugs with loca l effects, such as sunscreen and local anesthetics, act mainly at the site of
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application. Pa roxetine hydrochloride is not administered parenterally. Parenteral agents
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are administere d subcutaneously, intramuscularly, or intravenously.
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PTS: 1 REF: p. 3, Introduction OBJ: 1 ss s s



NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral
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Therapi es TOP: Chapter: 1: The Foundation of Pharmacology: Quality and
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Safety KEY: Integrated Process: Nursing Process
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BLM: Cognitive Level: Understand NOT: Multiple Choice
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2. A client has been prescribed an antibiotic. This medication is a naturally occurring
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substance that has been cheG
mRicAalDlyEm
SoBdOifOieSd.TW
.hCaOt Mi s another name for this type o
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f medication?
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A. Synthetic drug ss



B. Semisynthetic drug ss



C. Biotechnology drug ss



D. Prototype drug ss




ANS: B s s s s



Rationale: Semisynthetic drugs (e.g., many antibiotics) are naturally occurring substances
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that have been chemically modified. Synthetic drugs are more standardized in their chemi cal
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characteristics, more consistent in their effects, and less likely to produce allergic rea ctions.
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Biotechnology drugs involve manipulating DNA and RNA and recombining gene s into
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hybrid molecules that can be inserted into living organisms. Prototype drugs are th e first
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drug of a particular group to be developed.
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PTS: 1 REF: p. 3, Drug Sources OBJ: 1 ss ss ss



NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral
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Therapi es TOP: Chapter: 1: The Foundation of Pharmacology: Quality and
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Safety KEY: Integrated Process: Nursing Process
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BLM: Cognitive Level: Understand NOT: Multiple Choice
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3. Which classification applies to morphine? ss ss ss ss



A. Central nervous system depressant ss ss ss



B. Central nervous system stimulant ss ss ss

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Material

C. Anti-inflammatory
D. Antihypertensive
ANS: A s s s s



Rationale: Drugs are classified according to their effects on particular body systems,
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thei r therapeutic uses, and their chemical characteristics. Morphine is classified as a
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central nervous system depressant and will produce this effect in the client. A
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central nervous s ystem stimulant increases attention and raises mood. An anti-
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inflammatory agent decreases inflammation at the site of tissue or joint inflammation. An
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antihypertensive agent reduces blood pressure.
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PTS: 1 REF:
p. 3, Drug Classifications and Prototypes OBJ: 1 ss ss ss ss ss s s



NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral
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Therapi es TOP: Chapter: 1: The Foundation of Pharmacology: Quality and
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Safety KEY: Integrated Process: Nursing Process
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BLM: Cognitive Level: Remember s s NOT: Multiple Choice
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4. A client is administered amoxicillin. The generic name of this medication belongs to whi
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ch drug group?
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A. Selective serotonin reuptake inhibitors ss ss ss



B. Diuretics
C. Penicillins
D. ACE inhibitors ss




ANS: C s s s s



Rationale: The generic n a mGeR oAfD
t eEn Si nBdOicOa tSe T
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t hCe Od r u g group (e.g., drugs with generic
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na mes ending in ―cillin‖ are penicillins). Selective serotonin reuptake inhibitors are
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medicat
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ions that have antidepressant effects; SSRI is a broad classification, not a generic name. D
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iuretics are medications that increase urine output; diuretic is a broad classification, not a
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generic name. ACE inhibitor is the broad classification for the angiotensin receptor block ers,
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not the generic name.
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PTS: 1 REF: p. 3, Drug Names OBJ: 2 ss ss ss



NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral
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Therapi es TOP: Chapter: 1: The Foundation of Pharmacology: Quality and
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Safety KEY: Integrated Process: Nursing Process
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BLM: Cognitive Level: Understand s s NOT: Multiple Choice
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5. The administration of diphenhydramine is regulated by which U.S. government agency?
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A. Public Health Service ss ss



B. Federal Trade Commission ss ss



C. Occupational Safety and Health Administration ss ss ss ss



D. Food and Drug ss s s




ss Administration ANS: ss D

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Material


Rationale: The Food and Drug Administration approves drugs for over-the-
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counter availability, including the transfer of drugs from prescription to OTC status, and
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may require clinical trials to determine the safety and effectiveness of OTC use. The P ublic
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Health Service is regulated by the state to maintain the health of individual
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citizen s of the state. The Federal Trade Commission regulates imports and exports
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throughout t he nation. The Occupational Safety and Health Administration regulates
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safety within the workplace.
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PTS: 1 REF:
p. 4, Prescription and Nonprescription Drugs OBJ:4
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NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral
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Therapi es TOP: Chapter: 1: The Foundation of Pharmacology: Quality and
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Safety KEY: Integrated Process: Nursing Process
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BLM: Cognitive Level: Understand
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6. In ss the U.S., the administration of anabolic steroids is regulated by which law?
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A. The Food, Drug, and Cosmetic Act of 1938
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B. The Comprehensive Drug Abuse Prevention and Control Act
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C. The Harrison Narcotic Act
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D. The Sherley Amendment ss ss




ANS: B s s s s



Rationale: The Comprehensive Drug Abuse Prevention and Control Act regulates the ma
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nufacture and distribution of narcotics, stimulants, depressants, hallucinogens, and anabol
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ic steroids. The Food, Drug, and Cosmetic Act of 1938 revised and broadened FDA
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pow ers and responsibilities, giving the FDA control over drug safety. The Harrison
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Narcotic Act restricted the importation, manufacture, sale, and use of opium, cocaine,
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marijuana, a
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nd other drugs that the act de f i Gn eRd AaDs E
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tiO
csSTh.eCSOhM
.T erley Amendment of 1912 prohib
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ited fraudulent claims of drug effectiveness.
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PTS: 1 REF:
p. 4, Prescription and Nonprescription Drugs OBJ:3
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NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral
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Therapi es TOP: Chapter: 1: The Foundation of Pharmacology: Quality and
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Safety KEY: Integrated Process: Nursing Process
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BLM: Cognitive Level: Remember
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7. A nurse is responsible for maintaining an accurate count and record of the controlled
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substances on the nursing division. This nursing action is regulated by which U.S. law or
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agency?
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A. The Food, Drug, and Cosmetic Act of 1938
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B. The Public Health Service ss ss ss



C. The Drug Enforcement Administration ss ss s s



D. The Sherley ss




ss Amendment ANS: ss




s s C