Advanced Pharmacology Midterm (Chemotherapy Drugs) |
Exam Practice Questions & Verified Answers | 2025/2026
Updated Study Guide
A 24-Year-Old Pregnant Woman Presents To The Urgent Care Clinic With Fever And Urinary Frequency
And Urgency. She Is Diagnosed With A Urinary Tract Infection (UTI). Based On Potential Harm To The
Fetus, Which Of The Following Medications Should Be Avoided In Treating Her UTI?
A. Nitrofuratoin
B. Amoxicillin
C. Cephalexin
D. Doxycycline
ANSWER: D. Doxycycline
Pregnancy Category D, Associated With Hepatotoxicity In Mothers, Can Cause Decreased Bone And
Teeth Development In Infants And Impair Fetal Long Bone Growth.
Which Of The Following Is The Primary Method Of B~-Lactam Resistance With Streptococcus
Pneumoniae?
A. Modification Of Target Site
B. Decreased Drug Levels Due To Changes In Permeability
C. Decreased Drug Levels Due To An Efflux Pump
D. Enzymatic Inactivation
ANSWER: A. Modification Of Target-
ß-Lactam Resistance Involves Alteration And Restructuring In One Or More Of The Major Penicillin
Binding Proteins.
Which Of The Following Agents Is Considered A Narrow Spectrum Antibiotic?
A. Ceftriaxone
, B. Ciprofloxacin
C. Isoniazid
D. Lmipenem
ANSWER: C. Isoniazid
Isoniazid Is Only Active Against Mycobacterium Tuberculosis, While Ceftriaxone, Ciprofloxacin, And
Imipenem Are Considered Broad Spectr~M Due To Their Activity Against Multiple Types Of Bacteria And
1ncreased Risk For Contributing To The Development Of A Superinfection.
Which Of The Following Antibiotics Exhibits Concentration- Dependent Killing?
A. Clindarnycin
B. Linezolid
C. Vancomycin
D. Daptomycin
ANSWER: D. Daptomycin
Clindamycin, Linezolid, And Vancomycin Exhibit Time-Dependent Killing, While Daptomycin Works Best
When Administered In A Fashion That Optimizes Concentration- Dependent Killing.
Which Of The Following Antibiotics Exhibits A Long Post Antibiotic Effect That Permits Once-Daily
Dosing?
A. Gentamicin
B. Penicillin G
C. Vancomycin
D. Aztreonam
ANSWER: A. Gentamicin
Exam Practice Questions & Verified Answers | 2025/2026
Updated Study Guide
A 24-Year-Old Pregnant Woman Presents To The Urgent Care Clinic With Fever And Urinary Frequency
And Urgency. She Is Diagnosed With A Urinary Tract Infection (UTI). Based On Potential Harm To The
Fetus, Which Of The Following Medications Should Be Avoided In Treating Her UTI?
A. Nitrofuratoin
B. Amoxicillin
C. Cephalexin
D. Doxycycline
ANSWER: D. Doxycycline
Pregnancy Category D, Associated With Hepatotoxicity In Mothers, Can Cause Decreased Bone And
Teeth Development In Infants And Impair Fetal Long Bone Growth.
Which Of The Following Is The Primary Method Of B~-Lactam Resistance With Streptococcus
Pneumoniae?
A. Modification Of Target Site
B. Decreased Drug Levels Due To Changes In Permeability
C. Decreased Drug Levels Due To An Efflux Pump
D. Enzymatic Inactivation
ANSWER: A. Modification Of Target-
ß-Lactam Resistance Involves Alteration And Restructuring In One Or More Of The Major Penicillin
Binding Proteins.
Which Of The Following Agents Is Considered A Narrow Spectrum Antibiotic?
A. Ceftriaxone
, B. Ciprofloxacin
C. Isoniazid
D. Lmipenem
ANSWER: C. Isoniazid
Isoniazid Is Only Active Against Mycobacterium Tuberculosis, While Ceftriaxone, Ciprofloxacin, And
Imipenem Are Considered Broad Spectr~M Due To Their Activity Against Multiple Types Of Bacteria And
1ncreased Risk For Contributing To The Development Of A Superinfection.
Which Of The Following Antibiotics Exhibits Concentration- Dependent Killing?
A. Clindarnycin
B. Linezolid
C. Vancomycin
D. Daptomycin
ANSWER: D. Daptomycin
Clindamycin, Linezolid, And Vancomycin Exhibit Time-Dependent Killing, While Daptomycin Works Best
When Administered In A Fashion That Optimizes Concentration- Dependent Killing.
Which Of The Following Antibiotics Exhibits A Long Post Antibiotic Effect That Permits Once-Daily
Dosing?
A. Gentamicin
B. Penicillin G
C. Vancomycin
D. Aztreonam
ANSWER: A. Gentamicin
