With Complete Solutions
_____________ inhibits an enzyme that breaks down
_____________. Correct Answers Cilastatin; imipenem
*Aminoglycosides* Correct Answers
*Carbapenems* Correct Answers
*Cephalosporins* Correct Answers
*End of Beta-Lactam Antibiotics* Correct Answers
*Macrolides* Correct Answers
*Monobactams* Correct Answers
*Nitrofuran* Correct Answers
*Nitroimidazole* Correct Answers
*Oxazolidinones* Correct Answers
*Penicillins* Correct Answers
*Quinolones* Correct Answers
*Tetracyclines* Correct Answers
All Carbapenems are given.. Correct Answers Parenterally
,*so only used at hospitals
Also consider that ____________ is delayed with food BUT GI
upset is decreased. Correct Answers Absorption
*therefore many Macrolides are taken after meals or snacks to
help decrease N/V but may still also require anti-nausea meds
Aminoglycosides are poorly absorbed through the GI tract and
therefore are given... Correct Answers Parenterally
Aminoglycosides are very __________ antibiotics with serious
toxicities. Correct Answers Potent
*reserved only for serious and life threatening infections
Aminoglycosides have poor ______ absorption and therefore are
only given in ____ or ____ form. Correct Answers Oral; IV or
IM
Aminoglycosides mostly kill G (-/+) bacteria. Correct Answers
G-
*and some G+
Antibiotics also have 2 different ranges in which they will kill
bacteria. What are they? Correct Answers 1. Broad Spectrum:
covers wide area/range of bacteria
2. Narrow Spectrum: specific target; typically less risks and SE
, Antibiotics have to differ actions in which they treat bacteria.
What are they? Correct Answers 1. Bactericidal: kills bacteria
directly
2. Bacteriostatic: inhibits growth of bacteria killing them
indirectly (d/t lack of ability to replicate)
Are aminoglycosides bactericidal or bacteriostatic? Correct
Answers bactericidal
Are Cephalosporins bactericidal or Bacteriostatic? Correct
Answers Bactericidal
Are Cephalosporins Broad or Narrow spectrum? Correct
Answers Broad
Are Penicillins broad or narrow spectrum antibiotics? Correct
Answers Broad
*they kill a wide variety of bacteria
Are quinolones broad or narrow spectrum? Correct Answers
Broad
Aztreonam (Azactam) is a *synthetic* ______-__________
antibiotic. Correct Answers Beta-lactate
Aztreonam (Azactam) is given primarily against active aerobic
G (-/+) bacteria. Correct Answers G-
Aztreonam (Azactam) is given via ______________ only.
Correct Answers Parenteral