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1. What is immunohematology?: is the study of immune basis of hematology
2. what are Antigens: A substance recognized by the body as being foreign
able to stimulate an immune response they can be found in carbohydrates ,
proteins and lipides
proteins of marketer found on the surface of red blood cells ( RBC ) these
determine your blood types ( like A , B RH
3. what are Antibodies: Antibody a protein substance secreted by plasm cells
that is developed in. response to ( and interacting specifically with) and antigen
we will deal mostly with IgM and IgG
4. Agglutination: clumping of red blood cells when antibodies bind to their
matching antigens
5. what is hemolysis: are the destruction or bursting of red blood cells , ofter
due to an immune reaction
,Example
if some is giving the wrong blood
6. there are how many major blood group system: they are 9
but 47 in total
7. what is the primary reason we transfuse blood?: because of Anemia
8. what are some other reason we transude blood: to support Hematological
condition sickie cells disease Beta thalassemia diamond Blacktan anemia
Aplastic anemia
Hemophilia
Bleeding /traumatic events
9. what do red blood produce: Bleeding and Anemia
10. Platelets: platelet related disorders and clotting problem,
11. Fresh frozen plasma and cryoprecipitate: coagulation disorders and clotting
problem
12. what do we need to take in to considration doing blood transfusion: we
need to know
the different blood types like A , B , AB, and O
what the patient need and
, what risk Vs the benefits of transfusion
13. what do we also need to consideration for Blood transfusion: we need to
considerations RBC life cycle like ATP which is energy that is used in our
metablase.
90 % is due in the process of Glycolysis, and 2 ATP in the process
14. what is Spectrin: is there to ensures cells member is permeable by anions
and water, and impermeable by cation. and still flexible
except though specify PUMPS when
moved by cation
pumps sodium out of RBC, potassium into RBC
15. 2 ATP
Glucose Add phosphate from ATP: Glucose-6 phosphate
16. fructose-6-phosphate add another phosphate from ATP: fructose-1,6-
bisphosphate
17. G3P: WILL GIVE US 1-3 Biophsophglycersate
18. Net ATP: 2
19. NADH made: 2