Complement - correct answer30 serum proteins that have enzymatic activity and are heat labile;
measurable
Hemolysin - correct answer An antibody that activates complement, leading to lysis of Red Blood Cells
(RBCs)
Adjuvant - correct answer couple with certain immunogens to heighten response.
Affinity - correct answer initial force of attraction between one antigen and one antibody. How attracted
they are to each other.
Antigenicity - correct answer The ability of a foreign substance to bind to the receptors involved in or
produced during the immune response (e.g., antibodies)
Avidity - correct answer the measure of the overall strength of the binding of the antigen with many
antigenic determinants and multivalent antibodies.
Epitope - correct answer chemical groups on antigens that the antibodies bind to.
Hapten - correct answer small molecules that are antigenic but too small to elicit an immune response.
Immunogen - correct answer ra substance that is capable of eliciting an immune response
Immunogenicity - correct answer the ability of a molecule to elicit an immune response. Depends on
composition, size, etc.
Primary vs. Secondary humoral response - correct answer primary - main antibody IgM; lower antibody
affinity; long lag time
, secondary - main antibody IgG; less antigen needed to stimulate response
Sequence of events in a normal immune response - correct answer1. antigen recognition
2. activation
3. antigen elimination
4. homeostasis
5. memory
Spleen:
primary or secondary?
what does it do? - correct answer Secondary; major site for trapping blood-borne pathogens
Lymph nodes:
primary or secondary?
what do they do? - correct answer Secondary; sites of interaction during initial stages of the immune
response. Packed with B and T cells and dendritic cells
MHC class I:
structure, what type of cell it is present on, what it presents - correct answer structure: 3 alpha chains
and 1 beta
presented on: nucleated cells
presents: viral proteins
endogenous; interacts with CD8+
MHC class II:
structure, what type of cell it is present on, what it presents - correct answer structure: 2 alpha 2 beta
present on: B cells and antigen presenting cells