MMSC409 EXAM 1 2025 QUESTIONS AND
ANSWERS
Where are antigens found - ANS RBC membrane
Where is antibody found - ANS serum/plasma
What is the clumping together of RBC or any particulate matter resulting from interaction of
antibody and its corresponding antigen - ANS agglutination
What is the disruption of the RBC membrane and the subsequent release of hemoglobin into
the suspending medium or plasma - ANS hemolysis
ATP maintains levels of ___________, which helps maintain the shape of RBC so the cells can
move throughout the bloodstream - ANS spectrin
Hemoglobin has 4 chains: 2 _________ chains and 2 _______ chains - ANS alpha, beta
The function of this molecule is to carry oxygen from the lungs to the tissues -
ANS Hemoglobin
A shift to the left results in increased/decreased temp? - ANS Decreased
1 @COPYRIGHT THEBRIGHT 2025/2026
,A shift to the left results in increased/decreased 2,3 DPG? - ANS Decreased
A shift to the left results in increased/decreased pH? - ANS Increased
A shift to the right results in increased/decreased DPG? - ANS increased
A shift to the right results in increased/decreased temperature? - ANS Increased
A shift to the right results in increased/decreased temp? - ANS Decreased
This molecule controls hemoglobin affinity for oxygen - ANS 2,3 DPG
This anticoagulant functions by binding calcium - ANS Sodium citrate
What does monobasic sodium phosphate buffer do - ANS Maintains a 7 pH
What does dextrose do - ANS Feeds RBC
Adenine extends shelf life to __ days - ANS 35
What are ACD-A,CPR,CP2D - ANS Anticoagulants
What is the shelf life of an anticoagulant - ANS 21 days
What do anticoagulants contain - ANS Sodium citrate
Monobasic sodium phosphate
2 @COPYRIGHT THEBRIGHT 2025/2026
, Dextrose
This is an additional nutrient that is added after the whole blood is separated and extends the
shelf life of the blood - ANS Additive
What are examples of additives and what do they contain - ANS AS-1,3,5
Saline
Adenine
Glucose
What is a loss of viability and function associated with certain biochemical changes that are
initiated when blood is stored in vitro - ANS Storage lesion
What increases in RBC storage lesion - ANS lactic acid
How does storage lesion affect the oxygen dissociation curve - ANS Shift to the left
What are the correct ranges for temp,pulse,bp and hemoglobin/hematocrit values for blood
donation - ANS <37.5 degrees celsius
50-100bpm
<180/<100
Females >12.5g/dL
Males >13.0 g/dL
3 @COPYRIGHT THEBRIGHT 2025/2026
ANSWERS
Where are antigens found - ANS RBC membrane
Where is antibody found - ANS serum/plasma
What is the clumping together of RBC or any particulate matter resulting from interaction of
antibody and its corresponding antigen - ANS agglutination
What is the disruption of the RBC membrane and the subsequent release of hemoglobin into
the suspending medium or plasma - ANS hemolysis
ATP maintains levels of ___________, which helps maintain the shape of RBC so the cells can
move throughout the bloodstream - ANS spectrin
Hemoglobin has 4 chains: 2 _________ chains and 2 _______ chains - ANS alpha, beta
The function of this molecule is to carry oxygen from the lungs to the tissues -
ANS Hemoglobin
A shift to the left results in increased/decreased temp? - ANS Decreased
1 @COPYRIGHT THEBRIGHT 2025/2026
,A shift to the left results in increased/decreased 2,3 DPG? - ANS Decreased
A shift to the left results in increased/decreased pH? - ANS Increased
A shift to the right results in increased/decreased DPG? - ANS increased
A shift to the right results in increased/decreased temperature? - ANS Increased
A shift to the right results in increased/decreased temp? - ANS Decreased
This molecule controls hemoglobin affinity for oxygen - ANS 2,3 DPG
This anticoagulant functions by binding calcium - ANS Sodium citrate
What does monobasic sodium phosphate buffer do - ANS Maintains a 7 pH
What does dextrose do - ANS Feeds RBC
Adenine extends shelf life to __ days - ANS 35
What are ACD-A,CPR,CP2D - ANS Anticoagulants
What is the shelf life of an anticoagulant - ANS 21 days
What do anticoagulants contain - ANS Sodium citrate
Monobasic sodium phosphate
2 @COPYRIGHT THEBRIGHT 2025/2026
, Dextrose
This is an additional nutrient that is added after the whole blood is separated and extends the
shelf life of the blood - ANS Additive
What are examples of additives and what do they contain - ANS AS-1,3,5
Saline
Adenine
Glucose
What is a loss of viability and function associated with certain biochemical changes that are
initiated when blood is stored in vitro - ANS Storage lesion
What increases in RBC storage lesion - ANS lactic acid
How does storage lesion affect the oxygen dissociation curve - ANS Shift to the left
What are the correct ranges for temp,pulse,bp and hemoglobin/hematocrit values for blood
donation - ANS <37.5 degrees celsius
50-100bpm
<180/<100
Females >12.5g/dL
Males >13.0 g/dL
3 @COPYRIGHT THEBRIGHT 2025/2026
