NEWEST ASCP EXAM STUDY GUIDE WITH
COMPLETE QUESTIONS AND CORRECT
ANSWERS GRADED A+
Where is the main site of action for monocytes after diapedesis?
Correct Answer Body tissues
Methylene blue stain works by: Correct Answer Staining cellular
components that have an acidic pH such as ribosomes, DNA, and
RNA
Which white blood cell population would have the MOST side
scatter when analyzed using flow cytometry? Correct Answer
Granulocytes
All of the following methods are used in the diagnosis and
classification of acute leukemia, EXCEPT? Correct Answer
Reticulocyte count
Complaints of pain from a patient with sickle cell disease are most
likely associated with which of the following conditions/events?
Correct Answer Vaso-occlusive crisis
,Which of the following is a valid reason for evaluating red cell
morphology as part of the differential procedure? Correct Answer
May provide diagnostic information to the physician.
All of the following tests are useful in the diagnosis of heparin
induced thrombocytopenia (HIT) EXCEPT: Correct Answer Dilute
partial thromboplastin time (DTT)
The INR (international normalized ratio) is calculated using the
following formula: Correct Answer INR=(PT patient / PT normal)
raised to the ISI.
A 2-year-old girl, who had been treated with upper respiratory
tract infection a few weeks ago, showed multiple bruises and had
the following laboratory Findings:
Hgb=13.5 g/dL
RBC= 3.9•10^12/L
WBC=8.0 • 10^9/L
Platelets= 5•10^9/L
Bone Marrow M:E ratio= 3:1
megakaryocytes= increased
these results are most suggestive of which condition? Correct
Answer Immune (idiopathic) thrombocytopenic purpura
,Why is hereditary hemochromatosis (HH) thought to be
underdiagnosed? Correct Answer Its early symptoms are
nonspecific and vague, and generally do not get serious until later
in life.
Which of the following is an important technique consideration in
order to obtain consistently high quality bone marrow smears?
Correct Answer Select or concentrate bone marrow spicules,
ensuring they are transferred to the slide.
Which of the following red cell inclusions are often found in
peripheral blood smears of patients with sideroblastic anemia?
Correct Answer Pappenheimer bodies
A peripheral blood smear with many myeloid cells was presented
for morphology review (see image on the
right). Toxic granulation and vacuoles in the neutrophil most likely
represent which of the following conditions? Correct Answer
Septicemia
The cells which release von Willebrand's Factor (vWF) are:
Correct Answer Platelets and endothelial cells
An increased reticulocyte count MAY be found in all of the
following conditions, EXCEPT? Correct Answer Aplastic anemia
, Which of the following assays is commonly used to confirm the
diagnosis of Activated Protein C resistance? Correct Answer
Factor V Leiden Mutation Assay
Ristocetin is used in certain von Willebrand Factor (VWF)
functional assays. The reason it is used is because: Correct
Answer Ristocetin enhances binding of vWF to platelet GPIb.
All of the cells listed below function as a phagocyte, EXCEPT?
Correct Answer Eosinophils
Which of the following may result in a platelet count of 230.0 X
10°/L with a bleeding time of 15 minutes. Correct Answer
Defective platelet function
Abnormal platelet function seen in patients with Bernard-Soulier
Syndrome is caused by which of the following platelet
components? Correct Answer Defective glycoprotein Ib/IX
Which of the following factors is known as Hageman factor?
Correct Answer Factor XII
X =Stuart factor
V = proaccelerin
VII = proconvertin or stable factor
COMPLETE QUESTIONS AND CORRECT
ANSWERS GRADED A+
Where is the main site of action for monocytes after diapedesis?
Correct Answer Body tissues
Methylene blue stain works by: Correct Answer Staining cellular
components that have an acidic pH such as ribosomes, DNA, and
RNA
Which white blood cell population would have the MOST side
scatter when analyzed using flow cytometry? Correct Answer
Granulocytes
All of the following methods are used in the diagnosis and
classification of acute leukemia, EXCEPT? Correct Answer
Reticulocyte count
Complaints of pain from a patient with sickle cell disease are most
likely associated with which of the following conditions/events?
Correct Answer Vaso-occlusive crisis
,Which of the following is a valid reason for evaluating red cell
morphology as part of the differential procedure? Correct Answer
May provide diagnostic information to the physician.
All of the following tests are useful in the diagnosis of heparin
induced thrombocytopenia (HIT) EXCEPT: Correct Answer Dilute
partial thromboplastin time (DTT)
The INR (international normalized ratio) is calculated using the
following formula: Correct Answer INR=(PT patient / PT normal)
raised to the ISI.
A 2-year-old girl, who had been treated with upper respiratory
tract infection a few weeks ago, showed multiple bruises and had
the following laboratory Findings:
Hgb=13.5 g/dL
RBC= 3.9•10^12/L
WBC=8.0 • 10^9/L
Platelets= 5•10^9/L
Bone Marrow M:E ratio= 3:1
megakaryocytes= increased
these results are most suggestive of which condition? Correct
Answer Immune (idiopathic) thrombocytopenic purpura
,Why is hereditary hemochromatosis (HH) thought to be
underdiagnosed? Correct Answer Its early symptoms are
nonspecific and vague, and generally do not get serious until later
in life.
Which of the following is an important technique consideration in
order to obtain consistently high quality bone marrow smears?
Correct Answer Select or concentrate bone marrow spicules,
ensuring they are transferred to the slide.
Which of the following red cell inclusions are often found in
peripheral blood smears of patients with sideroblastic anemia?
Correct Answer Pappenheimer bodies
A peripheral blood smear with many myeloid cells was presented
for morphology review (see image on the
right). Toxic granulation and vacuoles in the neutrophil most likely
represent which of the following conditions? Correct Answer
Septicemia
The cells which release von Willebrand's Factor (vWF) are:
Correct Answer Platelets and endothelial cells
An increased reticulocyte count MAY be found in all of the
following conditions, EXCEPT? Correct Answer Aplastic anemia
, Which of the following assays is commonly used to confirm the
diagnosis of Activated Protein C resistance? Correct Answer
Factor V Leiden Mutation Assay
Ristocetin is used in certain von Willebrand Factor (VWF)
functional assays. The reason it is used is because: Correct
Answer Ristocetin enhances binding of vWF to platelet GPIb.
All of the cells listed below function as a phagocyte, EXCEPT?
Correct Answer Eosinophils
Which of the following may result in a platelet count of 230.0 X
10°/L with a bleeding time of 15 minutes. Correct Answer
Defective platelet function
Abnormal platelet function seen in patients with Bernard-Soulier
Syndrome is caused by which of the following platelet
components? Correct Answer Defective glycoprotein Ib/IX
Which of the following factors is known as Hageman factor?
Correct Answer Factor XII
X =Stuart factor
V = proaccelerin
VII = proconvertin or stable factor
