1
2025 ATI RN Pharmacology Proctored
Retake Exam – 80 Authentic NGN
Questions with 100% Verified Answers &
Detailed Rationales | A+ Graded
Student Name: _________________________
Date: _______________
Time Limit: 90 minutes
Total Questions: 75
Instructions
• This exam contains 75 multiple-choice questions covering drug classifications, side
effects, contraindications, and patient education.
• Read each question carefully and select the best answer.
• Ensure all answers are marked clearly.
• A score of 75% or higher is recommended for ATI RN Pharmacology success.
• No external resources are permitted unless specified.
Drug Classifications
1. MCQ: A nurse is preparing to administer a medication to a patient with hypertension.
Which drug belongs to the angiotensin-converting enzyme (ACE) inhibitor class?
a. Amlodipine
b. Lisinopril
c. Metoprolol
d. Hydrochlorothiazide
Rationale: Lisinopril (b) is an ACE inhibitor that reduces blood pressure by inhibiting
angiotensin II formation. Amlodipine (a) is a calcium channel blocker, metoprolol (c) is a
beta-blocker, and hydrochlorothiazide (d) is a thiazide diuretic, per ATI 2025
pharmacology guidelines.
2. MCQ: A patient with type 2 diabetes is prescribed a medication to improve insulin
sensitivity. Which drug is classified as a biguanide?
a. Insulin glargine
b. Metformin
c. Glipizide
d. Pioglitazone
, 2
Rationale: Metformin (b) is a biguanide that decreases hepatic glucose production and
improves insulin sensitivity. Insulin glargine (a) is a long-acting insulin, glipizide (c) is a
sulfonylurea, and pioglitazone (d) is a thiazolidinedione, per ATI standards.
3. MCQ: A nurse is administering an anticoagulant to a patient with atrial fibrillation.
Which medication is a direct thrombin inhibitor?
a. Warfarin
b. Dabigatran
c. Heparin
d. Clopidogrel
Rationale: Dabigatran (b) directly inhibits thrombin, preventing clot formation. Warfarin
(a) is a vitamin K antagonist, heparin (c) enhances antithrombin, and clopidogrel (d) is an
antiplatelet, per ATI 2025 guidelines.
4. MCQ: A patient with depression is prescribed a medication. Which drug is a selective
serotonin reuptake inhibitor (SSRI)?
a. Amitriptyline
b. Sertraline
c. Bupropion
d. Phenelzine
Rationale: Sertraline (b) is an SSRI that increases serotonin levels. Amitriptyline (a) is a
tricyclic antidepressant, bupropion (c) is an NDRI, and phenelzine (d) is an MAOI, per
ATI standards.
5. MCQ: A nurse is preparing to administer a bronchodilator for asthma. Which medication
is a short-acting beta-2 agonist (SABA)?
a. Ipratropium
b. Albuterol
c. Fluticasone
d. Montelukast
Rationale: Albuterol (b) is a SABA used for acute asthma relief. Ipratropium (a) is an
anticholinergic, fluticasone (c) is a corticosteroid, and montelukast (d) is a leukotriene
modifier, per ATI guidelines.
6. MCQ: A patient with heart failure is prescribed a loop diuretic. Which medication
belongs to this class?
a. Spironolactone
b. Furosemide
c. Hydrochlorothiazide
d. Mannitol
Rationale: Furosemide (b) is a loop diuretic that promotes fluid excretion. Spironolactone
(a) is a potassium-sparing diuretic, hydrochlorothiazide (c) is a thiazide diuretic, and
mannitol (d) is an osmotic diuretic, per ATI 2025 standards.
7. MCQ: A nurse is administering an antibiotic for a bacterial infection. Which drug is a
penicillin?
a. Azithromycin
b. Amoxicillin
c. Ciprofloxacin
d. Doxycycline
Rationale: Amoxicillin (b) is a penicillin antibiotic. Azithromycin (a) is a macrolide,
, 3
ciprofloxacin (c) is a fluoroquinolone, and doxycycline (d) is a tetracycline, per ATI
guidelines.
8. MCQ: A patient with seizures is prescribed an anticonvulsant. Which medication is a
sodium channel blocker?
a. Levetiracetam
b. Carbamazepine
c. Valproate
d. Gabapentin
Rationale: Carbamazepine (b) blocks sodium channels to prevent seizures. Levetiracetam
(a), valproate (c), and gabapentin (d) have different mechanisms, per ATI 2025 standards.
9. MCQ: A nurse is preparing to administer a medication for hyperthyroidism. Which drug
is an antithyroid medication?
a. Levothyroxine
b. Methimazole
c. Liothyronine
d. Propranolol
Rationale: Methimazole (b) inhibits thyroid hormone synthesis. Levothyroxine (a) and
liothyronine (c) are thyroid replacements, and propranolol (d) is a beta-blocker, per ATI
guidelines.
10. MCQ: A patient with chronic pain is prescribed an opioid analgesic. Which medication
belongs to this class?
a. Ibuprofen
b. Morphine
c. Acetaminophen
d. Aspirin
Rationale: Morphine (b) is an opioid analgesic. Ibuprofen (a) and aspirin (d) are NSAIDs,
and acetaminophen (c) is a non-opioid analgesic, per ATI standards.
11. MCQ: A nurse is administering a medication for gout. Which drug is a xanthine oxidase
inhibitor?
a. Colchicine
b. Allopurinol
c. Probenecid
d. Indomethacin
Rationale: Allopurinol (b) reduces uric acid production. Colchicine (a) reduces
inflammation, probenecid (c) increases uric acid excretion, and indomethacin (d) is an
NSAID, per ATI 2025 guidelines.
12. MCQ: A patient with bipolar disorder is prescribed a mood stabilizer. Which drug
belongs to this class?
a. Fluoxetine
b. Lithium
c. Lorazepam
d. Risperidone
Rationale: Lithium (b) is a mood stabilizer for bipolar disorder. Fluoxetine (a) is an SSRI,
lorazepam (c) is a benzodiazepine, and risperidone (d) is an antipsychotic, per ATI
standards.
2025 ATI RN Pharmacology Proctored
Retake Exam – 80 Authentic NGN
Questions with 100% Verified Answers &
Detailed Rationales | A+ Graded
Student Name: _________________________
Date: _______________
Time Limit: 90 minutes
Total Questions: 75
Instructions
• This exam contains 75 multiple-choice questions covering drug classifications, side
effects, contraindications, and patient education.
• Read each question carefully and select the best answer.
• Ensure all answers are marked clearly.
• A score of 75% or higher is recommended for ATI RN Pharmacology success.
• No external resources are permitted unless specified.
Drug Classifications
1. MCQ: A nurse is preparing to administer a medication to a patient with hypertension.
Which drug belongs to the angiotensin-converting enzyme (ACE) inhibitor class?
a. Amlodipine
b. Lisinopril
c. Metoprolol
d. Hydrochlorothiazide
Rationale: Lisinopril (b) is an ACE inhibitor that reduces blood pressure by inhibiting
angiotensin II formation. Amlodipine (a) is a calcium channel blocker, metoprolol (c) is a
beta-blocker, and hydrochlorothiazide (d) is a thiazide diuretic, per ATI 2025
pharmacology guidelines.
2. MCQ: A patient with type 2 diabetes is prescribed a medication to improve insulin
sensitivity. Which drug is classified as a biguanide?
a. Insulin glargine
b. Metformin
c. Glipizide
d. Pioglitazone
, 2
Rationale: Metformin (b) is a biguanide that decreases hepatic glucose production and
improves insulin sensitivity. Insulin glargine (a) is a long-acting insulin, glipizide (c) is a
sulfonylurea, and pioglitazone (d) is a thiazolidinedione, per ATI standards.
3. MCQ: A nurse is administering an anticoagulant to a patient with atrial fibrillation.
Which medication is a direct thrombin inhibitor?
a. Warfarin
b. Dabigatran
c. Heparin
d. Clopidogrel
Rationale: Dabigatran (b) directly inhibits thrombin, preventing clot formation. Warfarin
(a) is a vitamin K antagonist, heparin (c) enhances antithrombin, and clopidogrel (d) is an
antiplatelet, per ATI 2025 guidelines.
4. MCQ: A patient with depression is prescribed a medication. Which drug is a selective
serotonin reuptake inhibitor (SSRI)?
a. Amitriptyline
b. Sertraline
c. Bupropion
d. Phenelzine
Rationale: Sertraline (b) is an SSRI that increases serotonin levels. Amitriptyline (a) is a
tricyclic antidepressant, bupropion (c) is an NDRI, and phenelzine (d) is an MAOI, per
ATI standards.
5. MCQ: A nurse is preparing to administer a bronchodilator for asthma. Which medication
is a short-acting beta-2 agonist (SABA)?
a. Ipratropium
b. Albuterol
c. Fluticasone
d. Montelukast
Rationale: Albuterol (b) is a SABA used for acute asthma relief. Ipratropium (a) is an
anticholinergic, fluticasone (c) is a corticosteroid, and montelukast (d) is a leukotriene
modifier, per ATI guidelines.
6. MCQ: A patient with heart failure is prescribed a loop diuretic. Which medication
belongs to this class?
a. Spironolactone
b. Furosemide
c. Hydrochlorothiazide
d. Mannitol
Rationale: Furosemide (b) is a loop diuretic that promotes fluid excretion. Spironolactone
(a) is a potassium-sparing diuretic, hydrochlorothiazide (c) is a thiazide diuretic, and
mannitol (d) is an osmotic diuretic, per ATI 2025 standards.
7. MCQ: A nurse is administering an antibiotic for a bacterial infection. Which drug is a
penicillin?
a. Azithromycin
b. Amoxicillin
c. Ciprofloxacin
d. Doxycycline
Rationale: Amoxicillin (b) is a penicillin antibiotic. Azithromycin (a) is a macrolide,
, 3
ciprofloxacin (c) is a fluoroquinolone, and doxycycline (d) is a tetracycline, per ATI
guidelines.
8. MCQ: A patient with seizures is prescribed an anticonvulsant. Which medication is a
sodium channel blocker?
a. Levetiracetam
b. Carbamazepine
c. Valproate
d. Gabapentin
Rationale: Carbamazepine (b) blocks sodium channels to prevent seizures. Levetiracetam
(a), valproate (c), and gabapentin (d) have different mechanisms, per ATI 2025 standards.
9. MCQ: A nurse is preparing to administer a medication for hyperthyroidism. Which drug
is an antithyroid medication?
a. Levothyroxine
b. Methimazole
c. Liothyronine
d. Propranolol
Rationale: Methimazole (b) inhibits thyroid hormone synthesis. Levothyroxine (a) and
liothyronine (c) are thyroid replacements, and propranolol (d) is a beta-blocker, per ATI
guidelines.
10. MCQ: A patient with chronic pain is prescribed an opioid analgesic. Which medication
belongs to this class?
a. Ibuprofen
b. Morphine
c. Acetaminophen
d. Aspirin
Rationale: Morphine (b) is an opioid analgesic. Ibuprofen (a) and aspirin (d) are NSAIDs,
and acetaminophen (c) is a non-opioid analgesic, per ATI standards.
11. MCQ: A nurse is administering a medication for gout. Which drug is a xanthine oxidase
inhibitor?
a. Colchicine
b. Allopurinol
c. Probenecid
d. Indomethacin
Rationale: Allopurinol (b) reduces uric acid production. Colchicine (a) reduces
inflammation, probenecid (c) increases uric acid excretion, and indomethacin (d) is an
NSAID, per ATI 2025 guidelines.
12. MCQ: A patient with bipolar disorder is prescribed a mood stabilizer. Which drug
belongs to this class?
a. Fluoxetine
b. Lithium
c. Lorazepam
d. Risperidone
Rationale: Lithium (b) is a mood stabilizer for bipolar disorder. Fluoxetine (a) is an SSRI,
lorazepam (c) is a benzodiazepine, and risperidone (d) is an antipsychotic, per ATI
standards.
