PMHNP ANCC Review Questions and
Answers | Latest Version | 2025/2026 |
Correct & Verified
A patient taking lithium complains of increased thirst and frequent urination. What condition
should the PMHNP suspect?
A. Hypothyroidism
✔✔B. Diabetes insipidus
C. Hyponatremia
D. Neuroleptic malignant syndrome
Which neurotransmitter is primarily involved in anxiety disorders?
✔✔A. GABA
B. Dopamine
C. Glutamate
D. Acetylcholine
A 10-year-old boy has difficulty paying attention, interrupts others, and has trouble staying
seated. What is the most likely diagnosis?
1
,A. Autism Spectrum Disorder
✔✔B. ADHD
C. Conduct Disorder
D. Oppositional Defiant Disorder
Which class of medication is first-line for treating panic disorder?
A. Antipsychotics
✔✔B. SSRIs
C. Mood stabilizers
D. Stimulants
A client on clozapine presents with fever, sore throat, and malaise. What lab value is most urgent
to assess?
A. Platelets
✔✔B. Absolute neutrophil count
C. Hemoglobin
D. Blood glucose
2
,What is the mechanism of action of SSRIs?
✔✔A. Inhibit reuptake of serotonin
B. Block dopamine receptors
C. Enhance GABA activity
D. Inhibit MAO-A enzyme
In treating PTSD, which therapeutic approach focuses on gradually exposing the client to
trauma-related cues?
✔✔A. Prolonged exposure therapy
B. Supportive therapy
C. Psychoanalysis
D. Solution-focused therapy
A patient with bipolar I disorder is experiencing mania. Which medication is most appropriate?
A. Sertraline
✔✔B. Lithium
C. Diazepam
D. Donepezil
3
, A 14-year-old is defiant toward authority, frequently loses temper, and blames others for
mistakes. What is the diagnosis?
✔✔A. Oppositional Defiant Disorder
B. Conduct Disorder
C. ADHD
D. Bipolar Disorder
Which lab should be monitored regularly for a patient on valproic acid?
✔✔A. Liver function tests
B. Hemoglobin A1c
C. BUN
D. Amylase
Which of the following is most characteristic of borderline personality disorder?
✔✔A. Unstable interpersonal relationships
B. Suspiciousness and distrust
C. Grandiosity
4
Answers | Latest Version | 2025/2026 |
Correct & Verified
A patient taking lithium complains of increased thirst and frequent urination. What condition
should the PMHNP suspect?
A. Hypothyroidism
✔✔B. Diabetes insipidus
C. Hyponatremia
D. Neuroleptic malignant syndrome
Which neurotransmitter is primarily involved in anxiety disorders?
✔✔A. GABA
B. Dopamine
C. Glutamate
D. Acetylcholine
A 10-year-old boy has difficulty paying attention, interrupts others, and has trouble staying
seated. What is the most likely diagnosis?
1
,A. Autism Spectrum Disorder
✔✔B. ADHD
C. Conduct Disorder
D. Oppositional Defiant Disorder
Which class of medication is first-line for treating panic disorder?
A. Antipsychotics
✔✔B. SSRIs
C. Mood stabilizers
D. Stimulants
A client on clozapine presents with fever, sore throat, and malaise. What lab value is most urgent
to assess?
A. Platelets
✔✔B. Absolute neutrophil count
C. Hemoglobin
D. Blood glucose
2
,What is the mechanism of action of SSRIs?
✔✔A. Inhibit reuptake of serotonin
B. Block dopamine receptors
C. Enhance GABA activity
D. Inhibit MAO-A enzyme
In treating PTSD, which therapeutic approach focuses on gradually exposing the client to
trauma-related cues?
✔✔A. Prolonged exposure therapy
B. Supportive therapy
C. Psychoanalysis
D. Solution-focused therapy
A patient with bipolar I disorder is experiencing mania. Which medication is most appropriate?
A. Sertraline
✔✔B. Lithium
C. Diazepam
D. Donepezil
3
, A 14-year-old is defiant toward authority, frequently loses temper, and blames others for
mistakes. What is the diagnosis?
✔✔A. Oppositional Defiant Disorder
B. Conduct Disorder
C. ADHD
D. Bipolar Disorder
Which lab should be monitored regularly for a patient on valproic acid?
✔✔A. Liver function tests
B. Hemoglobin A1c
C. BUN
D. Amylase
Which of the following is most characteristic of borderline personality disorder?
✔✔A. Unstable interpersonal relationships
B. Suspiciousness and distrust
C. Grandiosity
4
