and Answers (2025 Update) – Chamberlain University
This document contains the complete midterm exam for NR565 Advanced Pharmacology:
Care of the Fundamentals, updated for 2025 at Chamberlain University. It includes 220
accurately verified questions and correct answers covering essential pharmacological
principles, drug classifications, clinical applications, adverse effects, and prescribing
practices. A highly valuable study resource for nurse practitioner students aiming for top
performance in their midterm assessment.
1. which schedule of drugs can APRNs prescribe: schedule II-V
2. components of prescriptive authority: the right to prescribe independently
the right to prescribe w/o limitation
3. who determines and regulates prescriptive authority: state practice and
licensure laws
4. practice authority: NPs ability to practice w/o physician oversight
5. prescriptive authority: NPs ability to prescribe meds
6. full-practice scope: NPs have the autonomy to evaluate pts, diagnose, order
and interpret tests, initiate and manage tx and prescribe meds, including
controlled substances w/o physician oversight
,7. reduced-practice scope: NPs are limited in at least one element of practice.
the state requires a formal collaborative agreement w/ an outside health
discipline for the NP to provide pt care
8. restricted-practice scope: NPs are limited in at least one element of practice
by requiring supervision, delegation, or team management by an outside
health discipline for the NP to provide pt care
9. key responsibilities of prescribing: -documentation of a provider-pt
relationship for the recipient of the prescribed meds
-documentation of a thorough hx and physical exam
-documentation of discussions regardly r/f, s/e or therapy options
-documentation of drug monitoring or titration plan
-documentation of consultations if any
-avoidance of prescribed meds for self, family or friends
10. considerations for appropriate pharmacological tx:
cost guidelines
availability
interactions
s/e
allergies
hepatic and renal function
need for monitoring
special populations
11. physiologic changes that can affect pharmacokinetics in older adults:
absorption of drugs distribution of drugs metabolism of drugs excretion of
drugs
12. how can the absorption of drugs be altered in older adults:
increased gastric pH
, decreased absorptive surface area
decreased splanchnic blood flow
decreased GI motility delayed
gastric emptying
13. how can the distribution of drugs be altered in older adults:
increased body fat
decreased lean mass
decreased total body water
decreased serum albumin
decreased CO
14. how can the metabolism of drugs be altered in older adults: decreased
hepatic blood flow decreased hepatic mass
decreased activity of hepatic enzymes
15. how can the excretion of drugs be altered in older adults: decreased renal
blood flow, GFR, tubular secretion, and # of nephrons
16. how much are older adults more likely to experience ADR: 7x
17. predisposing ADR factors in older adults: -drugs accumulation secondary
to reduced -renal function
-polypharmacy
-greater severity of illness
-presence of comorbidities
-use of drugs that have a low therapeutic index
-increased individual variation secondary to altered pharmacokinetics
-poor pt adherence
-inadequate supervision of long term therapy
18. beer's criteria: A list of medications that are generally considered
inappropriate when given to older adults