TEST BANK
iv
Introduction to Genetic Analysis
iv iv iv
Anthony J.F. Griffiths, John Doebley, Catherine Peichel, and David A. Wassarman
iv iv iv iv iv iv iv iv iv iv
12th Edition
iv
,Table of Contents
iv iv
Chapter 01 The Genetics Revolution
iv iv iv iv 1
Chapter 02 Single Gene Inheritance
iv iv iv iv 6
Chapter 03 Independent Assortment of Genes
iv iv iv iv iv 26
Chapter 04 Mapping Eukaryote Chromosomes by Recombination
iv iv iv iv iv iv 43
Chapter 05 Gene Interaction
iv iv iv 63
Chapter 06 The Genetics of Bacteria and Their Viruses
iv iv iv iv iv iv iv iv 84
Chapter 07 DNA Structure and Replication
iv iv iv iv iv 104
Chapter 08 RNA Transcription Processing and Decay
iv iv iv iv iv iv 117
Chapter 09 Proteins and Their Synthesis
iv iv iv iv iv 130
Chapter 10 Gene Isolation and Manipulation
iv iv iv iv iv 141
Chapter 11 Regulation of Gene Expression in Bacteria and Their Viruses
iv iv iv iv iv iv iv iv iv iv 160
Chapter 12 Regulation of Gene Expression in Eukaryotes
iv iv iv iv iv iv iv 175
Chapter 13 The Genetic Control of Development
iv iv iv iv iv iv 184
Chapter 14 Genomes and Genomics
iv iv iv iv 192
Chapter 15 DNA Damage Repair and Recombination
iv iv iv iv iv iv 197
Chapter 16 The Dynamic Genome Transposable Elements
iv iv iv iv iv iv 216
Chapter 17 Large Scale Chromosomal Changes
iv iv iv iv iv 225
Chapter 18 Population Genetics
iv iv iv 243
Chapter 19 The Inheritance of Complex Traits
iv iv iv iv iv iv 258
Chapter 20 Evolution of Genes and Traits
iv iv iv iv iv iv 270
, Test ivBank iv- ivIntroduction ivto ivGenetic ivAnalysis, iv12th ivEdition iv(Griffiths, iv2021)
Chapter 01: The Genetics Revolution
iv iv iv iv
1. The early 1900s was an important period for genetics due to which of the following major events?
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a. the rediscovery of Gregor Mendel's scientific findings
iv iv iv iv iv iv
b. Watson and Crick solving the structure of DNA iv iv iv iv iv iv iv
c. Walter Sutton and Theodore Boveri hypothesizing that chromosomes are the hereditary elements
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d. the rediscovery of Gregor Mendel's scientific findings and Walter Sutton and Theodore
iv iv iv iv iv iv iv iv iv iv iv
Boveri hypothesizing that chromosomes are the hereditary elements
iv iv iv iv iv iv iv iv
e. All of the answer options are correct.
iv iv iv iv iv iv
ANSWER: e i v
2. A sample of normal double-stranded DNA was found to have a guanine content of 18%. What is the
iv iv iv iv iv iv iv iv iv iv iv iv iv iv iv iv iv
expected proportion of adenine?
iv iv iv iv
a. 9%
b. 32%
c. 36%
d. 68%
e. 82%
ANSWER: b i v
3. In one strand of DNA, the nucleotide sequence is 5'-ATGC-3'. The complementary sequence in the
iv iv iv iv iv iv iv iv iv iv iv iv iv iv
other strand must be
iv iv iv iv
a. 3'-ATGC-5'.
b. 3'-TACG-5'.
c. 5'-ATCG-3'.
d. 5'-CGTA-3'.
e. 5'-TACG-3'.
ANSWER: b i v
4. How many different DNA molecules that are eight-nucleotide-pairs long are theoretically possible?
iv iv iv iv iv iv iv iv iv iv iv
a. 24
b. 32
c. 64
d. 256
e. 65,536
ANSWER: e i v
5. Which of the following is/are TRUE about genes?
iv iv iv iv iv iv iv
a. Genes are located on chromosomes. iv iv iv iv
b. Genes come in variants known as alleles. iv iv iv iv iv iv
c. Genes usually encode protein products. iv iv iv iv
d. All of the answer options are correct.
iv iv iv iv iv iv
e. None of the answer options is correct.
iv iv iv iv iv iv
ANSWER: d i v
1|Pagiv iv iv iv
e
iv
, Test ivBank iv- ivIntroduction ivto ivGenetic ivAnalysis, iv12th ivEdition iv(Griffiths, iv2021)
6. Wild cats (Felis silvestris) and common mice (Mus musculus) are diploid. In wild cats, 2n = 38, while
iv iv iv iv iv iv iv iv iv iv iv iv iv iv iv iv iv
in common mice, 2n = 40. Based on this information, we can conclude that wild-cat cells have
iv iv iv iv iv iv iv iv iv iv iv iv iv iv iv iv iv
a. less DNA than common-mouse cells.
iv iv iv iv
b. smaller genomes than common-mouse cells. iv iv iv iv
c. fewer DNA molecules than common-mouse cells.
iv iv iv iv iv
d. fewer genes than common-mouse cells.
iv iv iv iv
e. fewer sets of chromosomes than common-mouse cells.
iv iv iv iv iv iv
ANSWER: c i v
7. Which of the following is a component of DNA?
iv iv iv iv iv iv iv iv
a. alanine
b. arginine
c. cysteine
d. guanine
e. tyrosine
ANSWER: d i v
8. Which of the following is/are TRUE of the DNA structure solved by Watson and Crick?
iv iv iv iv iv iv iv iv iv iv iv iv iv iv
a. It is a double-helical structure.
iv iv iv iv
b. Sugar–phosphate backbone is always toward the outside of the DNA. iv iv iv iv iv iv iv iv iv
c. There are two hydrogen bonds between A and T and three hydrogen bonds between C and G.
iv iv iv iv iv iv iv iv iv iv iv iv iv iv iv iv
d. There are four types of nitrogenous bases.
iv iv iv iv iv iv
e. All of the answer options are correct.
iv iv iv iv iv iv
ANSWER: e i v
9. Which of the following is a CORRECT representation of the central dogma?
iv iv iv iv iv iv iv iv iv iv iv
a. RNA → DNA → protein iv iv iv iv
b. protein → DNA → RNA iv iv iv iv
c. DNA → RNA → protein iv iv iv iv
d. DNA → protein → DNA iv iv iv iv
e. None of the answer options is correct.
iv iv iv iv iv iv
ANSWER: c i v
10. You have come across a dog (named Cindy) that does not have a tail. Interestingly, all the puppies
iv iv iv iv iv iv iv iv iv iv iv iv iv iv iv iv iv
produced by this dog don't have a tail. If the lack of tail is caused by a genetic mutation, where has this
iv iv iv iv iv iv iv iv iv iv iv iv iv iv iv iv iv iv iv iv iv iv
mutation most likely taken place?
iv iv iv iv iv
a. in Cindy's gametes
iv iv
b. in the cells that should normally have given rise to Cindy's tail
iv iv iv iv iv iv iv iv iv iv iv
c. in the cells that should normally have given rise to Cindy's and her puppies' tails
iv iv iv iv iv iv iv iv iv iv iv iv iv iv
d. in all of Cindy's cells (including her gametes)
iv iv iv iv iv iv iv
e. in a gamete of one of Cindy's parents
iv iv iv iv iv iv iv
ANSWER: a i v
11. Which of the following features makes a species suitable as a model organism?
iv iv iv iv iv iv iv iv iv iv iv iv
2|Pagiv iv iv iv
e
iv
iv
Introduction to Genetic Analysis
iv iv iv
Anthony J.F. Griffiths, John Doebley, Catherine Peichel, and David A. Wassarman
iv iv iv iv iv iv iv iv iv iv
12th Edition
iv
,Table of Contents
iv iv
Chapter 01 The Genetics Revolution
iv iv iv iv 1
Chapter 02 Single Gene Inheritance
iv iv iv iv 6
Chapter 03 Independent Assortment of Genes
iv iv iv iv iv 26
Chapter 04 Mapping Eukaryote Chromosomes by Recombination
iv iv iv iv iv iv 43
Chapter 05 Gene Interaction
iv iv iv 63
Chapter 06 The Genetics of Bacteria and Their Viruses
iv iv iv iv iv iv iv iv 84
Chapter 07 DNA Structure and Replication
iv iv iv iv iv 104
Chapter 08 RNA Transcription Processing and Decay
iv iv iv iv iv iv 117
Chapter 09 Proteins and Their Synthesis
iv iv iv iv iv 130
Chapter 10 Gene Isolation and Manipulation
iv iv iv iv iv 141
Chapter 11 Regulation of Gene Expression in Bacteria and Their Viruses
iv iv iv iv iv iv iv iv iv iv 160
Chapter 12 Regulation of Gene Expression in Eukaryotes
iv iv iv iv iv iv iv 175
Chapter 13 The Genetic Control of Development
iv iv iv iv iv iv 184
Chapter 14 Genomes and Genomics
iv iv iv iv 192
Chapter 15 DNA Damage Repair and Recombination
iv iv iv iv iv iv 197
Chapter 16 The Dynamic Genome Transposable Elements
iv iv iv iv iv iv 216
Chapter 17 Large Scale Chromosomal Changes
iv iv iv iv iv 225
Chapter 18 Population Genetics
iv iv iv 243
Chapter 19 The Inheritance of Complex Traits
iv iv iv iv iv iv 258
Chapter 20 Evolution of Genes and Traits
iv iv iv iv iv iv 270
, Test ivBank iv- ivIntroduction ivto ivGenetic ivAnalysis, iv12th ivEdition iv(Griffiths, iv2021)
Chapter 01: The Genetics Revolution
iv iv iv iv
1. The early 1900s was an important period for genetics due to which of the following major events?
iv iv iv iv iv iv iv iv iv iv iv iv iv iv iv iv
a. the rediscovery of Gregor Mendel's scientific findings
iv iv iv iv iv iv
b. Watson and Crick solving the structure of DNA iv iv iv iv iv iv iv
c. Walter Sutton and Theodore Boveri hypothesizing that chromosomes are the hereditary elements
iv iv iv iv iv iv iv iv iv iv iv
d. the rediscovery of Gregor Mendel's scientific findings and Walter Sutton and Theodore
iv iv iv iv iv iv iv iv iv iv iv
Boveri hypothesizing that chromosomes are the hereditary elements
iv iv iv iv iv iv iv iv
e. All of the answer options are correct.
iv iv iv iv iv iv
ANSWER: e i v
2. A sample of normal double-stranded DNA was found to have a guanine content of 18%. What is the
iv iv iv iv iv iv iv iv iv iv iv iv iv iv iv iv iv
expected proportion of adenine?
iv iv iv iv
a. 9%
b. 32%
c. 36%
d. 68%
e. 82%
ANSWER: b i v
3. In one strand of DNA, the nucleotide sequence is 5'-ATGC-3'. The complementary sequence in the
iv iv iv iv iv iv iv iv iv iv iv iv iv iv
other strand must be
iv iv iv iv
a. 3'-ATGC-5'.
b. 3'-TACG-5'.
c. 5'-ATCG-3'.
d. 5'-CGTA-3'.
e. 5'-TACG-3'.
ANSWER: b i v
4. How many different DNA molecules that are eight-nucleotide-pairs long are theoretically possible?
iv iv iv iv iv iv iv iv iv iv iv
a. 24
b. 32
c. 64
d. 256
e. 65,536
ANSWER: e i v
5. Which of the following is/are TRUE about genes?
iv iv iv iv iv iv iv
a. Genes are located on chromosomes. iv iv iv iv
b. Genes come in variants known as alleles. iv iv iv iv iv iv
c. Genes usually encode protein products. iv iv iv iv
d. All of the answer options are correct.
iv iv iv iv iv iv
e. None of the answer options is correct.
iv iv iv iv iv iv
ANSWER: d i v
1|Pagiv iv iv iv
e
iv
, Test ivBank iv- ivIntroduction ivto ivGenetic ivAnalysis, iv12th ivEdition iv(Griffiths, iv2021)
6. Wild cats (Felis silvestris) and common mice (Mus musculus) are diploid. In wild cats, 2n = 38, while
iv iv iv iv iv iv iv iv iv iv iv iv iv iv iv iv iv
in common mice, 2n = 40. Based on this information, we can conclude that wild-cat cells have
iv iv iv iv iv iv iv iv iv iv iv iv iv iv iv iv iv
a. less DNA than common-mouse cells.
iv iv iv iv
b. smaller genomes than common-mouse cells. iv iv iv iv
c. fewer DNA molecules than common-mouse cells.
iv iv iv iv iv
d. fewer genes than common-mouse cells.
iv iv iv iv
e. fewer sets of chromosomes than common-mouse cells.
iv iv iv iv iv iv
ANSWER: c i v
7. Which of the following is a component of DNA?
iv iv iv iv iv iv iv iv
a. alanine
b. arginine
c. cysteine
d. guanine
e. tyrosine
ANSWER: d i v
8. Which of the following is/are TRUE of the DNA structure solved by Watson and Crick?
iv iv iv iv iv iv iv iv iv iv iv iv iv iv
a. It is a double-helical structure.
iv iv iv iv
b. Sugar–phosphate backbone is always toward the outside of the DNA. iv iv iv iv iv iv iv iv iv
c. There are two hydrogen bonds between A and T and three hydrogen bonds between C and G.
iv iv iv iv iv iv iv iv iv iv iv iv iv iv iv iv
d. There are four types of nitrogenous bases.
iv iv iv iv iv iv
e. All of the answer options are correct.
iv iv iv iv iv iv
ANSWER: e i v
9. Which of the following is a CORRECT representation of the central dogma?
iv iv iv iv iv iv iv iv iv iv iv
a. RNA → DNA → protein iv iv iv iv
b. protein → DNA → RNA iv iv iv iv
c. DNA → RNA → protein iv iv iv iv
d. DNA → protein → DNA iv iv iv iv
e. None of the answer options is correct.
iv iv iv iv iv iv
ANSWER: c i v
10. You have come across a dog (named Cindy) that does not have a tail. Interestingly, all the puppies
iv iv iv iv iv iv iv iv iv iv iv iv iv iv iv iv iv
produced by this dog don't have a tail. If the lack of tail is caused by a genetic mutation, where has this
iv iv iv iv iv iv iv iv iv iv iv iv iv iv iv iv iv iv iv iv iv iv
mutation most likely taken place?
iv iv iv iv iv
a. in Cindy's gametes
iv iv
b. in the cells that should normally have given rise to Cindy's tail
iv iv iv iv iv iv iv iv iv iv iv
c. in the cells that should normally have given rise to Cindy's and her puppies' tails
iv iv iv iv iv iv iv iv iv iv iv iv iv iv
d. in all of Cindy's cells (including her gametes)
iv iv iv iv iv iv iv
e. in a gamete of one of Cindy's parents
iv iv iv iv iv iv iv
ANSWER: a i v
11. Which of the following features makes a species suitable as a model organism?
iv iv iv iv iv iv iv iv iv iv iv iv
2|Pagiv iv iv iv
e
iv