STUDENT C O M P A N I O N
F U N D A M
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E N T A L S O F
Biochemistry
LIFEAT r
THE MOLECULAR
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LEVEL r
Voet Voet Pratt
F O U R T H E D I T I O N
Akif Uzman Jerry Johnson Joseph Eichberg William Widger
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Donald Voet Judith G. Voet CharlotteW.Pratt
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FUNDAMENTALS OF r
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LIFE AT THE MOLECULAR LEVEL
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Fourth Edition r
Akif Uzman
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University of Houston r r
Jerry Johnson
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University of Houston r r
Joseph Eichberg r
University of Houston r r
William Widger r
University of Houston r r
Donald Voet r
University of Pennsylvania r r
Judith G. Voet r r
Swarthmore College r
Charlotte W. Pratt r r
Seattle, Washington r
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Molecular structures clockwise from top: based on X-ray structures that were respectively determined by
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Richard Dickerson and Horace Drew, Caltech; Gerard Bunick, University of Tennessee; Thomas Steitz,
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Yale University; Alfonso Mondragón, Northwestern University; Venki Ramakrishnan, MRC Laboratory of
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Molecular Biology, Cambridge, U.K.; Andrew Leslie and John Walker, MRC Laboratoryof Molecular
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Biology, Cambridge, U.K.
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Student Companion (paperback) r r ISBN-13 978-1-1182-1827-3 r
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F U N D A M
r
E N T A L S O F
Biochemistry
LIFEAT r
THE MOLECULAR
r
LEVEL r
Voet Voet Pratt
F O U R T H E D I T I O N
Akif Uzman Jerry Johnson Joseph Eichberg William Widger
r r r r
Donald Voet Judith G. Voet CharlotteW.Pratt
r r r r r r
,This page is intentionally left blank
r r r r r
,STUDENT COMPANION TO ACCOMPANY r r r
FUNDAMENTALS OF r
BIOCHEMISTRY
LIFE AT THE MOLECULAR LEVEL
r r r r
Fourth Edition r
Akif Uzman
r
University of Houston r r
Jerry Johnson
r
University of Houston r r
Joseph Eichberg r
University of Houston r r
William Widger r
University of Houston r r
Donald Voet r
University of Pennsylvania r r
Judith G. Voet r r
Swarthmore College r
Charlotte W. Pratt r r
Seattle, Washington r
JOHN WILEY & SONS, INC
r r r r
, Cover Designer Madelyn Lesure
r r r
Cover Illustration Norm Christiansen
r r r r
Cover Photos
r r
(Vitruvian Man): © Odysseus/Alamy and © Dennis Hallinan/Alamy r r r r r r r
Molecular structures clockwise from top: based on X-ray structures that were respectively determined by
r r r r r r r r r r r r r
Richard Dickerson and Horace Drew, Caltech; Gerard Bunick, University of Tennessee; Thomas Steitz,
r r r r r r r r r r r r r
Yale University; Alfonso Mondragón, Northwestern University; Venki Ramakrishnan, MRC Laboratory of
r r r r r r r r r r r
Molecular Biology, Cambridge, U.K.; Andrew Leslie and John Walker, MRC Laboratoryof Molecular
r r r r r r r r r r r r r
Biology, Cambridge, U.K.
r r r
Founded in 1807, John Wiley & Sons, Inc. has been a valued source of knowledge and understanding for more
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than 200 years, helping people around the world meet their needs and fulfill their aspirations. Our company is
r r r r r r r r r r r r r r r r r r
built on a foundation of principles that include responsibility to the communities we serve andwhere we live
r r r r r r r r r r r r r r r r r r
and work. In 2008, we launched a Corporate Citizenship Initiative, a global effort to address the environmental,
r r r r r r r r r r r r r r r r r
social, economic, and ethical challenges we face in our business. Among the issues we are addressing are
r r r r r r r r r r r r r r r r r
carbon impact, paper specifications and procurement, ethical conduct within our business and among our
r r r r r r r r r r r r r r
vendors, and community and charitable support. For more information, please visit our website:
r r r r r r r r r r r r r
www.wiley.com/go/citizenship.
r
Copyright © 2012 r r John Wiley & Sons, Inc. r r r r
All rights reserved. No part of this publication may be reproduced, stored in a retrieval system or transmitted in
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any form or by any means, electronic, mechanical, photocopying, recording, scanning or otherwise, except as
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permitted under Sections 107 or 108 of the 1976 United States Copyright Act, without either the prior written
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permission of the Publisher, or authorization through payment of the appropriate per-copy fee to the
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Copyright Clearance Center, Inc., 222 Rosewood Drive, Danvers, MA 01923, website www.copyright.com.
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Requests to the Publisher for permission should be addressed to thePermissions Department, John Wiley &
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Sons, Inc. 111 River Street, Hoboken, NJ 07030-5774, (201) 748-6011, fax (201) 748-6008, website
r r r r r r r r r r r r r r
http://www.wiley.com/go/permissions.
r
To order books or for customer service, please call 1-800-CALL WILEY (225-5945).
r r r r r r r r r r r
Student Companion (paperback) r r ISBN-13 978-1-1182-1827-3 r
Printed in the United States of America
r r r r r r
10 9 8 7 6 5 4 3 2 1
r r r r r r r r r r