Warfarin interactions
Ans: FLAMES
o Fluconazole
o Levofloxacin (really increase INR)
o Amiodarone (worse interaction - decrease warfarin dose *by 50%*)
o Metronidazole (decrease warfarin dose *by 1/3*)
o Erythromycin (macrolides in general but this one is the worse)
o Sulf-TMP
CYP Inducers
Ans: PS PORCS
o Phenytoin
o Smoking
o Phenobarbital
o Oxcarbazepine (and eslicarbamazepine)
o Rifampin
o Carbamazepine (and its auto-inducer)
o St. John's wort
CYP Inhibitors
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,Ans: G PACMAN
o Grapefruit
o Protease Inhibitors
o Azoles
o C - cyclosporine, cimetidine, cobicistat
o Macrolides
o Amiodarone
o Non-DHP CCBs (diltiazem and verapamil)
5 G's (natural products) that increase bleeding risk
Ans: o Gingko
o Garlic
o Ginger
o Glucosamine
o Gingseng
Drugs that require non-PVC containers
Ans: LATTINS
o Lorazepam
o Amiodarone
o Tacrolimus
o Taxanes
o Insulin
o Nitroglycerin
o Sufentanil
Common Drugs that require SALINE only
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, Ans: ACID APE
♣ Ampicillin
♣ Caspofungin
♣ Infliximab
♣ Daptomycin
♣ Ampicillin/ sulbactam
♣ Phenytoin
♣ Ertapenem
Common Drugs that require dextrose only
Ans: BOAS
♣ Bactrim (Sulf -TMP)
♣ Oxaliplatin
♣ Ampotericin B
♣ Synercid (quinupristin/dalfopristin)
Drugs that require a filter
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