CITI Certification Questions and Correct Answers/ Latest Update / Already Graded

Which of the following is an example of how the principle of beneficence can be applied to a study employing human subjects? Ans: Determining that the study has a maximization of benefits and a minimization of risks. Which of the following are the three principles discussed in the Belmont Report? Ans: Respect for Persons, Beneficence, Justice The Belmont Report's principle of respect for persons incorporates at least two ethical convictions: first, that individuals should be treated as autonomous agents, and second, that: Ans: Persons with diminished autonomy are entitled to protection. According to the authors, there are four common abuses that historically are described as giving rise to vulnerability. Which response below contains the correct four? Ans: Physical control, coercion, undue influence, and manipulation All rights reserved © 2025/ 2026 | Page | 2 subjects? When an IRB is reviewing a research study and they are considering if a potential subject population is vulnerable, they should consider: Ans: Is there a power differential between researchers and Subjects with a serious illness may be at risk for exploitation because they may be desperate for a possible cure. This is an example of: Ans: Medical vulnerability The NBAC looks at characteristics individuals might have that would prevent them from being able to provide voluntary informed consent. The traits may be thought of as falling into six broad areas: cognitive or communicative, institutional, deferential, medical, economic, and social. Prospective research subjects who are not able to comprehend information, deliberate, and make decisions about participation in a proposed research study have a: Ans: Cognitive or communicative vulnerability Which is an example of a situation where deferential vulnerability might be a factor? Ans: A physician recruiting patients to be subjects All rights reserved © 2025/ 2026 | Page | 3 An example of an individual financial COI is: researcher's study. Ans: A researcher's spouse holds equity in a publicly traded pharmaceutical company that is also the sponsor of the A researcher's membership on an advisory board with an organization sponsoring research can create a COI because: Ans: It may be difficult for the researcher to appear neutral, as the researcher may have an interest in the research's success The COI management plan aims to: Ans: Provide procedures or extras steps to be taken to minimize the risk of bias when a COI is disclosed research The peer review process can create conflicts of interest because the choice of who reviews a potentially publishable project may show: Ans: There may be bias by the peer reviewer as to the area of A researcher calls you stating that he plans to submit a proposal to the NIH for a human subjects research study. He wants to know at what All rights reserved © 2025/ 2026 | Page | 4 point he and his study team must submit COI disclosures to comply with the PHS regulation. Ans: No later than the time of proposal submission