ADVANCED PATHOPHYSIOLOGY
EXAM 1 NEWEST 2025 ACTUAL
EXAM
314 QUESTIONS AND CORRECT
DETAILED ANSWERS WITH
RATIONALES VERIFIED ANSWERS
GRADED A+
,Lab Tests
Q: Which of the following pharmacokinetic
changes is most likely to occur with normal
aging?
A. Increased first pass metabolism
B. Increased gastric pH
C. Increased hepatic blood flow
D. Increased total body water
B. Increased gastric pH
,Q: Which of the following describes both the
correct pharmacokinetic change that occurs
with normal aging and the correct effect on
drug therapy?
A. Decreased GFR = increased excretion of
renally cleared
drugs
B. Decreased liver perfusion = increased
clearance for drugs through first pass
metabolism
C. Increased gastric pH = decreased
absorption of drugs requiring an acidic
environment
, D. Increased total body fat = decreased half-
life of lipid soluble drugs
C. Increased gastric pH = decreased absorption
of drugs requiring an acidic environment
Q: Which neurotransmitter excites receptors on
the bladder smooth muscle leading to bladder
contractions?
A. Acetylcholine
B. Dopamine
C. Histamine
D. Serotonin
EXAM 1 NEWEST 2025 ACTUAL
EXAM
314 QUESTIONS AND CORRECT
DETAILED ANSWERS WITH
RATIONALES VERIFIED ANSWERS
GRADED A+
,Lab Tests
Q: Which of the following pharmacokinetic
changes is most likely to occur with normal
aging?
A. Increased first pass metabolism
B. Increased gastric pH
C. Increased hepatic blood flow
D. Increased total body water
B. Increased gastric pH
,Q: Which of the following describes both the
correct pharmacokinetic change that occurs
with normal aging and the correct effect on
drug therapy?
A. Decreased GFR = increased excretion of
renally cleared
drugs
B. Decreased liver perfusion = increased
clearance for drugs through first pass
metabolism
C. Increased gastric pH = decreased
absorption of drugs requiring an acidic
environment
, D. Increased total body fat = decreased half-
life of lipid soluble drugs
C. Increased gastric pH = decreased absorption
of drugs requiring an acidic environment
Q: Which neurotransmitter excites receptors on
the bladder smooth muscle leading to bladder
contractions?
A. Acetylcholine
B. Dopamine
C. Histamine
D. Serotonin