Neurotransmitter Table
To be completed throughout course and submitted in Week
8*
Neurotransmitter Table
Neuro Receptor Location/Function/ Distribution Drug classes that Specific medications that target this
transmitter Subtype Effects/symptoms of (ie: CNS/PNS, target this neurotransmitter or receptor
excess or deficit if GI, vascular) neurotransmitter or
applicable receptor
Glutamate AMPA Ligand-gated ion channels CNS NMDA glutamate Memantine, PCP, Ketamine
Modulates cell excitability antagonist Dextromethorphan, Dextromethadone,
by allowing the flow of Barbiturates Parampanel
calcium and sodium ions Antiepileptics
into the cell. Located at
the CNS in neurons and
glia.
Excess has resulted in
schizophrenia, epilepsy,
and mania.
NMDA Ligand-gated ion CNS NMDA receptor Memantine, Amantadine, Ketamine,
channels, strengthens antagonist Dextromethorphan, Methadone,
synapses and is involved Antipsychotics Loop Dextropropoxyphene,
in strong memory Diuretics Opiates Ketobemidone, Furosemide, Haldol,
formation. Excess is Antidepressants Tramadol
associated with memory
and learning impairments,
psychosis, and excitotoxic
brain injury.
GABA GABA a Ligand-gated ion channels CNS Limbic, Benzodiazepines, Lorazepam, Clonazepam, Alprazolam
Functions as postsynaptic system, Striatum Hypnotics, Zolpidem, Zopiclone, zaleplon
inhibition by CI-influx Medulla, Spinal Neuroactive Allopregnanolone
Inotropic receptor Reduces Cord, pancreas steroids
fear, anxiety& convulsions
GABA b G-Protein Linked CNS/PNS GABA-b receptor Baclofen, Arbaclofen, Placarbil,
Functions as pre- agonists, Antispastic Propofol
synaptic inhibition by Anesthetics
lowering calcium ion
entry while post-synaptic
inhibitions
Chamberlain University | National Management Offices | 500 W. Monroe St., Suite 28 | Chicago, IL 60661
by increasing potassium ©2021 Chamberlain University LLC. All rights reserved.
, Neurotransmitter Table
To be completed throughout course and submitted in Week
8*
To be completed throughout course and submitted in Week
8*
Neurotransmitter Table
Neuro Receptor Location/Function/ Distribution Drug classes that Specific medications that target this
transmitter Subtype Effects/symptoms of (ie: CNS/PNS, target this neurotransmitter or receptor
excess or deficit if GI, vascular) neurotransmitter or
applicable receptor
Glutamate AMPA Ligand-gated ion channels CNS NMDA glutamate Memantine, PCP, Ketamine
Modulates cell excitability antagonist Dextromethorphan, Dextromethadone,
by allowing the flow of Barbiturates Parampanel
calcium and sodium ions Antiepileptics
into the cell. Located at
the CNS in neurons and
glia.
Excess has resulted in
schizophrenia, epilepsy,
and mania.
NMDA Ligand-gated ion CNS NMDA receptor Memantine, Amantadine, Ketamine,
channels, strengthens antagonist Dextromethorphan, Methadone,
synapses and is involved Antipsychotics Loop Dextropropoxyphene,
in strong memory Diuretics Opiates Ketobemidone, Furosemide, Haldol,
formation. Excess is Antidepressants Tramadol
associated with memory
and learning impairments,
psychosis, and excitotoxic
brain injury.
GABA GABA a Ligand-gated ion channels CNS Limbic, Benzodiazepines, Lorazepam, Clonazepam, Alprazolam
Functions as postsynaptic system, Striatum Hypnotics, Zolpidem, Zopiclone, zaleplon
inhibition by CI-influx Medulla, Spinal Neuroactive Allopregnanolone
Inotropic receptor Reduces Cord, pancreas steroids
fear, anxiety& convulsions
GABA b G-Protein Linked CNS/PNS GABA-b receptor Baclofen, Arbaclofen, Placarbil,
Functions as pre- agonists, Antispastic Propofol
synaptic inhibition by Anesthetics
lowering calcium ion
entry while post-synaptic
inhibitions
Chamberlain University | National Management Offices | 500 W. Monroe St., Suite 28 | Chicago, IL 60661
by increasing potassium ©2021 Chamberlain University LLC. All rights reserved.
, Neurotransmitter Table
To be completed throughout course and submitted in Week
8*
